Search Results - Steven W. Paugh

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  1. 1
    “Inside-Out” Signaling of Sphingosine-1-Phosphate: Therapeutic Targets

    “Inside-Out” Signaling of Sphingosine-1-Phosphate: Therapeutic Targets by Kazuaki Takabe, Steven W. Paugh, Sheldon Milstien, Sarah Spiegel

    Published 2008
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  2. 2
    Involvement of Sphingosine Kinase 2 in p53-Independent Induction of p21 by the Chemotherapeutic Drug Doxorubicin

    Involvement of Sphingosine Kinase 2 in p53-Independent Induction of p21 by the Chemotherapeutic Drug Doxorubicin by Heidi Sankala, Nitai C. Hait, Steven W. Paugh, Dai Shida, Sandrine Lépine, Lynne W. Elmore, Paul Dent, Sheldon Milstien, Sarah Spiegel

    Published 2007
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  3. 3
    Apoptosis induces expression of sphingosine kinase 1 to release sphingosine‐1‐phosphate as a “come‐and‐get‐me” signal

    Apoptosis induces expression of sphingosine kinase 1 to release sphingosine‐1‐phosphate as a “come‐and‐get‐me” signal by David Gude, Sergio E. Alvarez, Steven W. Paugh, Poulami Mitra, JiaDe Yu, Rachael Griffiths, Suzanne E. Barbour, Sheldon Milstien, Sarah Spiegel

    Published 2008
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  4. 4
    EGF regulates plasminogen activator inhibitor‐1 (PAI‐1) by a pathway involving c‐Src, PKCδ, and sphingosine kinase 1 in glioblastoma cells

    EGF regulates plasminogen activator inhibitor‐1 (PAI‐1) by a pathway involving c‐Src, PKCδ, and sphingosine kinase 1 in glioblastoma cells by Barbara S. Paugh, Steven W. Paugh, Lauren Bryan, Dmitri Kapitonov, Katarzyna M. Wilczynska, Sunita M. Gopalan, Hanna Rokita, Sheldon Milstien, Sarah Spiegel, Tomasz Kordula

    Published 2007
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  5. 5
    A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia

    A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia by Steven W. Paugh, Barbara S. Paugh, Mohamed Rahmani, Dmitri Kapitonov, Jorge A. Almenara, Tomasz Kordula, Sheldon Milstien, Jeffrey K. Adams, Robert E. Zipkin, Steven Grant, Sarah Spiegel

    Published 2008
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  6. 6
    The SWI/SNF Chromatin-Remodeling Complex and Glucocorticoid Resistance in Acute Lymphoblastic Leukemia

    The SWI/SNF Chromatin-Remodeling Complex and Glucocorticoid Resistance in Acute Lymphoblastic Leukemia by Nicolas Pottier, Wenjian Yang, Mahfoud Assem, John C. Panetta, Deqing Pei, Steven W. Paugh, Cheng Cheng, Monique L. den Boer, Mary V. Relling, Rob Pieters, William E. Evans, Meyling Cheok

    Published 2008
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  7. 7
    Interleukin-1 Regulates the Expression of Sphingosine Kinase 1 in Glioblastoma Cells

    Interleukin-1 Regulates the Expression of Sphingosine Kinase 1 in Glioblastoma Cells by Barbara S. Paugh, Lauren Bryan, Steven W. Paugh, Katarzyna M. Wilczynska, Silvina Mónica Álvarez, Sandeep K. Singh, Dmitri Kapitonov, Hanna Rokita, Sarah Wright, Irene Griswold‐Prenner, Sheldon Milstien, Sarah Spiegel, Tomasz Kordula

    Published 2008
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  8. 8
    Loss of TBL1XR1 Disrupts Glucocorticoid Receptor Recruitment to Chromatin and Results in Glucocorticoid Resistance in a B-Lymphoblastic Leukemia Model

    Loss of TBL1XR1 Disrupts Glucocorticoid Receptor Recruitment to Chromatin and Results in Glucocorticoid Resistance in a B-Lymphoblastic Leukemia Model by Courtney L. Jones, Teena Bhatla, Roy Blum, Jinhua Wang, Steven W. Paugh, Xin Wen, Wallace Bourgeois, Danielle S. Bitterman, Elizabeth A. Raetz, D. Morrison, David T. Teachey, William E. Evans, Michael J. Garabedian, William L. Carroll

