Resultats de la cerca - Tarek Z. Deeb

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  1. 1
    Possible alterations in GABA<sub>A</sub> receptor signaling that underlie benzodiazepine‐resistant seizures

    Possible alterations in GABA<sub>A</sub> receptor signaling that underlie benzodiazepine‐resistant seizures per Tarek Z. Deeb, Jamie Maguire, Stephen J. Moss

    Publicat 2012
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  2. 2
    Regulation of GABAARs by Phosphorylation

    Regulation of GABAARs by Phosphorylation per Yasuko Nakamura, Laura M. Darnieder, Tarek Z. Deeb, Stephen J. Moss

    Publicat 2014
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  3. 3
    NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor–mediated currents

    NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor–mediated currents per Henry H.C. Lee, Tarek Z. Deeb, Joshua Walker, Paul Davies, Stephen J. Moss

    Publicat 2011
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  4. 4
    Potentiating KCC2 activity is sufficient to limit the onset and severity of seizures

    Potentiating KCC2 activity is sufficient to limit the onset and severity of seizures per Yvonne E. Moore, Tarek Z. Deeb, Heramb Chadchankar, Nicholas J. Brandon, Stephen J. Moss

    Publicat 2018
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  5. 5
    Modulation of neuronal activity by phosphorylation of the K–Cl cotransporter KCC2

    Modulation of neuronal activity by phosphorylation of the K–Cl cotransporter KCC2 per Kristopher T. Kahle, Tarek Z. Deeb, Martin Puskarjov, Liliya Silayeva, Bo Liang, Kai Kaila, Stephen J. Moss

    Publicat 2013
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  6. 6
    Compromising KCC2 transporter activity enhances the development of continuous seizure activity

    Compromising KCC2 transporter activity enhances the development of continuous seizure activity per Matt R. Kelley, Tarek Z. Deeb, Nicholas J. Brandon, John Dunlop, Paul Davies, Stephen J. Moss

    Publicat 2016
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  7. 7
    Developmental Regulation of KCC2 Phosphorylation Has Long-Term Impacts on Cognitive Function

    Developmental Regulation of KCC2 Phosphorylation Has Long-Term Impacts on Cognitive Function per Yvonne E. Moore, Leslie Conway, Heike J. Wobst, Nicholas J. Brandon, Tarek Z. Deeb, Stephen J. Moss

    Publicat 2019
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  8. 8
    Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged γ-Aminobutyric Acid Receptor, Type A (GABAA), α2 Subunit Knock-in Mouse

    Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged γ-Aminobutyric Acid Receptor, Type A (GABAA), α2 Subunit Knock-in Mouse per Yasuko Nakamura, Danielle Morrow, Amit Modgil, Déborah Huyghe, Tarek Z. Deeb, Michael J. Lumb, Paul Davies, Stephen J. Moss

    Publicat 2016
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  9. 9
    Common Determinants of Single Channel Conductance within the Large Cytoplasmic Loop of 5-Hydroxytryptamine Type 3 and α4β2 Nicotinic Acetylcholine Receptors

    Common Determinants of Single Channel Conductance within the Large Cytoplasmic Loop of 5-Hydroxytryptamine Type 3 and α4β2 Nicotinic Acetylcholine Receptors per Tim G. Hales, James I. Dunlop, Tarek Z. Deeb, Jane E. Carland, Stephen P. Kelley, Jeremy J. Lambert, John A. Peters

    Publicat 2006
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  10. 10
    Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy

    Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy per Matt R. Kelley, Ross A. Cardarelli, Joshua L. Smalley, Thomas A. Ollerhead, Peter M. Andrew, Nicholas J. Brandon, Tarek Z. Deeb, Stephen J. Moss

    Publicat 2018
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  11. 11
    Postsynaptic GABA<sub>B</sub>Receptor Activity Regulates Excitatory Neuronal Architecture and Spatial Memory

    Postsynaptic GABA<sub>B</sub>Receptor Activity Regulates Excitatory Neuronal Architecture and Spatial Memory per Miho Terunuma, Raquel Revilla-Sanchez, Isabel M. Quadros, Qiudong Deng, Tarek Z. Deeb, M. Lumb, Piotr Siciński, Philip G. Haydon, Menelas N. Pangalos, Stephen J. Moss

    Publicat 2014
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  12. 12
    Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABA<sub>A</sub>receptors at inhibitory synapses

    Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABA<sub>A</sub>receptors at inhibitory synapses per Jayanta Mukherjee, Ross A. Cardarelli, Yasmine Cantaut-Belarif, Tarek Z. Deeb, Deepak P. Srivastava, Shiva K. Tyagarajan, Menelas N. Pangalos, Antoine Triller, Jamie Maguire, Nicholas J. Brandon, Stephen J. Moss

    Publicat 2017
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  13. 13
    KCC2 activity is critical in limiting the onset and severity of status epilepticus

