Ngā hua rapu - Sugiyama, Yuichi

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  1. 1
    Active Efflux across the Blood-Brain Barrier: Role of the Solute Carrier Family

    Active Efflux across the Blood-Brain Barrier: Role of the Solute Carrier Family mā Kusuhara, Hiroyuki, Sugiyama, Yuichi

    I whakaputaina 2005
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  2. 2
    Glutathione S-transferases in elasmobranch liver. Molecular heterogeneity, catalytic and binding properties, and purification

    Glutathione S-transferases in elasmobranch liver. Molecular heterogeneity, catalytic and binding properties, and purification mā Sugiyama, Yuichi, Yamada, Tadataka, Kaplowitz, Neil

    I whakaputaina 1981
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  3. 3
    Prediction of Hepatic Clearance in Human From In Vitro Data for Successful Drug Development

    Prediction of Hepatic Clearance in Human From In Vitro Data for Successful Drug Development mā Chiba, Masato, Ishii, Yasuyuki, Sugiyama, Yuichi

    I whakaputaina 2009
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  4. 4
    Post-translational regulation of the major drug transporters in the families of organic anion transporters and organic anion–transporting polypeptides

    Post-translational regulation of the major drug transporters in the families of organic anion transporters and organic anion–transporting polypeptides mā Lee, Wooin, Ha, Jeong-min, Sugiyama, Yuichi

    I whakaputaina 2020
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  5. 5
    Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P 4503A4

    Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P 4503A4 mā Achira, Meguru, Ito, Kiyomi, Suzuki, Hiroshi, Sugiyama, Yuichi

    I whakaputaina 1999
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  6. 6
    Virtual Clinical Studies to Examine the Probability Distribution of the AUC at Target Tissues Using Physiologically-Based Pharmacokinetic Modeling: Application to Analyses of the Effect of Genetic Polymorphism of Enzymes and Transporters on Irinotecan Induced Side Effects

    Virtual Clinical Studies to Examine the Probability Distribution of the AUC at Target Tissues Using Physiologically-Based Pharmacokinetic Modeling: Application to Analyses of the E... mā Toshimoto, Kota, Tomaru, Atsuko, Hosokawa, Masakiyo, Sugiyama, Yuichi

    I whakaputaina 2017
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  7. 7
    Differences in Substrate Specificity among Glutathione Conjugates (GS‐X) Pump Family Members: Comparison between Multidrug Resistance‐associated Protein and a Novel Transporter Expressed on a Cisplatin‐resistant Cell Line (KCP‐4)

    Differences in Substrate Specificity among Glutathione Conjugates (GS‐X) Pump Family Members: Comparison between Multidrug Resistance‐associated Protein and a Novel Transporter Exp... mā Ueda, Kaoru, Suzuki, Hiroshi, Akiyama, Shin‐ichi, Sugiyama, Yuichi

    I whakaputaina 1999
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  8. 8
    Investigation of the importance of multidrug resistance-associated protein 4 (Mrp4/Abcc4) in the active efflux of anionic drugs across the blood–brain barrier

    Investigation of the importance of multidrug resistance-associated protein 4 (Mrp4/Abcc4) in the active efflux of anionic drugs across the blood–brain barrier mā Kanamitsu, Kayoko, Kusuhara, Hiroyuki, Schuetz, John D., Takeuchi, Kenji, Sugiyama, Yuichi

    I whakaputaina 2017
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  9. 9
    Robust physiologically based pharmacokinetic model of rifampicin for predicting drug–drug interactions via P‐glycoprotein induction and inhibition in the intestine, liver, and kidney

    Robust physiologically based pharmacokinetic model of rifampicin for predicting drug–drug interactions via P‐glycoprotein induction and inhibition in the intestine, liver, and kidn... mā Asaumi, Ryuta, Nunoya, Ken‐ichi, Yamaura, Yoshiyuki, Taskar, Kunal S., Sugiyama, Yuichi

    I whakaputaina 2022
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  10. 10
    Physiologically‐Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter–Mediated Interactions Between Metformin and Cimetidine

    Physiologically‐Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter–Mediated Interactions Between Metformin and Cimetidine mā Nishiyama, Kotaro, Toshimoto, Kota, Lee, Wooin, Ishiguro, Naoki, Bister, Bojan, Sugiyama, Yuichi

    I whakaputaina 2019
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  11. 11
    Decreased Hepatic Breast Cancer Resistance Protein Expression and Function in Multidrug Resistance-Associated Protein 2-Deficient (TR(−)) Rats

    Decreased Hepatic Breast Cancer Resistance Protein Expression and Function in Multidrug Resistance-Associated Protein 2-Deficient (TR(−)) Rats mā Yue, Wei, Lee, Jin Kyung, Abe, Koji, Sugiyama, Yuichi, Brouwer, Kim L. R.