    Published 2014
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  9. 9
    PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity

    PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity by Gabriele Stocco, Wenjian Yang, Kristine R. Crews, William E. Thierfelder, Giuliana Decorti, Margherita Londero, Raffaella Franca, Marco Rabusin, Maria Grazia Valsecchi, Deqing Pei, Cheng Cheng, Steven W. Paugh, Laura B. Ramsey, B Diouf, J. Robert McCorkle, Terreia S. Jones, Ching-Hon Pui, Mary V. Relling, William E. Evans

    Published 2012
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  10. 10
    MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression

    MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression by Steven W. Paugh, David Raymond Coss, Ju Bao, Lucas Laudermilk, Christy R. Grace, Antonio M. Ferreira, M. Brett Waddell, Granger Ridout, Deanna Naeve, Michael R. Leuze, Philip LoCascio, John C. Panetta, Mark R. Wilkinson, Ching‐Hon Pui, Clayton W. Naeve, Edward C. Uberbacher, Erik Bonten, William E. Evans

    Published 2016
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  11. 11
    Association of an Inherited Genetic Variant With Vincristine-Related Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia

    Association of an Inherited Genetic Variant With Vincristine-Related Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia by B Diouf, Kristine R. Crews, Glen Lew, Deqing Pei, Cheng Cheng, Ju Bao, Jie Zheng, Wenjian Yang, Yiping Fan, Heather E. Wheeler, Claudia Wing, Shannon M. Delaney, Masaaki Komatsu, Steven W. Paugh, J. Robert McCorkle, Xiaomin Lu, Naomi J. Winick, William L. Carroll, Mignon L. Loh, Stephen P. Hunger, Meenakshi Devidas, Ching‐Hon Pui, M. Eileen Dolan, Mary V. Relling, William E. Evans

    Published 2015
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  12. 12
    Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia

    Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia by Robert J. Autry, Steven W. Paugh, Robert Carter, Lei Shi, Jingjing Liu, Daniel C. Ferguson, Calvin E. Lau, Erik Bonten, Wenjian Yang, J. Robert McCorkle, Jordan A. Beard, John C. Panetta, Jonathan D. Diedrich, Kristine R. Crews, Deqing Pei, Christopher J. Coke, Sivaraman Natarajan, Alireza Khatamian, Seth E. Karol, Elixabet López-López, B Diouf, Colton Smith, Yoshihiro Gocho, Kohei Hagiwara, Kathryn G. Roberts, Stanley Pounds, Steven M. Kornblau, Wendy Stock, Elisabeth Paietta, Mark R. Litzow, Hiroto Inaba, Charles G. Mullighan, Sima Jeha, Ching‐Hon Pui, Cheng Cheng, Daniel Savic, Jiyang Yu, Charles Gawad, Mary V. Relling, Jun J. Yang, William E. Evans

    Published 2020
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  13. 13
    NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells

    NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells by Steven W. Paugh, Erik Bonten, Daniel Savic, Laura B. Ramsey, William E. Thierfelder, Prajwal Gurung, R. K. Subbarao Malireddi, Marcelo Actis, Anand Mayasundari, Jaeki Min, David Raymond Coss, Lucas Laudermilk, John C. Panetta, J. Robert McCorkle, Yiping Fan, Kristine R. Crews, Gabriele Stocco, Mark R. Wilkinson, Antonio M. Ferreira, Cheng Cheng, Wenjian Yang, Seth E. Karol, Christian A. Fernandez, B Diouf, Colton Smith, J. Kevin Hicks, Alessandra Zanut, Audrey Giordanengo, Daniel J. Crona, Joy J. Bianchi, Linda Holmfeldt, Charles G. Mullighan, Monique L. den Boer, Rob Pieters, Sima Jeha, Thomas L. Dunwell, Farida Latif, Deepa Bhojwani, William L. Carroll, Ching‐Hon Pui, R Myers, R. Kiplin Guy, Thirumala‐Devi Kanneganti, Mary V. Relling, William E. Evans

    Published 2015
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  14. 14
    Novel mutations target distinct subgroups of medulloblastoma

