检索结果 - Tesauro, Cinzia

Swapping of The N-Terminal Domain of Human Topoisomerase 1B with the Corresponding Plasmodium Falciparum Counterpart Strongly Impairs Enzyme Activity 由 Dasari, Jagadish Babu, Soren, Bini Chhetri, Ottaviani, Alessio, Tesauro, Cinzia, Marino, Simona, Messina, Beatrice, Fiorani, Paola

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Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin 由 D'Annessa, Ilda, Tesauro, Cinzia, Fiorani, Paola, Chillemi, Giovanni, Castelli, Silvia, Vassallo, Oscar, Capranico, Giovanni, Desideri, Alessandro

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Replacement of the Human Topoisomerase Linker Domain with the Plasmodial Counterpart Renders the Enzyme Camptothecin Resistant 由 Arnò, Barbara, D’Annessa, Ilda, Tesauro, Cinzia, Zuccaro, Laura, Ottaviani, Alessio, Knudsen, Birgitta, Fiorani, Paola, Desideri, Alessandro

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Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant 由 Fiorani, Paola, Tesauro, Cinzia, Mancini, Giordano, Chillemi, Giovanni, D'A;nnessa, Ilda, Graziani, Grazia, Tentori, Lucio, Muzi, Alessia, Desideri, Alessandro

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A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism 由 Arnò, Barbara, Coletta, Andrea, Tesauro, Cinzia, Zuccaro, Laura, Fiorani, Paola, Lentini, Sara, Galloni, Pierluca, Conte, Valeria, Floris, Barbara, Desideri, Alessandro

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Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico 由 Tesauro, Cinzia, Morozzo della Rocca, Blasco, Ottaviani, Alessio, Coletta, Andrea, Zuccaro, Laura, Arnò, Barbara, D'Annessa, Ilda, Fiorani, Paola, Desideri, Alessandro

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Decreased Camptothecin Sensitivity of the Stem-Cell-Like Fraction of Caco2 Cells Correlates with an Altered Phosphorylation Pattern of Topoisomerase I 由 Roy, Amit, Tesauro, Cinzia, Frøhlich, Rikke, Hede, Marianne S., Nielsen, Maria J., Kjeldsen, Eigil, Bonven, Bjarne, Stougaard, Magnus, Gromova, Irina, Knudsen, Birgitta R.

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Different Camptothecin Sensitivities in Subpopulations of Colon Cancer Cells Correlate with Expression of Different Phospho-Isoforms of Topoisomerase I with Different Activities 由 Tesauro, Cinzia, Keller, Josephine Geertsen, Gromova, Irina, Gromov, Pavel, Frøhlich, Rikke, Erlandsen, Jens Uldum, Andersen, Anni H., Stougaard, Magnus, Knudsen, Birgitta R.

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Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers 由 Tesauro, Cinzia, Graziani, Grazia, Arnò, Barbara, Zuccaro, Laura, Muzi, Alessia, D’Annessa, Ilda, Santori, Elettra, Tentori, Lucio, Leonetti, Carlo, Fiorani, Paola, Desideri, Alessandro

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Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1 由 Petersen, Kamilla Vandsø, Selas, Asier, Hymøller, Kirstine Mejlstrup, Mizielinski, Karol, Thorsager, Maria, Stougaard, Magnus, Alonso, Concepcion, Palacios, Francisco, Pérez-Pertejo, Yolanda, Reguera, Rosa M., Balaña-Fouce, Rafael, Knudsen, Birgitta R., Tesauro, Cinzia

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Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX 由 Schröder, Sarah K., Schüler, Herdit M., Petersen, Kamilla V., Tesauro, Cinzia, Knudsen, Birgitta R., Pedersen, Finn S., Krus, Frederike, Buhl, Eva M., Roeb, Elke, Roderfeld, Martin, Borojevic, Radovan, Almeida, Jamie L., Weiskirchen, Ralf

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Topoisomerase I activity and sensitivity to camptothecin in breast cancer-derived cells: a comparative study 由 Tesauro, Cinzia, Simonsen, Anne Katrine, Andersen, Marie Bech, Petersen, Kamilla Wandsoe, Kristoffersen, Emil Laust, Algreen, Line, Hansen, Noriko Yokoyama, Andersen, Anne Bech, Jakobsen, Ann Katrine, Stougaard, Magnus, Gromov, Pavel, Knudsen, Birgitta R., Gromova, Irina

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Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation 由 Keller, Josephine Geertsen, Hymøller, Kirstine Mejlstrup, Thorsager, Maria Eriksen, Hansen, Noriko Y, Erlandsen, Jens Uldum, Tesauro, Cinzia, Simonsen, Anne Katrine W, Andersen, Anne Bech, Vandsø Petersen, Kamilla, Holm, Lise Lolle, Stougaard, Magnus, Andresen, Brage Storstein, Kristensen, Peter, Frøhlich, Rikke, Knudsen, Birgitta R

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A Droplet Microfluidics Platform for Highly Sensitive and Quantitative Detection of Malaria Causing Plasmodium Parasites Based on Enzyme Activity Measurement 由 Juul, Sissel, Nielsen, Christine J. F., Labouriau, Rodrigo, Roy, Amit, Tesauro, Cinzia, Jensen, Pia W., Harmsen, Charlotte, Kristoffersen, Emil L., Chiu, Ya-Ling, Frøhlich, Rikke, Fiorani, Paola, Cox-Singh, Janet, Tordrup, David, Koch, Jørn, Bienvenu, Anne-Lise, Desideri, Alessandro, Picot, Stephane, Petersen, Eskild, Leong, Kam W., Ho, Yi-Ping, Stougaard, Magnus, Knudsen, Birgitta R.

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