Search Results - Steven H. Kleinstein

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  1. 1
    Practical guidelines for B-cell receptor repertoire sequencing analysis

    Practical guidelines for B-cell receptor repertoire sequencing analysis by Gur Yaari, Steven H. Kleinstein

    Published 2015
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  2. 2
    A spectral clustering-based method for identifying clones from high-throughput B cell repertoire sequencing data

    A spectral clustering-based method for identifying clones from high-throughput B cell repertoire sequencing data by Nima Nouri, Steven H. Kleinstein

    Published 2018
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  3. 3
    Somatic hypermutation analysis for improved identification of B cell clonal families from next-generation sequencing data

    Somatic hypermutation analysis for improved identification of B cell clonal families from next-generation sequencing data by Nima Nouri, Steven H. Kleinstein

    Published 2020
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  4. 4
    Cutting Edge: Ig H Chains Are Sufficient to Determine Most B Cell Clonal Relationships

    Cutting Edge: Ig H Chains Are Sufficient to Determine Most B Cell Clonal Relationships by Julian Q. Zhou, Steven H. Kleinstein

    Published 2019
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  5. 5
    Quantifying selection in high-throughput Immunoglobulin sequencing data sets

    Quantifying selection in high-throughput Immunoglobulin sequencing data sets by Gur Yaari, Mohamed Uduman, Steven H. Kleinstein

    Published 2012
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  6. 6
    Estimating Hypermutation Rates from Clonal Tree Data

    Estimating Hypermutation Rates from Clonal Tree Data by Steven H. Kleinstein, Yoram Louzoun, Mark J. Shlomchik

    Published 2003
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  7. 7
    Cell subset prediction for blood genomic studies

    Cell subset prediction for blood genomic studies by Christopher R. Bolen, Mohamed Uduman, Steven H. Kleinstein

    Published 2011
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  8. 8
    Predictive overfitting in immunological applications: Pitfalls and solutions

    Predictive overfitting in immunological applications: Pitfalls and solutions by Jeremy P. Gygi, Steven H. Kleinstein, Leying Guan

    Published 2023
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  9. 9
    Phylogenetic analysis of migration, differentiation, and class switching in B cells

    Phylogenetic analysis of migration, differentiation, and class switching in B cells by Kenneth B. Hoehn, Oliver G. Pybus, Steven H. Kleinstein

    Published 2022
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  10. 10
    Computational resources for high-dimensional immune analysis from the Human Immunology Project Consortium

    Computational resources for high-dimensional immune analysis from the Human Immunology Project Consortium by Vladimir Brusić, Raphaël Gottardo, Steven H. Kleinstein, Mark M. Davis

    Published 2014
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  11. 11
    Automated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles

    Automated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles by Daniel Gadala-Maria, Gur Yaari, Mohamed Uduman, Steven H. Kleinstein

    Published 2015
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  12. 12
    Improved methods for detecting selection by mutation analysis of Ig V region sequences

    Improved methods for detecting selection by mutation analysis of Ig V region sequences by Uri Hershberg, Mohamed Uduman, Mark J. Shlomchik, Steven H. Kleinstein

    Published 2008
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  13. 13
    Quantitative set analysis for gene expression: a method to quantify gene set differential expression including gene-gene correlations

    Quantitative set analysis for gene expression: a method to quantify gene set differential expression including gene-gene correlations by Gur Yaari, Christopher R. Bolen, Juilee Thakar, Steven H. Kleinstein

    Published 2013
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  14. 14
    Dynamic expression profiling of type I and type III interferon-stimulated hepatocytes reveals a stable hierarchy of gene expression

    Dynamic expression profiling of type I and type III interferon-stimulated hepatocytes reveals a stable hierarchy of gene expression by Christopher R. Bolen, Siyuan Ding, Michael D. Robek, Steven H. Kleinstein

    Published 2013
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  15. 15
    Supervised fine-tuning of pre-trained antibody language models improves antigen specificity prediction

    Supervised fine-tuning of pre-trained antibody language models improves antigen specificity prediction by Meng Wang, Jonathan Patsenker, Henry Li, Yuval Kluger, Steven H. Kleinstein

    Published 2025
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  16. 16
    TLR4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A Differentially Regulate Effector and Memory CD8+ T Cell Differentiation

    TLR4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A Differentially Regulate Effector and Memory CD8+ T Cell Differentiation by Weiguo Cui, Nikhil S. Joshi, Ying Liu, Hailong Meng, Steven H. Kleinstein, Susan M. Kaech

    Published 2014
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  17. 17
    Hierarchical Clustering Can Identify B Cell Clones with High Confidence in Ig Repertoire Sequencing Data

    Hierarchical Clustering Can Identify B Cell Clones with High Confidence in Ig Repertoire Sequencing Data by Namita T. Gupta, Kristofor Adams, Adrian W. Briggs, Sonia Timberlake, François Vigneault, Steven H. Kleinstein

    Published 2017
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  18. 18
    Polycomb Repressive Complex 2-Mediated Chromatin Repression Guides Effector CD8 + T Cell Terminal Differentiation and Loss of Multipotency

    Polycomb Repressive Complex 2-Mediated Chromatin Repression Guides Effector CD8 + T Cell Terminal Differentiation and Loss of Multipotency by Simon M. Gray, Robert A. Amezquita, Tianxia Guan, Steven H. Kleinstein, Susan M. Kaech

    Published 2017
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  19. 19
    The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales

    The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales by Gur Yaari, Jennifer I. C. Benichou, Jason A. Vander Heiden, Steven H. Kleinstein, Yoram Louzoun

    Published 2015
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  20. 20
    Lambda and alpha interferons inhibit hepatitis B virus replication through a common molecular mechanism but with different in vivo activities

    Lambda and alpha interferons inhibit hepatitis B virus replication through a common molecular mechanism but with different in vivo activities by Nicole E. Pagliaccetti, Esther N. Chu, Christopher R. Bolen, Steven H. Kleinstein, Michael D. Robek

    Published 2010
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