    I whakaputaina 2011
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  12. 12
    Assessment of statin-associated muscle toxicity in Japan: a cohort study conducted using claims database and laboratory information

    Assessment of statin-associated muscle toxicity in Japan: a cohort study conducted using claims database and laboratory information mā Chang, Chia-Hsien, Kusama, Makiko, Ono, Shunsuke, Sugiyama, Yuichi, Orii, Takao, Akazawa, Manabu

    I whakaputaina 2013
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  13. 13
    Application of PBPK Modeling and Virtual Clinical Study Approaches to Predict the Outcomes of CYP2D6 Genotype‐Guided Dosing of Tamoxifen

    Application of PBPK Modeling and Virtual Clinical Study Approaches to Predict the Outcomes of CYP2D6 Genotype‐Guided Dosing of Tamoxifen mā Nakamura, Toshimichi, Toshimoto, Kota, Lee, Wooin, Imamura, Chiyo K., Tanigawara, Yusuke, Sugiyama, Yuichi

    I whakaputaina 2018
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  14. 14
    Expanded Physiologically‐Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion Transporting Polypeptide 1B Induction

    Expanded Physiologically‐Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion... mā Asaumi, Ryuta, Menzel, Karsten, Lee, Wooin, Nunoya, Ken‐ichi, Imawaka, Haruo, Kusuhara, Hiroyuki, Sugiyama, Yuichi

    I whakaputaina 2019
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  15. 15
    Direct and Rapid Genotyping of SLCO1B1 388A>G and 521T>C in Human Blood Specimens Using the SmartAmp-2 Method

    Direct and Rapid Genotyping of SLCO1B1 388A>G and 521T>C in Human Blood Specimens Using the SmartAmp-2 Method mā Yoshida, Kenta, Takano, Junichi, Ishizu, Yuri, Lezhava, Alexander, Ieiri, Ichiro, Maeda, Kazuya, Hayashizaki, Yoshihide, Sugiyama, Yuichi

    I whakaputaina 2013
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  16. 16
    Comprehensive PBPK Model of Rifampicin for Quantitative Prediction of Complex Drug‐Drug Interactions: CYP3A/2C9 Induction and OATP Inhibition Effects

    Comprehensive PBPK Model of Rifampicin for Quantitative Prediction of Complex Drug‐Drug Interactions: CYP3A/2C9 Induction and OATP Inhibition Effects mā Asaumi, Ryuta, Toshimoto, Kota, Tobe, Yoshifusa, Hashizume, Kenta, Nunoya, Ken‐ichi, Imawaka, Haruo, Lee, Wooin, Sugiyama, Yuichi

    I whakaputaina 2018
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  17. 17
    PBPK Modeling of Coproporphyrin I as an Endogenous Biomarker for Drug Interactions Involving Inhibition of Hepatic OATP1B1 and OATP1B3

    PBPK Modeling of Coproporphyrin I as an Endogenous Biomarker for Drug Interactions Involving Inhibition of Hepatic OATP1B1 and OATP1B3 mā Yoshikado, Takashi, Toshimoto, Kota, Maeda, Kazuya, Kusuhara, Hiroyuki, Kimoto, Emi, Rodrigues, A. David, Chiba, Koji, Sugiyama, Yuichi

    I whakaputaina 2018
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  18. 18
    In vivo Cisplatin Resistance Depending upon Canalicular Multispecific Organic Anion Transporter (cMOAT)

    In vivo Cisplatin Resistance Depending upon Canalicular Multispecific Organic Anion Transporter (cMOAT) mā Minamino, Tomoyoshi, Tamai, Mitsuo, Itoh, Yoshie, Tatsumi, Yasuaki, Nomura, Masaaki, Yokogawa, Koichi, Suzuki, Hiroshi, Sugiyama, Yuichi, Ohshima, Tohru, Miyamoto, Ken‐ichi

    I whakaputaina 1999
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  19. 19
    Posttranslational negative regulation of glycosylated and non-glycosylated BCRP expression by Derlin-1

    Posttranslational negative regulation of glycosylated and non-glycosylated BCRP expression by Derlin-1 mā Sugiyama, Takashi, Shuto, Tsuyoshi, Suzuki, Shingo, Sato, Takashi, Koga, Tomoaki, Suico, Mary Ann, Kusuhara, Hiroyuki, Sugiyama, Yuichi, Cyr, Douglas M., Kai, Hirofumi

    I whakaputaina 2010
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  20. 20
    Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective from the International Transporter Consortium

    Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective from the International Transporter Consortium mā Yee, Sook Wah, Brackman, Deanna J, Ennis, Elizabeth A., Sugiyama, Yuichi, Kamdem, Landry K., Blanchard, Rebecca, Galetin, Aleksandra, Zhang, Lei, Giacomini, Kathleen M.

    I whakaputaina 2018
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