Search Results - Steve Stegen

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  1. 1
    The skeletal vascular system – Breathing life into bone tissue

    The skeletal vascular system – Breathing life into bone tissue by Steve Stegen, Geert Carmeliet

    Published 2017
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  2. 2
    Hypoxia, hypoxia-inducible transcription factors and oxygen-sensing prolyl hydroxylases in bone development and homeostasis

    Hypoxia, hypoxia-inducible transcription factors and oxygen-sensing prolyl hydroxylases in bone development and homeostasis by Steve Stegen, Geert Carmeliet

    Published 2019
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  3. 3
    Bringing new life to damaged bone: The importance of angiogenesis in bone repair and regeneration

    Bringing new life to damaged bone: The importance of angiogenesis in bone repair and regeneration by Steve Stegen, Nick van Gastel, Geert Carmeliet

    Published 2014
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  4. 4
    Amino acid metabolism in skeletal cells

    Amino acid metabolism in skeletal cells by Claire-Sophie Devignes, Geert Carmeliet, Steve Stegen

    Published 2022
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  5. 5
    The serine synthesis pathway drives osteoclast differentiation through epigenetic regulation of NFATc1 expression

    The serine synthesis pathway drives osteoclast differentiation through epigenetic regulation of NFATc1 expression by Steve Stegen, Karen Moermans, Ingrid Stockmans, Bernard Thienpont, Geert Carmeliet

    Published 2024
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  6. 6
    De novo serine synthesis regulates chondrocyte proliferation during bone development and repair

    De novo serine synthesis regulates chondrocyte proliferation during bone development and repair by Steve Stegen, Shauni Loopmans, Ingrid Stockmans, Karen Moermans, Peter Carmeliet, Geert Carmeliet

    Published 2022
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  7. 7
    Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH-Induced Bone Anabolism in Male Mice

    Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH-Induced Bone Anabolism in Male Mice by Steve Stegen, Claire-Sophie Devignes, Sophie Torrekens, Riet Van Looveren, Peter Carmeliet, Geert Carmeliet

    Published 2020
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  8. 8
    Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin

    Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin by Steve Stegen, Ingrid Stockmans, Karen Moermans, Bernard Thienpont, Patrick H. Maxwell, Peter Carmeliet, Geert Carmeliet

    Published 2018
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  9. 9
    Nestin-GFP transgene labels skeletal progenitors in the periosteum

    Nestin-GFP transgene labels skeletal progenitors in the periosteum by Guillaume Tournaire, Steve Stegen, Greta Giacomini, Ingrid Stockmans, Karen Moermans, Geert Carmeliet, Nick van Gastel

    Published 2020
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  10. 10
    Expansion of Murine Periosteal Progenitor Cells with Fibroblast Growth Factor 2 Reveals an Intrinsic Endochondral Ossification Program Mediated by Bone Morphogenetic Protein 2

    Expansion of Murine Periosteal Progenitor Cells with Fibroblast Growth Factor 2 Reveals an Intrinsic Endochondral Ossification Program Mediated by Bone Morphogenetic Protein 2 by Nick van Gastel, Steve Stegen, Ingrid Stockmans, Karen Moermans, Jan Schrooten, Daniel Graf, Frank P. Luyten, Geert Carmeliet

    Published 2014
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  11. 11
    Glutamine Metabolism Controls Chondrocyte Identity and Function

    Glutamine Metabolism Controls Chondrocyte Identity and Function by Steve Stegen, Gianmarco Rinaldi, Shauni Loopmans, Ingrid Stockmans, Karen Moermans, Bernard Thienpont, Sarah‐Maria Fendt, Peter Carmeliet, Geert Carmeliet

    Published 2020
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  12. 12
    The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes

    The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes by Shauni Loopmans, Kateřina Rohlenová, Thomas Van Brussel, Ingrid Stockmans, Karen Moermans, Nicolas Peredo, Peter Carmeliet, Diether Lambrechts, Steve Stegen, Geert Carmeliet

