Výsledky vyhledávání - Swee Y. Sharp

  • Zobrazuji výsledky 1 - 19 z 19
Upřesnit hledání
  1. 1
    Silencing of HSP90 Cochaperone AHA1 Expression Decreases Client Protein Activation and Increases Cellular Sensitivity to the HSP90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin

    Silencing of HSP90 Cochaperone AHA1 Expression Decreases Client Protein Activation and Increases Cellular Sensitivity to the HSP90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin Autor Joanna L. Holmes, Swee Y. Sharp, Steve Hobbs, Paul Workman

    Vydáno 2008
    Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  2. 2
    BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma

    BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma Autor Philip Beale, Paul Rogers, Frances Boxall, Swee Y. Sharp, LR Kelland

    Vydáno 2000
    Získat plný text Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  3. 3
    DT-Diaphorase Expression and Tumor Cell Sensitivity to 17-Allylamino,17-demethoxygeldanamycin, an Inhibitor of Heat Shock Protein 90

    DT-Diaphorase Expression and Tumor Cell Sensitivity to 17-Allylamino,17-demethoxygeldanamycin, an Inhibitor of Heat Shock Protein 90 Autor LR Kelland, Swee Y. Sharp, Paul Rogers, Timothy G. Myers, Paul Workman

    Vydáno 1999
    Získat plný text Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  4. 4
    In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473

    In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473 Autor J Holford, Swee Y. Sharp, Barry A. Murrer, Michael J. Abrams, Lloyd R. Kèlland

    Vydáno 1998
    Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  5. 5
    Mechanistic Evaluation of the Novel HSP90 Inhibitor NVP-AUY922 in Adult and Pediatric Glioblastoma

    Mechanistic Evaluation of the Novel HSP90 Inhibitor NVP-AUY922 in Adult and Pediatric Glioblastoma Autor Nathalie Gaspar, Swee Y. Sharp, Suzanne A. Eccles, Sharon Gowan, Sergey Popov, Chris Jones, Andrew D.J. Pearson, Gilles Vassal, Paul Workman

    Vydáno 2010
    Získat plný text Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  6. 6
    Acquired Resistance to 17-Allylamino-17-Demethoxygeldanamycin (17-AAG, Tanespimycin) in Glioblastoma Cells

    Acquired Resistance to 17-Allylamino-17-Demethoxygeldanamycin (17-AAG, Tanespimycin) in Glioblastoma Cells Autor Nathalie Gaspar, Swee Y. Sharp, Simon Pacey, Chris Jones, Michael I. Walton, Gilles Vassal, Suzanne A. Eccles, Andrew D.J. Pearson, Paul Workman

    Vydáno 2009
    Získat plný text Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  7. 7
    MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase–Mediated <i>HOX</i>/Stem Cell Gene Signature

    MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase–Mediated <i>HOX</i>/Stem Cell Gene Signature Autor Nathalie Gaspar, Lynley V. Marshall, Lara Perryman, Dorine A. Bax, Suzanne E. Little, Marta Viana‐Pereira, Swee Y. Sharp, Gilles Vassal, Andrew D.J. Pearson, Rui Manuel Reis, Darren Hargrave, Paul Workman, Chris Jones

    Vydáno 2010
    Získat plný text Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  8. 8
    Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766)

    Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766) Autor N. Chessum, Swee Y. Sharp, John Caldwell, Elisa Pasqua, Birgit Wilding, Giampiero Colombano, Ian Collins, Buǧra Özer, Meirion Richards, Martin Rowlands, Mark Stubbs, Rosemary Burke, Craig McAndrew, Paul A. Clarke, Paul Workman, Matthew D. Cheeseman, Keith Jones

    Vydáno 2017
    Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  9. 9
    Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms

    Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms Autor Lisa Wright, Xavier Barril, Brian Dymock, Louisa Sheridan, A.E. Surgenor, Mandy Beswick, Martin J. Drysdale, Adam J. Collier, Andy Massey, Nicholas G. Davies, Alex Fink, Christophe Fromont, Wynne Aherne, Kathy Boxall, Swee Y. Sharp, Paul Workman, Roderick E. Hubbard

    Vydáno 2004
    Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  10. 10
    The Association of CCND1 Overexpression and Cisplatin Resistance in Testicular Germ Cell Tumors and Other Cancers

    The Association of CCND1 Overexpression and Cisplatin Resistance in Testicular Germ Cell Tumors and Other Cancers Autor Elodie Noël, Marc Yeste‐Velasco, Xueying Mao, Jackie Perry, Sakunthala C. Kudahetti, Ningfeng Fiona Li, Swee Y. Sharp, Tracy Chaplin, Liyan Xue, Alan McIntyre, Ling Shan, Thomas Powles, R.T.D. Oliver, Bryan D. Young, Janet Shipley, Daniel M. Berney, Simon P. Joel, Yong‐Jie Lu

    Vydáno 2010
    Získat plný text Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  11. 11
    Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells

    Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells Autor Roberta Ferraldeschi, Jonathan Welti, Marissa Powers, Wei Yuan, Tomoko Smyth, George Seed, Ruth Riisnaes, Somaieh Hedayat, Hannah Wang, Mateus Crespo, Daniel Nava Rodrigues, Ines Figueiredo, Susana Miranda, Suzanne Carreira, John F. Lyons, Swee Y. Sharp, Stephen R. Plymate, Gerhardt Attard, Nicola G. Wallis, Paul Workman, Johann S. de Bono

    Vydáno 2016
    Získat plný text Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  12. 12
    Gene and Protein Expression Profiling of Human Ovarian Cancer Cells Treated with the Heat Shock Protein 90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin

