Ngā hua rapu kaituhi :: APM

1

Silencing of HSP90 Cochaperone AHA1 Expression Decreases Client Protein Activation and Increases Cellular Sensitivity to the HSP90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin mā Joanna L. Holmes, Swee Y. Sharp, Steve Hobbs, Paul Workman

I whakaputaina 2008

Whiwhi kuputuhi katoa
Artigo

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2

BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma mā Philip Beale, Paul Rogers, Frances Boxall, Swee Y. Sharp, LR Kelland

I whakaputaina 2000

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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3

DT-Diaphorase Expression and Tumor Cell Sensitivity to 17-Allylamino,17-demethoxygeldanamycin, an Inhibitor of Heat Shock Protein 90 mā LR Kelland, Swee Y. Sharp, Paul Rogers, Timothy G. Myers, Paul Workman

I whakaputaina 1999

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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4

In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473 mā J Holford, Swee Y. Sharp, Barry A. Murrer, Michael J. Abrams, Lloyd R. Kèlland

I whakaputaina 1998

Whiwhi kuputuhi katoa
Artigo

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5

Mechanistic Evaluation of the Novel HSP90 Inhibitor NVP-AUY922 in Adult and Pediatric Glioblastoma mā Nathalie Gaspar, Swee Y. Sharp, Suzanne A. Eccles, Sharon Gowan, Sergey Popov, Chris Jones, Andrew D.J. Pearson, Gilles Vassal, Paul Workman

I whakaputaina 2010

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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6

Acquired Resistance to 17-Allylamino-17-Demethoxygeldanamycin (17-AAG, Tanespimycin) in Glioblastoma Cells mā Nathalie Gaspar, Swee Y. Sharp, Simon Pacey, Chris Jones, Michael I. Walton, Gilles Vassal, Suzanne A. Eccles, Andrew D.J. Pearson, Paul Workman

I whakaputaina 2009

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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7

MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase–Mediated <i>HOX</i>/Stem Cell Gene Signature mā Nathalie Gaspar, Lynley V. Marshall, Lara Perryman, Dorine A. Bax, Suzanne E. Little, Marta Viana‐Pereira, Swee Y. Sharp, Gilles Vassal, Andrew D.J. Pearson, Rui Manuel Reis, Darren Hargrave, Paul Workman, Chris Jones

I whakaputaina 2010

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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8

Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766) mā N. Chessum, Swee Y. Sharp, John Caldwell, Elisa Pasqua, Birgit Wilding, Giampiero Colombano, Ian Collins, Buǧra Özer, Meirion Richards, Martin Rowlands, Mark Stubbs, Rosemary Burke, Craig McAndrew, Paul A. Clarke, Paul Workman, Matthew D. Cheeseman, Keith Jones

I whakaputaina 2017

Whiwhi kuputuhi katoa
Artigo

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9

Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms mā Lisa Wright, Xavier Barril, Brian Dymock, Louisa Sheridan, A.E. Surgenor, Mandy Beswick, Martin J. Drysdale, Adam J. Collier, Andy Massey, Nicholas G. Davies, Alex Fink, Christophe Fromont, Wynne Aherne, Kathy Boxall, Swee Y. Sharp, Paul Workman, Roderick E. Hubbard

I whakaputaina 2004

Whiwhi kuputuhi katoa
Artigo

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10

The Association of CCND1 Overexpression and Cisplatin Resistance in Testicular Germ Cell Tumors and Other Cancers mā Elodie Noël, Marc Yeste‐Velasco, Xueying Mao, Jackie Perry, Sakunthala C. Kudahetti, Ningfeng Fiona Li, Swee Y. Sharp, Tracy Chaplin, Liyan Xue, Alan McIntyre, Ling Shan, Thomas Powles, R.T.D. Oliver, Bryan D. Young, Janet Shipley, Daniel M. Berney, Simon P. Joel, Yong‐Jie Lu

I whakaputaina 2010

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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11

Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells mā Roberta Ferraldeschi, Jonathan Welti, Marissa Powers, Wei Yuan, Tomoko Smyth, George Seed, Ruth Riisnaes, Somaieh Hedayat, Hannah Wang, Mateus Crespo, Daniel Nava Rodrigues, Ines Figueiredo, Susana Miranda, Suzanne Carreira, John F. Lyons, Swee Y. Sharp, Stephen R. Plymate, Gerhardt Attard, Nicola G. Wallis, Paul Workman, Johann S. de Bono

I whakaputaina 2016

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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12

Gene and Protein Expression Profiling of Human Ovarian Cancer Cells Treated with the Heat Shock Protein 90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin mā Alison Maloney, Paul A. Clarke, Søren Naaby‐Hansen, Robert C. Stein, Jens-Oliver Koopman, Akunna Akpan, Alice Yang, Marketa Zvelebil, Rainer Cramer, Lindsay Stimson, Wynne Aherne, Udai Banerji, Ian Judson, Swee Y. Sharp, Marissa Powers, Emmanuel de Billy, Joanne Salmons, Michael I. Walton, A. L. Burlingame, Michael Waterfield, Paul Workman

