Search Results - Steven M. Offer

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  1. 1
    Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

    Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy by Shikshya Shrestha, Steven M. Offer

    Published 2016
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  2. 2
    Testing for Dihydropyrimidine Dehydrogenase Deficiency to Individualize 5-Fluorouracil Therapy

    Testing for Dihydropyrimidine Dehydrogenase Deficiency to Individualize 5-Fluorouracil Therapy by Robert B. Diasio, Steven M. Offer

    Published 2022
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  3. 3
    Phenotypic Profiling of <i>DPYD</i> Variations Relevant to 5-Fluorouracil Sensitivity Using Real-time Cellular Analysis and <i>In Vitro</i> Measurement of Enzyme Activity

    Phenotypic Profiling of <i>DPYD</i> Variations Relevant to 5-Fluorouracil Sensitivity Using Real-time Cellular Analysis and <i>In Vitro</i> Measurement of Enzyme Activity by Steven M. Offer, Natalie J. Wegner, Croix C. Fossum, Kangsheng Wang, Robert B. Diasio

    Published 2013
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  4. 4
    Polymorphisms in<i>MIR27A</i>Associated with Early-Onset Toxicity in Fluoropyrimidine-Based Chemotherapy

    Polymorphisms in<i>MIR27A</i>Associated with Early-Onset Toxicity in Fluoropyrimidine-Based Chemotherapy by Ursula Amstutz, Steven M. Offer, Johanna Sistonen, Markus Joerger, Robert B. Diasio, Carlo R. Largiadèr

    Published 2015
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  5. 5
    A DPYD Variant (Y186C) in Individuals of African Ancestry Is Associated With Reduced DPD Enzyme Activity

    A DPYD Variant (Y186C) in Individuals of African Ancestry Is Associated With Reduced DPD Enzyme Activity by Steven M. Offer, A M Lee, Lori K. Mattison, Caroline Fossum, Natalie J. Wegner, Robert B. Diasio

    Published 2013
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  6. 6
    Gene‐Specific Variant Classifier (DPYD‐Varifier) to Identify Deleterious Alleles of Dihydropyrimidine Dehydrogenase

    Gene‐Specific Variant Classifier (DPYD‐Varifier) to Identify Deleterious Alleles of Dihydropyrimidine Dehydrogenase by Shikshya Shrestha, Cheng Zhang, Calvin R. Jerde, Qian Nie, Hu Li, Steven M. Offer, Robert B. Diasio

    Published 2018
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  7. 7
    Comparative Functional Analysis of <i>DPYD</i> Variants of Potential Clinical Relevance to Dihydropyrimidine Dehydrogenase Activity

    Comparative Functional Analysis of <i>DPYD</i> Variants of Potential Clinical Relevance to Dihydropyrimidine Dehydrogenase Activity by Steven M. Offer, Croix C. Fossum, Natalie J. Wegner, Alexander J. Stuflesser, Gabriel L. Butterfield, Robert B. Diasio

    Published 2014
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  8. 8
    microRNAs miR-27a and miR-27b Directly Regulate Liver Dihydropyrimidine Dehydrogenase Expression through Two Conserved Binding Sites

    microRNAs miR-27a and miR-27b Directly Regulate Liver Dihydropyrimidine Dehydrogenase Expression through Two Conserved Binding Sites by Steven M. Offer, Gabriel L. Butterfield, Calvin R. Jerde, Croix C. Fossum, Natalie J. Wegner, Robert B. Diasio

    Published 2014
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  9. 9
    Updated <i>DPYD</i><scp>HapB3</scp> haplotype structure and implications for pharmacogenomic testing

    Updated <i>DPYD</i><scp>HapB3</scp> haplotype structure and implications for pharmacogenomic testing by Amy Turner, Cyrine E. Haidar, Wenjian Yang, Erin C. Boone, Steven M. Offer, Philip E. Empey, Andrew Haddad, Saba Tahir, Gunter Scharer, Ulrich Broeckel, Andrea Gaedigk

    Published 2023
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  10. 10
    Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency

    Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency by Qiang Pan‐Hammarström, Ulrich Salzer, Likun Du, Janne Björkander, Charlotte Cunningham‐Rundles, David L. Nelson, Chiara Bacchelli, H. Bobby Gaspar, Steven M. Offer, Timothy W. Behrens, Bodo Grimbacher, Lennart Hammarström

    Published 2007
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  11. 11
    Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update

    Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update by Ursula Amstutz, Linda M. Henricks, Steven M. Offer, Julia M. Barbarino, Jan H.M. Schellens, Jesse J. Swen, Teri E. Klein, Howard L. McLeod, Kelly E. Caudle, Robert B. Diasio, Matthias Schwab

    Published 2017
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  12. 12
    Symmetric inheritance of parental histones contributes to safeguarding the fate of mouse embryonic stem cells during differentiation

    Symmetric inheritance of parental histones contributes to safeguarding the fate of mouse embryonic stem cells during differentiation by Qing Wen, Jiaqi Zhou, Congcong Tian, Xinran Li, Guibing Song, Yuan Gao, Yaping Sun, Chiyuan Ma, Sitong Yao, Xiaoyan Liang, Xing Kang, Nan Wang, Yuan Yao, Hongbao Wang, Xiao‐Huan Liang, Jialin Tang, Steven M. Offer, Xiaohua Lei, Chuanhe Yu, Xiangyu Liu, Zichuan Liu, Zhiquan Wang, Haiyun Gan

    Published 2023
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  13. 13
    A phosphotyrosine switch regulates organic cation transporters

    A phosphotyrosine switch regulates organic cation transporters by Jason A. Sprowl, Su Sien Ong, Alice A. Gibson, Shuiying Hu, Guoqing Du, Wenwei Lin, Lie Li, Shashank Bharill, Rachel A. Ness, Adrian Stecuła, Steven M. Offer, Robert B. Diasio, Anne T. Nies, Matthias Schwab, Guido Cavaletti, Eberhard Schlatter, Giuliano Ciarimboli, Jan H.M. Schellens, Ehud Y. Isacoff, Andrej Šali, Taosheng Chen, Sharyn D. Baker, Alex Sparreboom, Navjotsingh Pabla

    Published 2016
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  14. 14
    Role for Msh5 in the regulation of Ig class switch recombination

    Role for Msh5 in the regulation of Ig class switch recombination by Hideharu Sekine, Ricardo C. Ferreira, Qiang Pan‐Hammarström, Robert Graham, Beth Ziemba, Sandra S. de Vries, Jiabin Liu, Keli L. Hippen, Thearith Koeuth, Ward Ortmann, Akiko Iwahori, Margaret K. Elliott, Steven M. Offer, Cara Skon-Hegg, Likun Du, Jill Novitzke, Annette T. Lee, Nianxi Zhao, Joshua D. Tompkins, David Altshuler, Peter K. Gregersen, Charlotte Cunningham‐Rundles, Reuben S. Harris, Chengtao Her, David L. Nelson, Lennart Hammarström, Gary S. Gilkeson, Timothy W. Behrens

    Published 2007
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