    KCC2 activity is critical in limiting the onset and severity of status epilepticus per Liliya Silayeva, Tarek Z. Deeb, Rochelle M. Hines, Matt R. Kelley, Michaelanne B. Munoz, Henry H.C. Lee, Nicholas J. Brandon, John Dunlop, Jaime L. Maguire, Paul Davies, Stephen J. Moss

    Publicat 2015
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  14. 14
    Deficits in the activity of presynaptic γ-aminobutyric acid type B receptors contribute to altered neuronal excitability in fragile X syndrome

    Deficits in the activity of presynaptic γ-aminobutyric acid type B receptors contribute to altered neuronal excitability in fragile X syndrome per Ji-Yong Kang, Jayashree Chadchankar, Thuy N. Vien, Michelle I. Mighdoll, Thomas M. Hyde, Robert J. Mather, Tarek Z. Deeb, Menelas N. Pangalos, Nicholas J. Brandon, John Dunlop, Stephen J. Moss

    Publicat 2017
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  15. 15
    Developmental seizures and mortality result from reducing GABAA receptor α2-subunit interaction with collybistin

    Developmental seizures and mortality result from reducing GABAA receptor α2-subunit interaction with collybistin per Rochelle M. Hines, Hans Michael Maric, Dustin J. Hines, Amit Modgil, Patrizia Panzanelli, Yasuko Nakamura, Anna Nathanson, A.J. Cross, Tarek Z. Deeb, Nicholas J. Brandon, Paul Davies, Jean‐Marc Fritschy, Hermann Schindelin, Stephen J. Moss

    Publicat 2018
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  16. 16
    Selective Inhibition of KCC2 Leads to Hyperexcitability and Epileptiform Discharges in Hippocampal Slices and<i>In Vivo</i>

    Selective Inhibition of KCC2 Leads to Hyperexcitability and Epileptiform Discharges in Hippocampal Slices and<i>In Vivo</i> per Sudhir Sivakumaran, Ross A. Cardarelli, Jamie Maguire, Matt R. Kelley, Liliya Silayeva, Danielle Morrow, Jayanta Mukherjee, Yvonne E. Moore, Robert J. Mather, Mark E. Duggan, Nicholas J. Brandon, John Dunlop, Stephen Zicha, Stephen J. Moss, Tarek Z. Deeb

    Publicat 2015
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  17. 17
    Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway

    Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway per Jianjia Fan, Rui Qi Zhao, Cameron Parro, Wenchen Zhao, Hsien-Ya Chou, Jérôme Robert, Tarek Z. Deeb, Carina Raynoschek, Samantha Barichievy, Ola Engkvist, Marcello Maresca, Ryan Hicks, Johan Meuller, Stephen J. Moss, Nicholas J. Brandon, Michael W. Wood, Iva Kulić, Cheryl L. Wellington

    Publicat 2018
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  18. 18
    Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation

    Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation per Junko Odajima, Zachary P. Wills, Yasmine Ndassa, Miho Terunuma, Karla Kretschmannova, Tarek Z. Deeb, Yan Geng, Sylwia Gawrzak, Isabel M. Quadros, Jennifer Newman, Manjusri Das, Marie Jecrois, Qunyan Yu, Na Li, Frédéric Bienvenu, Stephen J. Moss, Michael E. Greenberg, Jarrod A. Marto, Piotr Siciński

    Publicat 2011
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  19. 19
    Molecular architecture of potassium chloride co-transporter KCC2

    Molecular architecture of potassium chloride co-transporter KCC2 per Morgane Agez, Patrick Schultz, Igor Medina, David John Baker, Matthew Burnham, Ross A. Cardarelli, Leslie Conway, Kelly Garnier, Stefan Geschwindner, Anders Gunnarsson, Eileen McCall, Alexandre Frechard, Stéphane Audebert, Tarek Z. Deeb, Stephen J. Moss, Nicholas J. Brandon, Qi Wang, Niek Dekker, Anass Jawhari

    Publicat 2017
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  20. 20
    Genetically encoded impairment of neuronal <scp>KCC</scp> 2 cotransporter function in human idiopathic generalized epilepsy

    Genetically encoded impairment of neuronal <scp>KCC</scp> 2 cotransporter function in human idiopathic generalized epilepsy per Kristopher T. Kahle, Nancy D. Merner, Perrine Friedel, Liliya Silayeva, Bo Liang, Arjun Khanna, Yuze Shang, Pamela Lachance‐Touchette, Cynthia V. Bourassa, Annie Levert, Patrick A. Dion, Brian P. Walcott, Dan Spiegelman, Alexandre Dionne‐Laporte, Alan Hodgkinson, Philip Awadalla, Hamid Nikbakht, Jacek Majewski, Patrick Cossette, Tarek Z. Deeb, Stephen J. Moss, Igor Medina, Guy A. Rouleau

    Publicat 2014
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