Resultats de la cerca - Steven Kregel

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  1. 1
    Critical Role of Serum Response Factor in Pulmonary Myofibroblast Differentiation Induced by TGF-β

    Critical Role of Serum Response Factor in Pulmonary Myofibroblast Differentiation Induced by TGF-β per Nathan Sandbo, Steven Kregel, Sébastien Taurin, Sangeeta Bhorade, Nickolai O. Dulin

    Publicat 2009
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  2. 2
    Control of Myofibroblast Differentiation by Microtubule Dynamics through a Regulated Localization of mDia2

    Control of Myofibroblast Differentiation by Microtubule Dynamics through a Regulated Localization of mDia2 per Nathan Sandbo, Caitlyn Ngam, Elizabeth Torr, Steven Kregel, Jacob Kach, Nickolai O. Dulin

    Publicat 2013
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  3. 3
    Glucocorticoid Receptor Activity Contributes to Resistance to Androgen-Targeted Therapy in Prostate Cancer

    Glucocorticoid Receptor Activity Contributes to Resistance to Androgen-Targeted Therapy in Prostate Cancer per Masis Isikbay, Kristen Otto, Steven Kregel, Jacob Kach, Yi Cai, Donald J. Vander Griend, Suzanne D. Conzen, Russell Z. Szmulewitz

    Publicat 2014
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  4. 4
    Sox2 Is an Androgen Receptor-Repressed Gene That Promotes Castration-Resistant Prostate Cancer

    Sox2 Is an Androgen Receptor-Repressed Gene That Promotes Castration-Resistant Prostate Cancer per Steven Kregel, Kyle J. Kiriluk, Alex M. Rosen, Yi Cai, Edwin E. Reyes, Kristen Otto, Westin R. Tom, Gladell P. Paner, Russell Z. Szmulewitz, Donald J. Vander Griend

    Publicat 2013
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  5. 5
    Acquired resistance to the second-generation androgen receptor antagonist enzalutamide in castration-resistant prostate cancer

    Acquired resistance to the second-generation androgen receptor antagonist enzalutamide in castration-resistant prostate cancer per Steven Kregel, James L. Chen, Westin R. Tom, Venkatesh Krishnan, Jacob Kach, Hannah Brechka, Tim Fessenden, Masis Isikbay, Gladell P. Paner, Russell Z. Szmulewitz, Donald J. Vander Griend

    Publicat 2016
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  6. 6
    Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment

    Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment per Steven Kregel, Chao Wang, Xin Han, Lanbo Xiao, Ester Fernández‐Salas, Pushpinder Bawa, Brooke L. McCollum, Kari Wilder-Romans, Ingrid J. Apel, Xuhong Cao, Corey Speers, Shaomeng Wang, Arul M. Chinnaiyan

    Publicat 2020
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  7. 7
    Biologically informed deep neural network for prostate cancer discovery

    Biologically informed deep neural network for prostate cancer discovery per Haitham Elmarakeby, Justin H. Hwang, Rand Arafeh, Jett Crowdis, Sydney Gang, David Liu, Saud H. AlDubayan, Keyan Salari, Steven Kregel, Camden Richter, Taylor E. Arnoff, Jihye Park, William C. Hahn, Eliezer M. Van Allen

    Publicat 2021
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  8. 8
    PD-L1 expression on circulating tumor cells and platelets in patients with metastatic breast cancer

    PD-L1 expression on circulating tumor cells and platelets in patients with metastatic breast cancer per Elizabeth P. Darga, Emily M. Dolce, Fang Fang, Kelley M. Kidwell, Christina L. Gersch, Steven Kregel, Dafydd G. Thomas, Anoop Gill, Martha E. Brown, Steven Gross, Mark C. Connelly, Michael Holinstat, Erin F. Cobain, James M. Rae, Daniel F. Hayes, Costanza Paoletti

    Publicat 2021
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  9. 9
    SOX2 mediates metabolic reprogramming of prostate cancer cells

    SOX2 mediates metabolic reprogramming of prostate cancer cells per Larischa de Wet, Anthony Williams, Marc Gillard, Steven Kregel, Sophia Lamperis, Lisa C. Gutgesell, Jordan E. Vellky, Ryan M. Brown, Kelly O. Conger, Gladell P. Paner, Heng Wang, Elizabeth A. Platz, Angelo M. De Marzo, Ping Mu, Jonathan L. Coloff, Russell Z. Szmulewitz, Donald J. Vander Griend

    Publicat 2022
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  10. 10
    Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer

    Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer per Weiguo Xiang, Lijie Zhao, Xin Han, Tianfeng Xu, Steven Kregel, Mi Wang, Bukeyan Miao, Chong Qin, Mingliang Wang, Donna McEachern, Jianfeng Lü, Longchuan Bai, Chao‐Yie Yang, Paul D. Kirchhoff, John Takyi‐Williams, Lu Wang, Bo Wen, Duxin Sun, Mark A. Ator, Robert McKean, Arul M. Chinnaiyan, Shaomeng Wang

