Rezultati - Stringham, Heather M

Meta-Analysis of Gene-Environment Interaction Exploiting Gene-Environment Independence Across Multiple Case-Control Studies od Estes, Jason P., Rice, John D., Li, Shi, Stringham, Heather M., Boehnke, Michael, Mukherjee, Bhramar

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Subset-Based Analysis using Gene-Environment Interactions for Discovery of Genetic Associations across Multiple Studies or Phenotypes od Yu, Youfei, Xia, Lu, Lee, Seunggeun, Zhou, Xiang, Stringham, Heather M, Boehnke, Michael, Mukherjee, Bhramar

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The role of covariate heterogeneity in meta-analysis of gene-environment interactions with quantitative traits od Li, Shi, Mukherjee, Bhramar, Taylor, Jeremy M.G., Rice, Kenneth M., XiaoquanWen, Rice, John D., Stringham, Heather M., Boehnke, Michael

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Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns od Kim, Daniel Seung, Jackson, Anne U., Li, Yatong K., Stringham, Heather M., Kuusisto, Johanna, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Burant, Charles F., Salomaa, Veikko, Boehnke, Michael, Laakso, Markku, Speliotes, Elizabeth K.

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Additive Effects of Genetic Variation in GCK and G6PC2 on Insulin Secretion and Fasting Glucose od Li, Xia, Shu, Yu-Hsiang, Xiang, Anny H., Trigo, Enrique, Kuusisto, Johanna, Hartiala, Jaana, Swift, Amy J., Kawakubo, Miwa, Stringham, Heather M., Bonnycastle, Lori L., Lawrence, Jean M., Laakso, Markku, Allayee, Hooman, Buchanan, Thomas A., Watanabe, Richard M.

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Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study od Davis, James P., Huyghe, Jeroen R., Locke, Adam E., Jackson, Anne U., Sim, Xueling, Stringham, Heather M., Teslovich, Tanya M., Welch, Ryan P., Fuchsberger, Christian, Narisu, Narisu, Chines, Peter S., Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Kuusisto, Johanna, Collins, Francis S., Laakso, Markku, Boehnke, Michael, Mohlke, Karen L.

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Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution od Wu, Ying, Broadaway, K Alaine, Raulerson, Chelsea K, Scott, Laura J, Pan, Calvin, Ko, Arthur, He, Aiqing, Tilford, Charles, Fuchsberger, Christian, Locke, Adam E, Stringham, Heather M, Jackson, Anne U, Narisu, Narisu, Kuusisto, Johanna, Pajukanta, Päivi, Collins, Francis S, Boehnke, Michael, Laakso, Markku, Lusis, Aldons J, Civelek, Mete, Mohlke, Karen L

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Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits od Civelek, Mete, Wu, Ying, Pan, Calvin, Raulerson, Chelsea K., Ko, Arthur, He, Aiqing, Tilford, Charles, Saleem, Niyas K., Stančáková, Alena, Scott, Laura J., Fuchsberger, Christian, Stringham, Heather M., Jackson, Anne U., Narisu, Narisu, Chines, Peter S., Small, Kerrin S., Kuusisto, Johanna, Parks, Brian W., Pajukanta, Päivi, Kirchgessner, Todd, Collins, Francis S., Gargalovic, Peter S., Boehnke, Michael, Laakso, Markku, Mohlke, Karen L., Lusis, Aldons J.

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ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition od El-Sayed Moustafa, Julia S., Jackson, Anne U., Brotman, Sarah M., Guan, Li, Villicaña, Sergio, Roberts, Amy L., Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R., Narisu, Narisu, Stringham, Heather M., Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Collins, Francis S., Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A., Laakso, Markku, Falchi, Mario, Bell, Jordana T., Scott, Laura J., Mohlke, Karen L., Small, Kerrin S.

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Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits od Raulerson, Chelsea K., Ko, Arthur, Kidd, John C., Currin, Kevin W., Brotman, Sarah M., Cannon, Maren E., Wu, Ying, Spracklen, Cassandra N., Jackson, Anne U., Stringham, Heather M., Welch, Ryan P., Fuchsberger, Christian, Locke, Adam E., Narisu, Narisu, Lusis, Aldons J., Civelek, Mete, Furey, Terrence S., Kuusisto, Johanna, Collins, Francis S., Boehnke, Michael, Scott, Laura J., Lin, Dan-Yu, Love, Michael I., Laakso, Markku, Pajukanta, Päivi, Mohlke, Karen L.

