Resultats de la cerca - Takaya Moriyama

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  1. 1
    Inherited genetic variation in childhood acute lymphoblastic leukemia

    Inherited genetic variation in childhood acute lymphoblastic leukemia per Takaya Moriyama, Mary V. Relling, Jun J. Yang

    Publicat 2015
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  2. 2
    The effects of inherited NUDT15 polymorphisms on thiopurine active metabolites in Japanese children with acute lymphoblastic leukemia

    The effects of inherited NUDT15 polymorphisms on thiopurine active metabolites in Japanese children with acute lymphoblastic leukemia per Takaya Moriyama, Rina Nishii, Ting-Nien Lin, Kentaro Kihira, Hidemi Toyoda, Jacob Nersting, Motohiro Kato, Katsuyoshi Koh, Hiroto Inaba, Atsushi Manabe, Kjeld Schmiegelow, Jun J. Yang, Hiroki Hori

    Publicat 2017
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  3. 3
    Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry

    Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry per Takaya Moriyama, Yung‐Li Yang, Rina Nishii, Hany Ariffin, Chengcheng Liu, Ting-Nien Lin, Wenjian Yang, Dong‐Tsamn Lin, Chih‐Hsiang Yu, Shirley Kow Yin Kham, Ching‐Hon Pui, William E. Evans, Sima Jeha, Mary V. Relling, Allen Eng Juh Yeoh, Jun J. Yang

    Publicat 2017
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  4. 4
    A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology

    A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology per Eric A. Hungate, Sapana Vora, Eric R. Gamazon, Takaya Moriyama, Timothy Best, Imge Hulur, Young‐Hee Lee, Tiffany‐Jane Evans, Eva Ellinghaus, Martin Stanulla, Jérémie Rudant, Laurent Orsi, Jacqueline Clavel, Elizabeth Milne, Rodney J. Scott, Ching‐Hon Pui, Nancy J. Cox, Mignon L. Loh, Jun J. Yang, Andrew D. Skol, Kenan Onel

    Publicat 2016
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  5. 5
    Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy

    Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy per Rina Nishii, Takaya Moriyama, Laura J. Janke, Wenjian Yang, Chase C. Suiter, Ting-Nien Lin, Lie Li, Kentaro Kihira, Hidemi Toyoda, Ute Hofmann, Matthias Schwab, Masatoshi Takagi, Tomohiro Morio, Atsushi Manabe, Shirley Kow Yin Kham, Nan Jiang, Karen R. Rabin, Motohiro Kato, Katsuyoshi Koh, Allen Eng Juh Yeoh, Hiroki Hori, Jun J. Yang

    Publicat 2018
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  6. 6
    Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of <i>EP300</i> and <i>CREBBP</i>

    Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of <i>EP300</i> and <i>CREBBP</i> per Maoxiang Qian, Hui Zhang, Shirley Kow‐Yin Kham, Shuguang Liu, Chuang Jiang, Xujie Zhao, Yi Lü, Charnise Goodings, Ting-Nien Lin, Ranran Zhang, Takaya Moriyama, Zhaohong Yin, Zhenhua Li, Thuan Chong Quah, Hany Ariffin, Ah Moy Tan, Shuhong Shen, Deepa Bhojwani, Shaoyan Hu, Suning Chen, Huyong Zheng, Ching‐Hon Pui, Allen Eng Juh Yeoh, Jun J. Yang

    Publicat 2016
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  7. 7
    Molecular basis of <i>ETV6</i>-mediated predisposition to childhood acute lymphoblastic leukemia

    Molecular basis of <i>ETV6</i>-mediated predisposition to childhood acute lymphoblastic leukemia per Rina Nishii, Rebekah Baskin-Doerfler, Wentao Yang, Ninad Oak, Xujie Zhao, Wenjian Yang, Keito Hoshitsuki, Mackenzie Bloom, Katherine Verbist, Melissa Burns, Zhenhua Li, Ting-Nien Lin, Maoxiang Qian, Takaya Moriyama, Julie M. Gastier‐Foster, Karen R. Rabin, Elizabeth A. Raetz, Charles G. Mullighan, Ching‐Hon Pui, Allen Eng Juh Yeoh, Jinghui Zhang, Monika L. Metzger, Jeffery M. Klco, Stephen P. Hunger, Scott Newman, Gang Wu, Mignon L. Loh, Kim E. Nichols, Jun J. Yang

