Search Results - Steven M. Corsello

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  1. 1
    Gefitinib induces myeloid differentiation of acute myeloid leukemia

    Gefitinib induces myeloid differentiation of acute myeloid leukemia by Kimberly Stegmaier, Steven M. Corsello, Kenneth N. Ross, Jenny Wong, Daniel J. DeAngelo, Todd R. Golub

    Published 2005
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  2. 2
    RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition

    RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition by Lishan Fang, Dane Ford-Roshon, Max Russo, Casey O’Brien, Xiaozhe Xiong, Carino Gurjao, Maximilien Grandclaudon, Srivatsan Raghavan, Steven M. Corsello, Steven A. Carr, Namrata D. Udeshi, James Berstler, Ewa Sicińska, Kimmie Ng, Marios Giannakis

    Published 2022
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  3. 3
    The Drug Repurposing Hub: a next-generation drug library and information resource

    The Drug Repurposing Hub: a next-generation drug library and information resource by Steven M. Corsello, Joshua A. Bittker, Zihan Liu, Joshua Gould, Patrick McCarren, Jodi Hirschman, Stephen Johnston, Anita Vrcic, Bang Wong, Mariya Khan, Jacob K. Asiedu, Rajiv Narayan, Christopher C. Mader, Aravind Subramanian, Todd R. Golub

    Published 2017
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  4. 4
    Copper induces cell death by targeting lipoylated TCA cycle proteins

    Copper induces cell death by targeting lipoylated TCA cycle proteins by Peter Tsvetkov, Shannon Coy, Boryana Petrova, Margaret Dreishpoon, Ana Verma, Mai Abdusamad, Jordan Rossen, Lena Joesch-Cohen, Ranad Humeidi, Ryan D. Spangler, John K. Eaton, Evgeni M. Frenkel, Mustafa Kocak, Steven M. Corsello, Svetlana Lutsenko, Naama Kanarek, Sandro Santagata, Todd R. Golub

    Published 2022
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  5. 5
    A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer

    A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer by Frederick H. Wilson, Cory M. Johannessen, Federica Piccioni, Pablo Tamayo, Jong Wook Kim, Eliezer M. Van Allen, Steven M. Corsello, Marzia Capelletti, Antonio Calles, Mohit Butaney, Tanaz Sharifnia, Stacey B. Gabriel, Jill P. Mesirov, William C. Hahn, Jeffrey A. Engelman, Matthew Meyerson, David E. Root, Pasi A. Jänne, Levi A. Garraway

    Published 2015
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  6. 6
    Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors

    Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors by Wenchao Lu, Mengyang Fan, Wenzhi Ji, Jason Tse, Inchul You, Scott B. Ficarro, Isidoro Tavares, Jianwei Che, Audrey Y. Kim, Xijun Zhu, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Stephen M. Hinshaw, Behnam Nabet, Steven M. Corsello, Nicholas Kwiatkowski, Jarrod A. Marto, Tinghu Zhang, Nathanael S. Gray

    Published 2023
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  7. 7
    Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

    Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer by Carino Gurjao, David Liu, Matan Hofree, Saud H. AlDubayan, Isaac Wakiro, Mei-Ju Su, Kristen D. Felt, Evisa Gjini, Lauren K. Brais, Asaf Rotem, Michael H. Rosenthal, Orit Rozenblatt–Rosen, Scott J. Rodig, Kimmie Ng, Eliezer M. Van Allen, Steven M. Corsello, Shuji Ogino, Aviv Regev, Jonathan A. Nowak, Marios Giannakis

    Published 2019
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  8. 8
    The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

    The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K by Mikołaj Słabicki, Zuzanna Kozicka, Georg Petzold, Yen-Der Li, Manisha Manojkumar, R.D. Bunker, Katherine A. Donovan, Quinlan Sievers, Jonas Koeppel, Dakota J. Suchyta, Adam S. Sperling, Emma C. Fink, Jessica A. Gasser, Li R. Wang, Steven M. Corsello, Rob S. Sellar, Max Jan, Dennis Gillingham, Claudia Scholl, Stefan Fröhling, Todd R. Golub, Eric S. Fischer, Nicolas H. Thomä, Benjamin L. Ebert

    Published 2020
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  9. 9
    Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles

    Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles by Eejung Kim, Nina Ilić, Yashaswi Shrestha, Lihua Zou, Atanas Kamburov, Cong Zhu, Xiaoping Yang, Rakela Lubonja, Nancy Tran, Cindy M. Nguyen, Michael S. Lawrence, Federica Piccioni, Mukta Bagul, John G. Doench, Candace R. Chouinard, Xiaoyun Wu, Larson Hogstrom, Ted Natoli, Pablo Tamayo, Heiko Horn, Steven M. Corsello, Kasper Lage, David E. Root, Aravind Subramanian, Todd R. Golub, Gad Getz, Jesse S. Boehm, William C. Hahn

    Published 2016
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  10. 10
    Virtual screening for small-molecule pathway regulators by image-profile matching