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Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences od Spracklen, Cassandra N., Iyengar, Apoorva K., Vadlamudi, Swarooparani, Raulerson, Chelsea K., Jackson, Anne U., Brotman, Sarah M., Wu, Ying, Cannon, Maren E., Davis, James P., Crain, Aaron T., Currin, Kevin W., Perrin, Hannah J., Narisu, Narisu, Stringham, Heather M., Fuchsberger, Christian, Locke, Adam E., Welch, Ryan P., Kuusisto, Johanna K., Pajukanta, Päivi, Scott, Laura J., Li, Yun, Collins, Francis S., Boehnke, Michael, Laakso, Markku, Mohlke, Karen L.

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Exome array analysis identifies novel loci and low-frequency variants for insulin processing and secretion od Huyghe, Jeroen R, Jackson, Anne U, Fogarty, Marie P, Buchkovich, Martin L, Stančáková, Alena, Stringham, Heather M, Sim, Xueling, Yang, Lingyao, Fuchsberger, Christian, Cederberg, Henna, Chines, Peter S, Teslovich, Tanya M, Romm, Jane M, Ling, Hua, McMullen, Ivy, Ingersoll, Roxann, Pugh, Elizabeth W, Doheny, Kimberly F, Neale, Benjamin M, Daly, Mark J, Kuusisto, Johanna, Scott, Laura J, Kang, Hyun Min, Collins, Francis S, Abecasis, Gonçalo R, Watanabe, Richard M, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L

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Joint Analysis of Individual Participants’ Data from 17 Studies on the Association of the IL6 Variant -174G>C with Circulating Glucose Levels, Interleukin-6 Levels, and Body-Mass I... od Huth, Cornelia, Illig, Thomas, Herder, Christian, Gieger, Christian, Grallert, Harald, Vollmert, Caren, Rathmann, Wolfgang, Hamid, Yasmin H., Pedersen, Oluf, Hansen, Torben, Thorand, Barbara, Meisinger, Christa, Döring, Angela, Klopp, Norman, Gohlke, Henning, Lieb, Wolfgang, Hengstenberg, Christian, Lyssenko, Valeriya, Groop, Leif, Ireland, Helen, Stephens, Jeffrey W., Asterholm, Ingrid Wernstedt, Jansson, John-Olov, Boeing, Heiner, Möhlig, Matthias, Stringham, Heather M., Boehnke, Michael, Tuomilehto, Jaakko, Fernandez-Real, Jose-Manuel, Lopez-Bermejo, Abel, Gallart, Luis, Vendrell, Joan, Humphries, Steve E., Kronenberg, Florian, Wichmann, H.-Erich, Heid, Iris M.

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Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci od Service, Susan K., Teslovich, Tanya M., Fuchsberger, Christian, Ramensky, Vasily, Yajnik, Pranav, Koboldt, Daniel C., Larson, David E., Zhang, Qunyuan, Lin, Ling, Welch, Ryan, Ding, Li, McLellan, Michael D., O'Laughlin, Michele, Fronick, Catrina, Fulton, Lucinda L., Magrini, Vincent, Swift, Amy, Elliott, Paul, Jarvelin, Marjo-Riitta, Kaakinen, Marika, McCarthy, Mark I., Peltonen, Leena, Pouta, Anneli, Bonnycastle, Lori L., Collins, Francis S., Narisu, Narisu, Stringham, Heather M., Tuomilehto, Jaakko, Ripatti, Samuli, Fulton, Robert S., Sabatti, Chiara, Wilson, Richard K., Boehnke, Michael, Freimer, Nelson B.

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Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes od Jaiswal, Siddhartha, Fontanillas, Pierre, Flannick, Jason, Manning, Alisa, Grauman, Peter V., Mar, Brenton G., Lindsley, R. Coleman, Mermel, Craig H., Burtt, Noel, Chavez, Alejandro, Higgins, John M., Moltchanov, Vladislav, Kuo, Frank C., Kluk, Michael J., Henderson, Brian, Kinnunen, Leena, Koistinen, Heikki A., Ladenvall, Claes, Getz, Gad, Correa, Adolfo, Banahan, Benjamin F., Gabriel, Stacey, Kathiresan, Sekar, Stringham, Heather M., McCarthy, Mark I., Boehnke, Michael, Tuomilehto, Jaakko, Haiman, Christopher, Groop, Leif, Atzmon, Gil, Wilson, James G., Neuberg, Donna, Altshuler, David, Ebert, Benjamin L.