    Gene and Protein Expression Profiling of Human Ovarian Cancer Cells Treated with the Heat Shock Protein 90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin Autor Alison Maloney, Paul A. Clarke, Søren Naaby‐Hansen, Robert C. Stein, Jens-Oliver Koopman, Akunna Akpan, Alice Yang, Marketa Zvelebil, Rainer Cramer, Lindsay Stimson, Wynne Aherne, Udai Banerji, Ian Judson, Swee Y. Sharp, Marissa Powers, Emmanuel de Billy, Joanne Salmons, Michael I. Walton, A. L. Burlingame, Michael Waterfield, Paul Workman

    Vydáno 2007
    Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  13. 13
    EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines

    EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines Autor Dorine A. Bax, Nathalie Gaspar, Suzanne E. Little, Lynley V. Marshall, Lara Perryman, Marie Regairaz, Marta Viana‐Pereira, Raisa Vuononvirta, Swee Y. Sharp, Jorge S. Reis‐Filho, João N. Stávale, Safa Al‐Sarraj, Rui Manuel Reis, Gilles Vassal, Andrew D.J. Pearson, Darren Hargrave, David W. Ellison, Paul Workman, Chris Jones

    Vydáno 2009
    Získat plný text Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  14. 14
    Data from EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines

    Data from EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines Autor Dorine A. Bax, Nathalie Gaspar, Suzanne E. Little, Lynley V. Marshall, Lara Perryman, Marie Regairaz, Marta Viana‐Pereira, Raisa Vuononvirta, Swee Y. Sharp, Jorge S. Reis‐Filho, João Norberto Stávale, Safa Al‐Sarraj, Rui Manuel Reis, Gilles Vassal, Andrew D.J. Pearson, Darren Hargrave, David W. Ellison, Paul Workman, Chris Jones

    Vydáno 2023
    Získat plný text
    Pré-impressão
    Přidat do oblíbených
    Uloženo v:
  15. 15
    <i>In vitro</i> Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors

    <i>In vitro</i> Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors Autor Swee Y. Sharp, Kathy Boxall, Martin Rowlands, Chrisostomos Prodromou, S. Mark Roe, Alison Maloney, Marissa Powers, Paul A. Clarke, Gary Box, Sharon Sanderson, Lisa Patterson, Thomas P. Matthews, Kwai-Ming J. Cheung, Karen Ball, Angela Hayes, Florence I. Raynaud, Richard Marais, Laurence H. Pearl, Sue Eccles, Wynne Aherne, Edward McDonald, Paul Workman

    Vydáno 2007
    Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  16. 16
    HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies

    HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies Autor Elisa Pasqua, Swee Y. Sharp, N. Chessum, Angela Hayes, Loredana Pellegrino, Michael Tucker, Asadh Miah, Birgit Wilding, Lindsay E. Evans, Carl S. Rye, N. Yi Mok, Manjuan Liu, Alan T. Henley, Sharon Gowan, Emmanuel de Billy, Robert te Poele, Marissa Powers, Suzanne A. Eccles, Paul A. Clarke, Florence I. Raynaud, Paul Workman, Keith Jones, Matthew D. Cheeseman

    Vydáno 2023
    Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  17. 17
    Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen

    Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen Autor Matthew D. Cheeseman, N. Chessum, Carl S. Rye, Elisa Pasqua, Michael Tucker, Birgit Wilding, Lindsay E. Evans, Susan Lepri, Meirion Richards, Swee Y. Sharp, Salyha Ali, Martin Rowlands, Lisa O’Fee, Asadh Miah, Angela Hayes, Alan T. Henley, Marissa Powers, Robert te Poele, Emmanuel de Billy, Loredana Pellegrino, Florence I. Raynaud, Rosemary Burke, Rob L. M. van Montfort, Suzanne A. Eccles, Paul Workman, Keith Jones

    Vydáno 2016
    Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  18. 18
    Inhibition of the heat shock protein 90 molecular chaperone <i>in vitro</i> and <i>in vivo</i> by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues

    Inhibition of the heat shock protein 90 molecular chaperone <i>in vitro</i> and <i>in vivo</i> by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues Autor Swee Y. Sharp, Chrisostomos Prodromou, Kathy Boxall, Marissa Powers, Joanna L. Holmes, Gary Box, Thomas P. Matthews, Kwai-Ming J. Cheung, Andrew Kalusa, Karen James, Angela Hayes, Anthea Hardcastle, Brian Dymock, Paul A. Brough, Xavier Barril, Julie E. Cansfield, Lisa Wright, A.E. Surgenor, Nicolas Foloppe, Roderick E. Hubbard, Wynne Aherne, Laurence H. Pearl, Keith Jones, Edward McDonald, Florence I. Raynaud, Sue Eccles, Martin J. Drysdale, Paul Workman

    Vydáno 2007
    Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:
  19. 19
    NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

    NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis Autor Suzanne A. Eccles, Andy Massey, Florence I. Raynaud, Swee Y. Sharp, Gary Box, Melanie Valenti, Lisa Patterson, Alexis de Haven Brandon, Sharon Gowan, Frances Boxall, Wynne Aherne, Martin Rowlands, Angela Hayes, Vanessa Martins, Frederique Urban, Kathy Boxall, Chrisostomos Prodromou, Laurence H. Pearl, Karen James, Thomas P. Matthews, Kwai-Ming J. Cheung, Andrew Kalusa, Keith Jones, Edward McDonald, Xavier Barril, Paul A. Brough, Julie E. Cansfield, Brian Dymock, Martin J. Drysdale, Harry Finch, Rob Howes, Roderick E. Hubbard, Alan Surgenor, Paul Webb, Mike Wood, Lisa Wright, Paul Workman

    Vydáno 2008
    Získat plný text
    Artigo
    Přidat do oblíbených
    Uloženo v:

Vyhledávací nástroje: