Hakutulokset - Sukumar, Madhusudhanan

The short and sweet of T-cell therapy: Restraining glycolysis enhances the formation of immunological memory and antitumor immune responses Tekijä Sukumar, Madhusudhanan, Gattinoni, Luca

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Nutrient Competition: A New Axis of Tumor Immunosuppression Tekijä Sukumar, Madhusudhanan, Roychoudhuri, Rahul, Restifo, Nicholas P.

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Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy Tekijä Crompton, Joseph G., Sukumar, Madhusudhanan, Restifo, Nicholas P.

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Targeting Akt in cell transfer immunotherapy for cancer Tekijä Crompton, Joseph G, Sukumar, Madhusudhanan, Restifo, Nicholas P

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Metabolic regulation of T cell longevity and function in tumor immunotherapy Tekijä Kishton, Rigel J., Sukumar, Madhusudhanan, Restifo, Nicholas P

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Arginine Arms T Cells to Thrive and Survive Tekijä Kishton, Rigel J., Sukumar, Madhusudhanan, Restifo, Nicholas P.

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Metabolic reprograming of anti-tumor immunity Tekijä Sukumar, Madhusudhanan, Kishton, Rigel J, Restifo, Nicholas P

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Modulating immunometabolism of tumor specific CD8 T cells to enhance T cell based therapy for cancer Tekijä Sukumar, Madhusudhanan, Liu, Jie, Mehta, Gautam, Gattinoni, Luca, Finkel, Toren, Restifo, Nicholas

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Mitochondrial activity regulates T cell memory, self renewal and anti tumor function in CD8+ T cells Tekijä Sukumar, Madhusudhanan, Liu, Jie, Crompton, Joseph, Rao, Mahadev, Ji, Yun, Finkel, Toren, Gattinoni, Luca, Restifo, Nicholas

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Stromal Interferon-γ Signaling and Cross-Presentation Are Required to Eliminate Antigen-Loss Variants of B Cell Lymphomas in Mice Tekijä Gerbitz, Armin, Sukumar, Madhusudhanan, Helm, Florian, Wilke, Andrea, Friese, Christian, Fahrenwaldt, Cornelia, Lehmann, Frank M., Loddenkemper, Christoph, Kammertoens, Thomas, Mautner, Josef, Schmitt, Clemens A., Blankenstein, Thomas, Bornkamm, Georg W.

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Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits CD8(+) T cell memory formation Tekijä Ji, Yun, Pos, Zoltan, Rao, Mahadev, Klebanoff, Christopher A., Yu, Zhiya, Sukumar, Madhusudhanan, Reger, Robert N., Palmer, Douglas C., Borman, Zachary A., Muranski, Pawel, Wang, Ena, Schrump, David S., Marincola, Francesco M., Restifo, Nicholas P., Gattinoni, Luca

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Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells Tekijä Lee, Ping-Hsien, Yamamoto, Tori N., Gurusamy, Devikala, Sukumar, Madhusudhanan, Yu, Zhiya, Hu-Li, Jane, Kawabe, Takeshi, Gangaplara, Arunakumar, Kishton, Rigel J., Henning, Amanda N., Vodnala, Suman K., Germain, Ronald N., Paul, William E., Restifo, Nicholas P.

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Inhibiting glycolytic metabolism enhances CD8(+) T cell memory and antitumor function Tekijä Sukumar, Madhusudhanan, Liu, Jie, Ji, Yun, Subramanian, Murugan, Crompton, Joseph G., Yu, Zhiya, Roychoudhuri, Rahul, Palmer, Douglas C., Muranski, Pawel, Karoly, Edward D., Mohney, Robert P., Klebanoff, Christopher A., Lal, Ashish, Finkel, Toren, Restifo, Nicholas P., Gattinoni, Luca

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miR-155 augments CD8(+) T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γ(c) cytokines Tekijä Ji, Yun, Wrzesinski, Claudia, Yu, Zhiya, Hu, Jinhui, Gautam, Sanjivan, Hawk, Nga V., Telford, William G., Palmer, Douglas C., Franco, Zulmarie, Sukumar, Madhusudhanan, Roychoudhuri, Rahul, Clever, David, Klebanoff, Christopher A., Surh, Charles D., Waldmann, Thomas A., Restifo, Nicholas P., Gattinoni, Luca

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Lineage relationship of CD8(+) T cell subsets is revealed by progressive changes in the epigenetic landscape Tekijä Crompton, Joseph G., Narayanan, Manikandan, Cuddapah, Suresh, Roychoudhuri, Rahul, Ji, Yun, Yang, Wenjing, Patel, Shashank J., Sukumar, Madhusudhanan, Palmer, Douglas C., Peng, Weiqun, Wang, Ena, Marincola, Francesco M., Klebanoff, Christopher A., Zhao, Keji, Tsang, John S., Gattinoni, Luca, Restifo, Nicholas P.

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T cell oxygen-sensing proteins establish an immunologically tolerant metastatic niche Tekijä Clever, David, Roychoudhuri, Rahul, Constantinides, Michael G, Askenase, Michael H, Sukumar, Madhusudhanan, Klebanoff, Christopher A, Eil, Robert L, Hickman, Heather D, Yu, Zhiya, Pan, Jenny H, Palmer, Douglas C, Phan, Anthony T, Goulding, John, Gattinoni, Luca, Goldrath, Ananda W, Belkaid, Yasmine, Restifo, Nicholas P

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Ionic immune suppression within the tumour microenvironment limits T cell effector function Tekijä Eil, Robert, Vodnala, Suman K, Clever, David, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Pan, Jenny H, Palmer, Douglas C, Gros, Alena, Yamamoto, Tori N, Patel, Shashank J, Guittard, Geoffrey C, Yu, Zhiya, Carbonaro, Valentina, Okkenhaug, Klaus, Schrump, David S, Linehan, W Marston, Roychoudhuri, Rahul, Restifo, Nicholas P

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Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy Tekijä Klebanoff, Christopher A., Crompton, Joseph G., Leonardi, Anthony J., Yamamoto, Tori N., Chandran, Smita S., Eil, Robert L., Sukumar, Madhusudhanan, Vodnala, Suman K., Hu, Jinhui, Ji, Yun, Clever, David, Black, Mary A., Gurusamy, Devikala, Kruhlak, Michael J., Jin, Ping, Stroncek, David F., Gattinoni, Luca, Feldman, Steven A., Restifo, Nicholas P.

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T cell stemness and dysfunction in tumors are triggered by a common mechanism Tekijä Vodnala, Suman Kumar, Eil, Robert, Kishton, Rigel J., Sukumar, Madhusudhanan, Yamamoto, Tori N., Ha, Ngoc-Han, Lee, Ping-Hsien, Shin, MinHwa, Patel, Shashank J., Yu, Zhiya, Palmer, Douglas C., Kruhlak, Michael J., Liu, Xiaojing, Locasale, Jason W., Huang, Jing, Roychoudhuri, Rahul, Finkel, Toren, Klebanoff, Christopher A., Restifo, Nicholas P.

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Th17 cells are long-lived and retain a stem cell-like molecular signature Tekijä Muranski, Pawel, Borman, Zachary A., Kerkar, Sid P., Klebanoff, Christopher A., Ji, Yun, Sanchez-Perez, Luis, Sukumar, Madhusudhanan, Reger, Robert N., Yu, Zhiya, Kern, Steven J., Roychoudhuri, Rahul, Ferreyra, Gabriela A., Shen, Wei, Durum, Scott K., Feigenbaum, Lionel, Palmer, Douglas C., Antony, Paul A., Chan, Chi-Chao, Laurence, Arian, Danner, Robert L., Gattinoni, Luca, Restifo, Nicholas P.

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