    Novel mutations target distinct subgroups of medulloblastoma by Giles Robinson, Matthew Parker, Tanya A. Kranenburg, Charles Lu, Xiang Chen, Li Ding, Timothy N. Phoenix, Erin Hedlund, Lei Wei, Xiaoyan Zhu, Nader Chalhoub, Suzanne J. Baker, Robert Huether, Richard W. Kriwacki, Natasha Curley, Radhika Thiruvenkatam, Jianmin Wang, Gang Wu, Michael Rusch, Xin Hong, Jared Becksfort, Pankaj Gupta, Jing Ma, John Easton, Bhavin Vadodaria, Arzu Onar‐Thomas, Tong Lin, Shaoyi Li, Stanley Pounds, Steven W. Paugh, David Zhao, Daisuke Kawauchi, Martine F. Roussel, David Finkelstein, David W. Ellison, Ching C. Lau, Éric Bouffet, Tim Hassall, Sridharan Gururangan, Richard J. Cohn, Robert S. Fulton, Lucinda Fulton, David J. Dooling, Kerri Ochoa, Amar Gajjar, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Jinghui Zhang, Richard J. Gilbertson

    Published 2012
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  15. 15
    Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia

    Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia by Kathryn G. Roberts, Ryan D. Morin, Jinghui Zhang, Martin Hirst, Yongjun Zhao, Xiaoping Su, Shann-Ching Chen, Debbie Payne-Turner, Michelle L. Churchman, Richard C. Harvey, Xiang Chen, Corynn Kasap, Chunhua Yan, Jared Becksfort, Richard P. Finney, David T. Teachey, Shannon L. Maude, Kane Tse, Richard A. Moore, Steven J.M. Jones, Karen Mungall, İnanç Birol, Michael N. Edmonson, Ying Hu, Kenneth Buetow, I‐Ming Chen, William L. Carroll, Lei Wei, Jing Ma, Maria Kleppe, Ross L. Levine, Guillermo Garcia‐Manero, Eric Larsen, Neil P. Shah, Meenakshi Devidas, Gregory H. Reaman, Malcolm A. Smith, Steven W. Paugh, William E. Evans, Stephan A. Grupp, Sima Jeha, Ching‐Hon Pui, Daniela S. Gerhard, J R Downing, Cheryl L. Willman, Mignon L. Loh, Stephen P. Hunger, Marco A. Marra, Charles G. Mullighan

    Published 2012
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  16. 16
    Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

    Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia by Kathryn G. Roberts, Yongjin Li, Debbie Payne-Turner, Richard C. Harvey, Yung‐Li Yang, Deqing Pei, Kelly McCastlain, Li Ding, Charles Lu, Guangchun Song, Jing Ma, Jared Becksfort, Michael Rusch, Shann-Ching Chen, John Easton, Jinjun Cheng, Kristy Boggs, Natalia Santiago-Morales, Ilaria Iacobucci, Robert S. Fulton, Ji Wen, Marcus Valentine, Cheng Cheng, Steven W. Paugh, Meenakshi Devidas, I‐Ming Chen, Shalini C. Reshmi, Amy Smith, Erin Hedlund, Pankaj Gupta, Panduka Nagahawatte, Gang Wu, Xiang Chen, Donald Yergeau, Bhavin Vadodaria, Heather L. Mulder, Naomi J. Winick, Eric Larsen, William L. Carroll, Nyla A. Heerema, Andrew J. Carroll, Guy H. Grayson, Sarah K. Tasian, Andrew S. Moore, Frank Keller, Melissa Frei‐Jones, James A. Whitlock, Elizabeth A. Raetz, Deborah L. White, Timothy P. Hughes, Jaime M. Guidry Auvil, Malcolm A. Smith, Guido Marcucci, Clara D. Bloomfield, Krzysztof Mrózek, Jessica Kohlschmidt, Wendy Stock, Steven M. Kornblau, Marina Konopleva, Elisabeth Paietta, Ching‐Hon Pui, Sima Jeha, Mary V. Relling, William E. Evans, Daniela S. Gerhard, Julie M. Gastier-Foster, Elaine R. Mardis, Richard K. Wilson, Mignon L. Loh, James R. Downing, Stephen P. Hunger, Cheryl L. Willman, Jinghui Zhang, Charles G. Mullighan

    Published 2014
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