    Virtual screening for small-molecule pathway regulators by image-profile matching by Mohammad Hossein Rohban, Ashley M. Fuller, Ceryl Tan, Jonathan T. Goldstein, Deepsing Syangtan, Amos Gutnick, Ann Devine, Madhura P. Nijsure, Megan Rigby, Joshua R. Sacher, Steven M. Corsello, Grace B. Peppler, Marta Bogaczynska, Andrew S. Boghossian, Gabrielle E. Ciotti, Allison T. Hands, Aroonroj Mekareeya, Minh Doan, Jennifer Gale, Rik Derynck, Thomas J. Turbyville, Joel D. Boerckel, Shantanu Singh, Laura L. Kiessling, Thomas L. Schwarz, Xaralabos Varelas, Florence F. Wagner, Ran Kafri, T.S. Karin Eisinger‐Mathason, Anne E. Carpenter

    Published 2022
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  11. 11
    Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

    Discovering the anticancer potential of non-oncology drugs by systematic viability profiling by Steven M. Corsello, Rohith T. Nagari, Ryan D. Spangler, Jordan Rossen, Mustafa Kocak, Jordan Bryan, Ranad Humeidi, D. D. Peck, Xiaoyun Wu, Andrew Tang, Vickie M. Wang, Samantha Bender, Evan Lemire, Rajiv Narayan, Philip Montgomery, Uri Ben‐David, Colin W. Garvie, Yejia Chen, Matthew G. Rees, Nicholas Lyons, James M. McFarland, Bang Wong, Li Wang, Nancy Dumont, Patrick J. O’Hearn, Eric Stefan, John G. Doench, Caitlin Harrington, Heidi Greulich, Matthew Meyerson, Francisca Vázquez, Aravind Subramanian, Jennifer A. Roth, Joshua A. Bittker, Jesse S. Boehm, Christopher C. Mader, Aviad Tsherniak, Todd R. Golub

    Published 2020
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  12. 12
    Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study

    Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study by Arezou A. Ghazani, Nelly Oliver, Joseph P. St. Pierre, Andrea Garofalo, Irene Rainville, Elaine Hiller, Daniel J. Treacy, Vanesa Rojas‐Rudilla, Sam Wood, Elizabeth F. Bair, Michael Parello, Franklin W. Huang, Marios Giannakis, Frederick H. Wilson, Elizabeth H. Stover, Steven M. Corsello, Tom Nguyen, Huma Q. Rana, Alanna J. Church, Carol Lowenstein, Carrie Cibulskis, Ali Amin‐Mansour, Jennifer Heng, Lauren K. Brais, Abigail Santos, Michael Bauer, Amanda Waldron, Peter Lo, Megan J. Gorman, Christine Lydon, Marisa W. Welch, Philip G. McNamara, Stacey Gabriel, Lynette M. Sholl, Neal I. Lindeman, Judy E. Garber, Steven Joffe, Eliezer M. Van Allen, Stacy W. Gray, Pasi A. Jänne, Levi A. Garraway, Nikhil Wagle

    Published 2017
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  13. 13
    A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles

    A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles by Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, D. D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie Donahue, Bina Julian, Mariya Khan, David Wadden, Ian C. P. Smith, Daniel D. Lam, Arthur Liberzon, Courtney Toder, Mukta Bagul, Marek Orzechowski, Oana M. Enache, Federica Piccioni, Alice H. Berger, Alykhan F. Shamji, Angela N. Brooks, Anita Vrcic, Corey Flynn, Jacqueline Rosains, David Y. Takeda, Desiree Davison, Justin Lamb, Kristin Ardlie, Larson Hogstrom, Nathanael S. Gray, Paul A. Clemons, Serena J. Silver, Xiaoyun Wu, Wen‐Ning Zhao, Willis Read-Button, Xiaohua Wu, Stephen J. Haggarty, Lucienne Ronco, Jesse S. Boehm, Stuart L. Schreiber, John G. Doench, Joshua A. Bittker, David E. Root, Bang Wong, Todd R. Golub

    Published 2017
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  14. 14
    A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles

    A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles by Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, D. D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie Donahue, Bina Julian, Mariya Khan, David Wadden, Ian C. P. Smith, Daniel D. Lam, Arthur Liberzon, Courtney Toder, Mukta Bagul, Marek Orzechowski, Oana M. Enache, Federica Piccioni, Sarah Johnson, Nicholas Lyons, Alice H. Berger, Alykhan F. Shamji, Angela N. Brooks, Anita Vrcic, Corey Flynn, Jacqueline Rosains, David Y. Takeda, Roger Hu, Desiree Davison, Justin Lamb, Kristin Ardlie, Larson Hogstrom, Peyton Greenside, Nathanael S. Gray, Paul A. Clemons, Serena J. Silver, Xiaoyun Wu, Wen‐Ning Zhao, Willis Read-Button, Xiaohua Wu, Stephen J. Haggarty, Lucienne Ronco, Jesse S. Boehm, Stuart L. Schreiber, John G. Doench, Joshua A. Bittker, David E. Root, Bang Wong, Todd R. Golub

    Published 2017
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