Resultats de la cerca - Steven Gendreau

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  1. 1
    Pictilisib PI3Kinase inhibitor (a phosphatidylinositol 3-kinase [PI3K] inhibitor) plus paclitaxel for the treatment of hormone receptor-positive, HER2-negative, locally recurrent, or metastatic breast cancer: interim analysis of the multicentre, placebo-controlled, phase II randomised PEGGY study

    Pictilisib PI3Kinase inhibitor (a phosphatidylinositol 3-kinase [PI3K] inhibitor) plus paclitaxel for the treatment of hormone receptor-positive, HER2-negative, locally recurrent,... per Peter Vuylsteke, Manon Huizing, Katarína Petráková, Rebecca Roylance, Robert Laing, Stephen Chan, F. Abell, Steven Gendreau, Isabelle Rooney, Doris Apt, Jing Zhou, Stina Mui Singel, Louis Fehrenbacher

    Publicat 2016
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  2. 2
    A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer

    A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer per Patrick Schöffski, Sara Cresta, Ingrid A. Mayer, Hans Wildiers, Silvia Damian, Steven Gendreau, Isabelle Rooney, Kari M. Morrissey, Jill M. Spoerke, Vivian Ng, Stina Mui Singel, Eric P. Winer

    Publicat 2018
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  3. 3
    Chromosomal Instability Estimation Based on Next Generation Sequencing and Single Cell Genome Wide Copy Number Variation Analysis

    Chromosomal Instability Estimation Based on Next Generation Sequencing and Single Cell Genome Wide Copy Number Variation Analysis per Stephanie Greene, Angel E. Dago, Laura Leitz, Yipeng Wang, Jerry Lee, Shannon L. Werner, Steven Gendreau, Premal H. Patel, Shidong Jia, Liangxuan Zhang, Eric Tucker, Michael Malchiodi, Ryon P. Graf, Ryan Dittamore, Dena Marrinucci, Mark Landers

    Publicat 2016
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  4. 4
    Low-pass Whole-genome Sequencing of Circulating Cell-free DNA Demonstrates Dynamic Changes in Genomic Copy Number in a Squamous Lung Cancer Clinical Cohort

    Low-pass Whole-genome Sequencing of Circulating Cell-free DNA Demonstrates Dynamic Changes in Genomic Copy Number in a Squamous Lung Cancer Clinical Cohort per Xiaoji Chen, Ching‐Wei Chang, Jill M. Spoerke, Kathryn E. Yoh, Vidushi Kapoor, Charles Baudo, Junko Aimi, Mamie Yu, May M.Y. Liang-Chu, Rebecca Suttmann, Ling‐Yuh Huw, Steven Gendreau, Craig Cummings, Mark R. Lackner

    Publicat 2019
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  5. 5
    Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant

    Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant per Jill M. Spoerke, Steven Gendreau, Kimberly Walter, Jiaheng Qiu, Timothy R. Wilson, Heidi Savage, Junko Aimi, Mika K. Derynck, Meng Chen, Iris T. Chan, Lukas C. Amler, Garret M. Hampton, Stephen Johnston, Ian E. Krop, Peter Schmid, Mark R. Lackner

    Publicat 2016
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  6. 6
    Randomized Phase II Study Evaluating Akt Blockade with Ipatasertib, in Combination with Abiraterone, in Patients with Metastatic Prostate Cancer with and without PTEN Loss

    Randomized Phase II Study Evaluating Akt Blockade with Ipatasertib, in Combination with Abiraterone, in Patients with Metastatic Prostate Cancer with and without PTEN Loss per Johann S. de Bono, Ugo De Giorgi, Daniel Nava Rodrigues, Christophe Massard, Sergio Bracarda, Albert Font, José Ángel Arranz Arija, Kent C. Shih, George Daniel Rădăvoi, Na Xu, Wai Yee Chan, Han Ma, Steven Gendreau, Ruth Riisnaes, Premal H. Patel, Daniel Maslyar, Viorel Jinga

    Publicat 2018
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  7. 7
    PTEN loss as a predictive biomarker for the Akt inhibitor ipatasertib combined with abiraterone acetate in patients with metastatic castration-resistant prostate cancer (mCRPC)

    PTEN loss as a predictive biomarker for the Akt inhibitor ipatasertib combined with abiraterone acetate in patients with metastatic castration-resistant prostate cancer (mCRPC) per Johann S. de Bono, Ugo De Giorgi, Christophe Massard, Sergio Bracarda, Daniel Nava Rodrigues, Ivo Kocák, Albert Font, J.Á. Arranz Arija, Kent C. Shih, George Daniel Rădăvoi, Wandong Yu, Wen‐Ching Chan, Steven Gendreau, L. Zhang, Ruth Riisnaes, Matthew Wongchenko, Daniel Maslyar, Viorel Jinga

    Publicat 2016
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  8. 8
    Phase II Randomized Preoperative Window-of-Opportunity Study of the PI3K Inhibitor Pictilisib Plus Anastrozole Compared With Anastrozole Alone in Patients With Estrogen Receptor–Positive Breast Cancer

    Phase II Randomized Preoperative Window-of-Opportunity Study of the PI3K Inhibitor Pictilisib Plus Anastrozole Compared With Anastrozole Alone in Patients With Estrogen Receptor–Po... per Peter Schmid, Sarah E. Pinder, Duncan Wheatley, Jane Macaskill, Charles Zammit, Jennifer J. Hu, R. Jordan Price, Nigel Bundred, Sirwan Hadad, Alice Shia, Shah-Jalal Sarker, Louise Lim, Patrycja Gazińska, Natalie Woodman, Darren Korbie, Matt Trau, Paul N. Mainwaring, Steven Gendreau, Mark R. Lackner, Mika K. Derynck, Timothy R. Wilson, H. EUGENE BUTLER, Gemma Earl, Peter J. Parker, Arnie Purushotham, Alastair M. Thompson

    Publicat 2016
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  9. 9
    Analytical Validation of a Hybrid Capture–Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA

    Analytical Validation of a Hybrid Capture–Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA per Travis Clark, Jon Chung, Mark Kennedy, Jason D. Hughes, Niru Chennagiri, Daniel S. Lieber, Bernard J. Fendler, Lauren Young, Mandy Zhao, Michael J. Coyne, Virginia Breese, Geneva Young, Amy Donahue, Dean C. Pavlick, Alyssa Tsiros, Timothy A Brennan, Shan Zhong, Tariq I. Mughal, Mark Bailey, Jie He, Steven Roels, Garrett M. Frampton, Jill M. Spoerke, Steven Gendreau, Mark R. Lackner, Erica Schleifman, Eric Peters, Jeffrey S. Ross, Siraj M. Ali, Vincent A. Miller, Jeffrey P. Gregg, Philip J. Stephens, Allison W. Welsh, Geoff Otto, Doron Lipson

    Publicat 2018
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