    Publicat 2023
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  11. 11
    The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression

    The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression per Yashar S. Niknafs, Sumin Han, Teng Ma, Corey Speers, Chao Zhang, Kari Wilder-Romans, Matthew K. Iyer, Sethuramasundaram Pitchiaya, Rohit Malik, Yasuyuki Hosono, John R. Prensner, Anton Poliakov, Udit Singhal, Lanbo Xiao, Steven Kregel, Ronald F. Siebenaler, Shuang G. Zhao, Michaël Uhl, Alexander Gawronski, Daniel F. Hayes, Lori J. Pierce, Xuhong Cao, Colin C. Collins, Rolf Backofen, Cenk S. Sahinalp, James M. Rae, Arul M. Chinnaiyan, Felix Y. Feng

    Publicat 2016
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  12. 12
    Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)

    Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC) per Paige J. Monsen, Prashant V. Bommi, Arabela A. Grigorescu, Kristen L. Lauing, Yingyu Mao, P Berardi, Lijie Zhai, Ohiowele Ojo, Manon Penco-Campillo, Tad H. Koch, Michael Egozi, Sonam Jha, Sara F. Dunne, Hong Jiang, Guiqin Song, Zhang Fei, Steven Kregel, Ali Vaziri‐Gohar, Sean W. Fanning, Pilar Sánchez‐Gómez, Jacob M. Allen, Bakhtiar Yamini, Rimas V. Lukas, Derek A. Wainwright, Gary E. Schiltz

    Publicat 2025
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  13. 13
    Targeting transcriptional regulation of SARS-CoV-2 entry factors<i>ACE2</i>and<i>TMPRSS2</i>

    Targeting transcriptional regulation of SARS-CoV-2 entry factors<i>ACE2</i>and<i>TMPRSS2</i> per Yuanyuan Qiao, Xiaoming Wang, Rahul Mannan, Sethuramasundaram Pitchiaya, Yuping Zhang, Jesse W. Wotring, Lanbo Xiao, Dan R. Robinson, Yi‐Mi Wu, Jean C. Tien, Xuhong Cao, Stephanie A. Simko, Ingrid J. Apel, Pushpinder Bawa, Steven Kregel, Sathiya Pandi Narayanan, Gregory Raskind, Stephanie J. Ellison, Abhijit Parolia, Sylvia Zelenka-Wang, Lisa McMurry, Fengyun Su, Rui Wang, Yunhui Cheng, Andrew Delekta, Zejie Mei, Carla D. Pretto, Shaomeng Wang, Rohit Mehra, Jonathan Z. Sexton, Arul M. Chinnaiyan

    Publicat 2020
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  14. 14
    Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer

    Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer per Alfonso Urbanucci, Stefan J. Barfeld, Ville Kytölä, Harri M. Itkonen, Ilsa M. Coleman, Daniel Vodák, Liisa Sjöblom, Xia Sheng, Teemu Tolonen, Sarah Minner, Christoph Burdelski, Kati Kivinummi, Annika Kohvakka, Steven Kregel, Mandeep Takhar, Mohammed Alshalalfa, Elai Davicioni, Nicholas Erho, Paul Lloyd, R. Jeffrey Karnes, Ashley E. Ross, Edward M. Schaeffer, Donald J. Vander Griend, Stefan Knapp, Eva Corey, Felix Y. Feng, Peter S. Nelson, Fahri Saatcioglu, Karen E. Knudsen, Teuvo L.J. Tammela, Guido Sauter, Thorsten Schlomm, Matti Nykter, Tapio Visakorpi, Ian G. Mills

    Publicat 2017
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  15. 15
    Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer

    Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer per Lanbo Xiao, Abhijit Parolia, Yuanyuan Qiao, Pushpinder Bawa, Sanjana Eyunni, Rahul Mannan, Sandra E. Carson, Yu‐Sun Chang, Xiaoju Wang, Yuping Zhang, Josh N. Vo, Steven Kregel, Stephanie A. Simko, Andrew Delekta, Mustapha Jaber, Heng Zheng, Ingrid J. Apel, Lisa McMurry, Fengyun Su, Rui Wang, Sylvia Zelenka-Wang, Sanjita Sasmal, Leena Khare, Subhendu Mukherjee, Chandrasekhar Abbineni, Kiran Aithal, Mital S. Bhakta, Jay Ghurye, Xuhong Cao, Nora M. Navone, Alexey I. Nesvizhskii, Rohit Mehra, Ulka N. Vaishampayan, Marco Blanchette, Yuzhuo Wang, Susanta Samajdar, Murali Ramachandra, Arul M. Chinnaiyan

    Publicat 2021
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