Resultados de procura - Steven A. Roberts

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  1. 1
    Hypermutation in human cancer genomes: footprints and mechanisms

    Hypermutation in human cancer genomes: footprints and mechanisms por Steven A. Roberts, Dmitry A. Gordenin

    Publicado 2014
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  2. 2
    Clustered and genome‐wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness

    Clustered and genome‐wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness por Steven A. Roberts, Dmitry A. Gordenin

    Publicado 2014
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  3. 3
    Chromosomal landscape of UV damage formation and repair at single-nucleotide resolution

    Chromosomal landscape of UV damage formation and repair at single-nucleotide resolution por Peng Mao, Michael J. Smerdon, Steven A. Roberts, John J. Wyrick

    Publicado 2016
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  4. 4
    UV‐Induced DNA Damage and Mutagenesis in Chromatin

    UV‐Induced DNA Damage and Mutagenesis in Chromatin por Peng Mao, John J. Wyrick, Steven A. Roberts, Michael J. Smerdon

    Publicado 2016
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  5. 5
    Specificity of the dRP/AP Lyase of Ku Promotes Nonhomologous End Joining (NHEJ) Fidelity at Damaged Ends

    Specificity of the dRP/AP Lyase of Ku Promotes Nonhomologous End Joining (NHEJ) Fidelity at Damaged Ends por Natasha T. Strande, Steven A. Roberts, Sehyun Oh, Eric A. Hendrickson, Dale A. Ramsden

    Publicado 2012
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  6. 6
    Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function

    Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function por Marina Martín, Aoi Hiroyasu, R. Marena Guzman, Steven A. Roberts, Alan G. Goodman

    Publicado 2018
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  7. 7
    Nucleosome positions establish an extended mutation signature in melanoma

    Nucleosome positions establish an extended mutation signature in melanoma por Alexander J. Brown, Peng Mao, Michael J. Smerdon, John J. Wyrick, Steven A. Roberts

    Publicado 2018
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  8. 8
    Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent

    Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent por Kin Chan, Joan F. Sterling, Steven A. Roberts, Ashok S. Bhagwat, Michael A. Resnick, Dmitry A. Gordenin

    Publicado 2012
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  9. 9
    Toxicodynamics of Itraconazole: Implications for Therapeutic Drug Monitoring

    Toxicodynamics of Itraconazole: Implications for Therapeutic Drug Monitoring por Jodi M. Lestner, Steven A. Roberts, Caroline B. Moore, Susan J. Howard, David W. Denning, William Hope

    Publicado 2009
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  10. 10
    APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast

    APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast por Natalie Saini, Steven A. Roberts, Joan F. Sterling, Ewa P. Malc, Piotr A. Mieczkowski, Dmitry A. Gordenin

    Publicado 2017
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  11. 11
    Repair of base damage within break-induced replication intermediates promotes kataegis associated with chromosome rearrangements

    Repair of base damage within break-induced replication intermediates promotes kataegis associated with chromosome rearrangements por Rajula Elango, Beth Osia, Victoria Harcy, Ewa P. Malc, Piotr A. Mieczkowski, Steven A. Roberts, Anna Malkova

    Publicado 2019
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  12. 12
    Ku is a 5′-dRP/AP lyase that excises nucleotide damage near broken ends

    Ku is a 5′-dRP/AP lyase that excises nucleotide damage near broken ends por Steven A. Roberts, Natasha T. Strande, Martin D. Burkhalter, Christina Strom, Jody M. Havener, Paul Hasty, Dale A. Ramsden

    Publicado 2010
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  13. 13
    APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions

    APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions por Marat D. Kazanov, Steven A. Roberts, Paz Polak, J Stamatoyannopoulos, Leszek J. Klimczak, Dmitry A. Gordenin, Shamil Sunyaev

    Publicado 2015
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  14. 14
    APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication

    APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication por James I. Hoopes, Luis M. Cortez, Tony M. Mertz, Ewa P. Malc, Piotr A. Mieczkowski, Steven A. Roberts

    Publicado 2016
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  15. 15
    Break-Induced Replication Is a Source of Mutation Clusters Underlying Kataegis

    Break-Induced Replication Is a Source of Mutation Clusters Underlying Kataegis por Cynthia J. Sakofsky, Steven A. Roberts, Ewa P. Malc, Piotr A. Mieczkowski, Michael A. Resnick, Dmitry A. Gordenin, Anna Malkova

    Publicado 2014
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  16. 16
    Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity

    Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity por Peng Mao, Alexander J. Brown, Ewa P. Malc, Piotr A. Mieczkowski, Michael J. Smerdon, Steven A. Roberts, John J. Wyrick

    Publicado 2017
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  17. 17
    ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma

    ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma por Peng Mao, Alexander J. Brown, Shingo Esaki, Svetlana Lockwood, Gregory M.K. Poon, Michael J. Smerdon, Steven A. Roberts, John J. Wyrick

    Publicado 2018
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  18. 18
    APOBEC3A is a prominent cytidine deaminase in breast cancer

    APOBEC3A is a prominent cytidine deaminase in breast cancer por Luis M. Cortez, Amber L. Brown, Madeline A. Dennis, Christopher D. Collins, Alexander J. Brown, Debra Mitchell, Tony M. Mertz, Steven A. Roberts

    Publicado 2019
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  19. 19
    APOBEC3A deaminates CTG hairpin loops to promote fragility and instability of expanded CAG/CTG repeats

    APOBEC3A deaminates CTG hairpin loops to promote fragility and instability of expanded CAG/CTG repeats por Rebecca E. Brown, Margo Coxon, Bianca Larsen, Maxwell J. Allison, Ariana Chadha, Isabelle Mittelstadt, Tony M. Mertz, Steven A. Roberts, Catherine H. Freudenreich

    Publicado 2025
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  20. 20
    Mechanistic basis for microhomology identification and genome scarring by polymerase theta

    Mechanistic basis for microhomology identification and genome scarring by polymerase theta por Juan Carvajal-Garcia, Jang-Eun Cho, Pablo Carvajal-Garcia, Wanjuan Feng, Richard D. Wood, Jeff Sekelsky, Gaorav P. Gupta, Steven A. Roberts, Dale A. Ramsden

    Publicado 2020
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