    Publicat 2020
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  8. 8
    Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study

    Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study per Takaya Moriyama, Monika L. Metzger, Gang Wu, Rina Nishii, Maoxiang Qian, Meenakshi Devidas, Wenjian Yang, Cheng Cheng, Xueyuan Cao, Emily A. Quinn, Susana C. Raimondi, Julie M. Gastier‐Foster, Elizabeth A. Raetz, Eric Larsen, Paul L. Martin, W. Paul Bowman, Naomi J. Winick, Yoshihiro Komada, Shuoguo Wang, Michael N. Edmonson, Heng Xu, Elaine R. Mardis, Robert S. Fulton, Ching‐Hon Pui, Charles G. Mullighan, William E. Evans, Jinghui Zhang, Stephen P. Hunger, Mary V. Relling, Kim E. Nichols, Mignon L. Loh, Jun J. Yang

    Publicat 2015
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  9. 9
    NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity

    NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity per Takaya Moriyama, Rina Nishii, Virginia Pérez-Andreu, Wenjian Yang, Federico Antillón‐Klussmann, Xujie Zhao, Ting-Nien Lin, Keito Hoshitsuki, Jacob Nersting, Kentaro Kihira, Ute Hofmann, Yoshihiro Komada, Motohiro Kato, J. Robert McCorkle, Lie Li, Katsuyoshi Koh, Cesar Najera, Shirley Kow‐Yin Kham, Tomoya Isobe, Zhiwei Chen, Edwynn Kean-Hui Chiew, Deepa Bhojwani, Cynthia Jeffries, Yan Lu, Matthias Schwab, Hiroto Inaba, Ching‐Hon Pui, Mary V. Relling, Atsushi Manabe, Hiroki Hori, Kjeld Schmiegelow, Allen Eng Juh Yeoh, William E. Evans, Jun J. Yang

    Publicat 2016
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  10. 10
    <i>TP53</i> Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children

    <i>TP53</i> Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children per Maoxiang Qian, Xueyuan Cao, Meenakshi Devidas, Wenjian Yang, Cheng Cheng, Yunfeng Dai, Andrew J. Carroll, Nyla A. Heerema, Hui Zhang, Takaya Moriyama, Julie M. Gastier‐Foster, Heng Xu, Elizabeth A. Raetz, Eric Larsen, Naomi J. Winick, W. Paul Bowman, Paul L. Martin, Elaine R. Mardis, Robert S. Fulton, Gerard P. Zambetti, Michael J. Borowitz, Brent L. Wood, Kim E. Nichols, William L. Carroll, Ching‐Hon Pui, Charles G. Mullighan, William E. Evans, Stephen P. Hunger, Mary V. Relling, Mignon L. Loh, Jun J. Yang

    Publicat 2018
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  11. 11
    Massively parallel variant characterization identifies<i>NUDT15</i>alleles associated with thiopurine toxicity

    Massively parallel variant characterization identifies<i>NUDT15</i>alleles associated with thiopurine toxicity per Chase C. Suiter, Takaya Moriyama, Kenneth A. Matreyek, Wentao Yang, Emma Rose Scaletti, Rina Nishii, Wenjian Yang, Keito Hoshitsuki, Minu Singh, Amita Trehan, Christopher R. Parish, Colton Smith, Lie Li, Deepa Bhojwani, Liz Y. P. Yuen, Chi Kong Li, Chak-Ho Li, Yung‐Li Yang, G Walker, James Goodhand, Nicholas A. Kennedy, Federico Antillón‐Klussmann, Smita Bhatia, Mary V. Relling, Motohiro Kato, Hiroki Hori, Prateek Bhatia, Tariq Ahmad, Allen Eng Juh Yeoh, Pål Stenmark, Douglas M. Fowler, Jun J. Yang

    Publicat 2020
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