    Published 2025
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  13. 13
    Breast cancer cells rely on environmental pyruvate to shape the metastatic niche

    Breast cancer cells rely on environmental pyruvate to shape the metastatic niche by Ilaria Elia, Matteo Rossi, Steve Stegen, Dorien Broekaert, Ginevra Doglioni, Marit van Gorsel, Ruben Boon, Carmen Escalona‐Noguero, Sophie Torrekens, Catherine M. Verfaillie, Erik Verbeken, Geert Carmeliet, Sarah‐Maria Fendt

    Published 2019
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  14. 14
    Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways

    Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways by Javed K. Manesia, Zhuofei Xu, Dorien Broekaert, Ruben Boon, Alexander R. van Vliet, Guy Eelen, Thomas Vanwelden, Steve Stegen, Nick van Gastel, Alberto Pascual-Montano, Sarah‐Maria Fendt, Geert Carmeliet, Peter Carmeliet, Satish Khurana, Catherine M. Verfaillie

    Published 2015
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  15. 15
    HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival

    HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival by Steve Stegen, Nick van Gastel, Guy Eelen, Bart Ghesquière, Flora D’Anna, Bernard Thienpont, Jermaine Goveia, Sophie Torrekens, Riet Van Looveren, Frank P. Luyten, Patrick H. Maxwell, Ben Wielockx, Diether Lambrechts, Sarah‐Maria Fendt, Peter Carmeliet, Geert Carmeliet

    Published 2016
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  16. 16
    HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

    HIF-1α metabolically controls collagen synthesis and modification in chondrocytes by Steve Stegen, Kjell Laperre, Guy Eelen, Gianmarco Rinaldi, Peter Fraisl, Sophie Torrekens, Riet Van Looveren, Shauni Loopmans, Geert Bultynck, Stefan Vinckier, Filip Meersman, Patrick H. Maxwell, Jyoti Rai, MaryAnn Weis, David R. Eyre, Bart Ghesquière, Sarah‐Maria Fendt, Peter Carmeliet, Geert Carmeliet

    Published 2019
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  17. 17
    Lipid availability determines fate of skeletal progenitor cells via SOX9

    Lipid availability determines fate of skeletal progenitor cells via SOX9 by Nick van Gastel, Steve Stegen, Guy Eelen, Sandra Schoors, Aurélie Carlier, Veerle W. Daniëls, Ninib Baryawno, Dariusz Przybylski, Maarten Depypere, Pieter‐Jan Stiers, Dennis Lambrechts, Riet Van Looveren, Sophie Torrekens, Azeem Sharda, Patrizia Agostinis, Diether Lambrechts, Frederik Maes, Johan Swinnen, Liesbet Geris, Hans Van Oosterwyck, Bernard Thienpont, Peter Carmeliet, David T. Scadden, Geert Carmeliet

    Published 2020
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  18. 18
    Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis

    Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis by Kateřina Rohlenová, Jermaine Goveia, Melissa García‐Caballero, Abhishek Subramanian, Joanna Kalucka, Lucas Treps, Kim D. Falkenberg, Laura de Rooij, Yingfeng Zheng, Lin Lin, Liliana Sokol, Laure-Anne Teuwen, Vincent Geldhof, Federico Taverna, Andreas Pircher, Lena‐Christin Conradi, Shawez Khan, Steve Stegen, Dena Panovska, Frederik De Smet, Frank J. T. Staal, René McLaughlin, Stefan Vinckier, Tine Van Bergen, Nadine Ectors, Patrik De Haes, Jian Wang, Lars Bolund, Luc Schoonjans, Tobias K. Karakach, Huanming Yang, Geert Carmeliet, Yizhi Liu, Bernard Thienpont, Mieke Dewerchin, Guy Eelen, Xuri Li, Yonglun Luo, Peter Carmeliet

    Published 2020
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