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The genetic regulatory signature of type 2 diabetes in human skeletal muscle od Scott, Laura J., Erdos, Michael R., Huyghe, Jeroen R., Welch, Ryan P., Beck, Andrew T., Wolford, Brooke N., Chines, Peter S., Didion, John P., Narisu, Narisu, Stringham, Heather M., Taylor, D. Leland, Jackson, Anne U., Vadlamudi, Swarooparani, Bonnycastle, Lori L., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Albanus, Ricardo D'Oliveira, Kiseleva, Anna, Hensley, John, Crawford, Gregory E., Jiang, Hui, Wen, Xiaoquan, Watanabe, Richard M., Lakka, Timo A., Mohlke, Karen L., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J.

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Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study od Teslovich, Tanya M, Kim, Daniel Seung, Yin, Xianyong, Stančáková, Alena, Jackson, Anne U, Wielscher, Matthias, Naj, Adam, Perry, John R B, Huyghe, Jeroen R, Stringham, Heather M, Davis, James P, Raulerson, Chelsea K, Welch, Ryan P, Fuchsberger, Christian, Locke, Adam E, Sim, Xueling, Chines, Peter S, Narisu, Narisu, Kangas, Antti J, Soininen, Pasi, Ala-Korpela, Mika, Gudnason, Vilmundur, Musani, Solomon K, Jarvelin, Marjo-Riitta, Schellenberg, Gerard D, Speliotes, Elizabeth K, Kuusisto, Johanna, Collins, Francis S, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L

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ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition—implications for COVID-19 od El-Sayed Moustafa, Julia S., Jackson, Anne U., Brotman, Sarah M., Guan, Li, Villicaña, Sergio, Roberts, Amy L., Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R., Narisu, Narisu, Stringham, Heather M., Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Acors, Sam, Kouphou, Neophytos, Wadge, Samuel, Duncan, Emma L., Steves, Claire J., Doores, Katie J., Malim, Michael H., Collins, Francis S., Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A., Laakso, Markku, Falchi, Mario, Bell, Jordana T., Scott, Laura J., Mohlke, Karen L., Small, Kerrin S.

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Common variants in the GDF5-BFZB region are associated with variation in human height od Sanna, Serena, Jackson, Anne U., Nagaraja, Ramaiah, Willer, Cristen J., Chen, Wei-Min, Bonnycastle, Lori L., Shen, Haiqing, Timpson, Nicholas, Lettre, Guillaume, Usala, Gianluca, Chines, Peter S., Stringham, Heather M., Dei, Mariano, Lai, Sandra, Albai, Giuseppe, Crisponi, Laura, Naitza, Silvia, Doheny, Kimberly F., Pugh, Elizabeth W., Ben-Shlomo, Yoav, Ebrahim, Shah, Lawlor, Debbie A., Bergman, Richard N., Watanabe, Richard M., Uda, Manuela, Tuomilehto, Jaakko, Coresh, Josef, Hirschhorn, Joel N., Shuldiner, Alan R., Schlessinger, David, Collins, Francis S., Smith, George Davey, Boerwinkle, Eric, Cao, Antonio, Boehnke, Michael, Abecasis, Gonçalo R., Mohlke, Karen L.

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Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci od Yin, Xianyong, Chan, Lap Sum, Bose, Debraj, Jackson, Anne U., VandeHaar, Peter, Locke, Adam E., Fuchsberger, Christian, Stringham, Heather M., Welch, Ryan, Yu, Ketian, Fernandes Silva, Lilian, Service, Susan K., Zhang, Daiwei, Hector, Emily C., Young, Erica, Ganel, Liron, Das, Indraniel, Abel, Haley, Erdos, Michael R., Bonnycastle, Lori L., Kuusisto, Johanna, Stitziel, Nathan O., Hall, Ira M., Wagner, Gregory R., Kang, Jian, Morrison, Jean, Burant, Charles F., Collins, Francis S., Ripatti, Samuli, Palotie, Aarno, Freimer, Nelson B., Mohlke, Karen L., Scott, Laura J., Wen, Xiaoquan, Fauman, Eric B., Laakso, Markku, Boehnke, Michael

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