Kết quả tìm kiếm - Takashi Yoshinaga

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  1. 1
    Development of torsadogenic risk assessment using human induced pluripotent stem cell-derived cardiomyocytes: Japan iPS Cardiac Safety Assessment (JiCSA) update

    Development of torsadogenic risk assessment using human induced pluripotent stem cell-derived cardiomyocytes: Japan iPS Cardiac Safety Assessment (JiCSA) update Bằng Yasunari Kanda, Daiju Yamazaki, Tomoharu Osada, Takashi Yoshinaga, Kohei Sawada

    Được phát hành 2018
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  2. 2
    Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator

    Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator Bằng Junichi Okada, Takashi Yoshinaga, Junko Kurokawa, Takumi Washio, Tetsushi Furukawa, Kohei Sawada, Seiryo Sugiura, Toshiaki Hisada

    Được phát hành 2015
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    Artigo
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  3. 3
    Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential

    Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential Bằng Wataru Yamamoto, Keiichi Asakura, Hiroyuki Ando, Tomohiko Taniguchi, Atsuko Ojima, Takaaki Uda, Tomoharu Osada, Seiji Hayashi, Chieko Kasai, Norimasa Miyamoto, Hiroyuki Tashibu, Takashi Yoshinaga, Daiju Yamazaki, Atsushi Sugiyama, Yasunari Kanda, Kohei Sawada, Yuko Sekino

    Được phát hành 2016
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    Artigo
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  4. 4
    Functional disorders of the sympathetic nervous system in mice lacking the α <sub>1B</sub> subunit (Ca <sub>v</sub> 2.2) of N-type calcium channels

    Functional disorders of the sympathetic nervous system in mice lacking the α <sub>1B</sub> subunit (Ca <sub>v</sub> 2.2) of N-type calcium channels Bằng Mitsuhiro Ino, Takashi Yoshinaga, Minoru Wakamori, Norimasa Miyamoto, Eiki Takahashi, Jiro Sonoda, Takaki Kagaya, Tohru Oki, Takeshi Nagasu, Yukio Nishizawa, Isao Tanaka, Keiji Imoto, Shinichi Aizawa, Sheryl E. Koch, Arnold Schwartz, Tetsuhiro Niidome, Kohei Sawada, Yasuo Mori

    Được phát hành 2001
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    Artigo
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  5. 5
    A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes

    A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes Bằng Hiroyuki Ando, Takashi Yoshinaga, Wataru Yamamoto, Keiichi Asakura, Takaaki Uda, Tomohiko Taniguchi, Atsuko Ojima, Raku Shinkyo, Kiyomi Kikuchi, Tomoharu Osada, Seiji Hayashi, Chieko Kasai, Norimasa Miyamoto, Hiroyuki Tashibu, Daiju Yamazaki, Atsushi Sugiyama, Yasunari Kanda, Kohei Sawada, Yuko Sekino

    Được phát hành 2016
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    Artigo
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  6. 6
    Macrophage-Derived Angiopoietin-Like Protein 2 Accelerates Development of Abdominal Aortic Aneurysm

    Macrophage-Derived Angiopoietin-Like Protein 2 Accelerates Development of Abdominal Aortic Aneurysm Bằng Hirokazu Tazume, Keishi Miyata, Zhe Tian, Motoyoshi Endo, Haruki Horiguchi, Otowa Takahashi, Eiji Horio, Hiroto Tsukano, Tsuyoshi Kadomatsu, Yukiko Nakashima, Ryuji Kunitomo, Yasushi Kaneko, Shuji Moriyama, Hisashi Sakaguchi, Ken Okamoto, Masahiko Hara, Takashi Yoshinaga, Koichi Yoshimura, Hiroki Aoki, Kimi Araki, Hiroyuki Hao, Michio Kawasuji, Yuichi Oike

    Được phát hành 2012
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    Artigo
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  7. 7
    Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective

    Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective Bằng Hugo M. Vargas, Michael G. Rolf, Todd Wisialowski, William E. Achanzar, Anthony Bahinski, Alan Bass, Charles T. Benson, Khuram W. Chaudhary, Nicolas Couvreur, Corina Dota, Michael J. Engwall, C. Michael Foley, David J. Gallacher, Andrea Greiter‐Wilke, Jean‐Michel Guillon, Brian D. Guth, Herbert M. Himmel, Christa Hegele‐Hartung, Maki Ito, Stephen Jenkinson, Katsuyoshi Chiba, Armando Lagrutta, Paul Lévesque, Eric Martel, Yoshiko Okai, Ravikumar Peri, Amy Pointon, Yusheng Qu, Ard Teisman, Martin Traebert, Takashi Yoshinaga, Gary A. Gintant, Derek J. Leishman, Jean‐Pierre Valentin

    Được phát hành 2020
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  8. 8
    General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA <i>In Silico</i> Strategy

    General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA <i>In Silico</i> Strategy Bằng Zhihua Li, Gary R. Mirams, Takashi Yoshinaga, Bradley J. Ridder, Xiaomei Han, Janell E. Chen, Norman Stockbridge, Todd Wisialowski, Bruce P. Damiano, Stefano Severi, Pierre Morissette, Peter R. Kowey, Mark Holbrook, Godfrey L. Smith, Randall L. Rasmusson, Michael Liu, Zhen Song, Zhilin Qu, Derek J. Leishman, Jill Steidl‐Nichols, Blanca Rodríguez, Alfonso Bueno‐Orovio, Xin Zhou, Elisa Passini, Andrew G. Edwards, Stefano Morotti, Haibo Ni, Eleonora Grandi, Colleen E. Clancy, Jamie I. Vandenberg, Adam P. Hill, Mikiko Nakamura, Thomas P. Singer, Liudmila Polonchuk, Andrea Greiter‐Wilke, Ken Wang, Stephane Navé, Aaron Fullerton, Eric A. Sobie, Michelangelo Paci, Flora T. Musuamba, David G. Strauss

    Được phát hành 2019
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    Artigo
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  9. 9
    Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

    Diversity-oriented synthesis yields novel multistage antimalarial inhibitors Bằng Nobutaka Kato, Eamon Comer, Tomoyo Sakata‐Kato, Arvind Sharma, Manmohan Sharma, Micah Maetani, Jessica Bastien, Nicolas M. B. Brancucci, Joshua A. Bittker, Victoria Corey, David C. Clarke, Emily R. Derbyshire, Gillian L. Dornan, Sandra Duffy, Sean Eckley, Maurice A. Itoe, Karin M. J. Koolen, Timothy A. Lewis, Ping S. Lui, Amanda K. Lukens, Emily Lund, Sandra March, Elamaran Meibalan, Bennett C. Meier, Jacob A. McPhail, Branko Mitasev, Eli L. Moss, Morgane Sayes, Yvonne Van Gessel, Mathias J. Wawer, Takashi Yoshinaga, Anne‐Marie Zeeman, Vicky M. Avery, Sangeeta N. Bhatia, John E. Burke, Flaminia Catteruccia, Jon Clardy, Paul A. Clemons, Koen J. Dechering, Jeremy R. Duvall, Michael A. Foley, Fabian Gusovsky, Clemens H. M. Kocken, Matthias Marti, Marshall Morningstar, Benito Muñoz, Daniel E. Neafsey, Amit Sharma, Elizabeth A. Winzeler, Dyann F. Wirth, Christina Scherer, Stuart L. Schreiber

    Được phát hành 2016
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    Artigo
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