I whakaputaina 2007

Whiwhi kuputuhi katoa
Artigo

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13

EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines mā Dorine A. Bax, Nathalie Gaspar, Suzanne E. Little, Lynley V. Marshall, Lara Perryman, Marie Regairaz, Marta Viana‐Pereira, Raisa Vuononvirta, Swee Y. Sharp, Jorge S. Reis‐Filho, João N. Stávale, Safa Al‐Sarraj, Rui Manuel Reis, Gilles Vassal, Andrew D.J. Pearson, Darren Hargrave, David W. Ellison, Paul Workman, Chris Jones

I whakaputaina 2009

Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
Artigo

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14

Data from EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines mā Dorine A. Bax, Nathalie Gaspar, Suzanne E. Little, Lynley V. Marshall, Lara Perryman, Marie Regairaz, Marta Viana‐Pereira, Raisa Vuononvirta, Swee Y. Sharp, Jorge S. Reis‐Filho, João Norberto Stávale, Safa Al‐Sarraj, Rui Manuel Reis, Gilles Vassal, Andrew D.J. Pearson, Darren Hargrave, David W. Ellison, Paul Workman, Chris Jones

I whakaputaina 2023

Whiwhi kuputuhi katoa
Pré-impressão

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15

<i>In vitro</i> Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors mā Swee Y. Sharp, Kathy Boxall, Martin Rowlands, Chrisostomos Prodromou, S. Mark Roe, Alison Maloney, Marissa Powers, Paul A. Clarke, Gary Box, Sharon Sanderson, Lisa Patterson, Thomas P. Matthews, Kwai-Ming J. Cheung, Karen Ball, Angela Hayes, Florence I. Raynaud, Richard Marais, Laurence H. Pearl, Sue Eccles, Wynne Aherne, Edward McDonald, Paul Workman

I whakaputaina 2007

Whiwhi kuputuhi katoa
Artigo

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16

$HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies$

HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies mā Elisa Pasqua, Swee Y. Sharp, N. Chessum, Angela Hayes, Loredana Pellegrino, Michael Tucker, Asadh Miah, Birgit Wilding, Lindsay E. Evans, Carl S. Rye, N. Yi Mok, Manjuan Liu, Alan T. Henley, Sharon Gowan, Emmanuel de Billy, Robert te Poele, Marissa Powers, Suzanne A. Eccles, Paul A. Clarke, Florence I. Raynaud, Paul Workman, Keith Jones, Matthew D. Cheeseman

I whakaputaina 2023

Whiwhi kuputuhi katoa
Artigo

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17

Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen mā Matthew D. Cheeseman, N. Chessum, Carl S. Rye, Elisa Pasqua, Michael Tucker, Birgit Wilding, Lindsay E. Evans, Susan Lepri, Meirion Richards, Swee Y. Sharp, Salyha Ali, Martin Rowlands, Lisa O’Fee, Asadh Miah, Angela Hayes, Alan T. Henley, Marissa Powers, Robert te Poele, Emmanuel de Billy, Loredana Pellegrino, Florence I. Raynaud, Rosemary Burke, Rob L. M. van Montfort, Suzanne A. Eccles, Paul Workman, Keith Jones

I whakaputaina 2016

Whiwhi kuputuhi katoa
Artigo

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18

Inhibition of the heat shock protein 90 molecular chaperone <i>in vitro</i> and <i>in vivo</i> by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues mā Swee Y. Sharp, Chrisostomos Prodromou, Kathy Boxall, Marissa Powers, Joanna L. Holmes, Gary Box, Thomas P. Matthews, Kwai-Ming J. Cheung, Andrew Kalusa, Karen James, Angela Hayes, Anthea Hardcastle, Brian Dymock, Paul A. Brough, Xavier Barril, Julie E. Cansfield, Lisa Wright, A.E. Surgenor, Nicolas Foloppe, Roderick E. Hubbard, Wynne Aherne, Laurence H. Pearl, Keith Jones, Edward McDonald, Florence I. Raynaud, Sue Eccles, Martin J. Drysdale, Paul Workman

I whakaputaina 2007

Whiwhi kuputuhi katoa
Artigo

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19

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis mā Suzanne A. Eccles, Andy Massey, Florence I. Raynaud, Swee Y. Sharp, Gary Box, Melanie Valenti, Lisa Patterson, Alexis de Haven Brandon, Sharon Gowan, Frances Boxall, Wynne Aherne, Martin Rowlands, Angela Hayes, Vanessa Martins, Frederique Urban, Kathy Boxall, Chrisostomos Prodromou, Laurence H. Pearl, Karen James, Thomas P. Matthews, Kwai-Ming J. Cheung, Andrew Kalusa, Keith Jones, Edward McDonald, Xavier Barril, Paul A. Brough, Julie E. Cansfield, Brian Dymock, Martin J. Drysdale, Harry Finch, Rob Howes, Roderick E. Hubbard, Alan Surgenor, Paul Webb, Mike Wood, Lisa Wright, Paul Workman

I whakaputaina 2008

Whiwhi kuputuhi katoa
Artigo

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