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A Phase I Dose-Finding Study of 5-Azacytidine in Combination with Sodium Phenylbutyrate in Patients with Refractory Solid Tumors 由 Jianqing Lin, Jill Gilbert, Michelle A. Rudek, James A. Zwiebel, Steve Gore, Anchalee Jiemjit, Ming Zhao, Sharyn D. Baker, Richard F. Ambinder, James G. Herman, Ross C. Donehower, Michael A. Carducci
出版 2009Artigo
相关主题
Biology
DNA methylation
Gene
Gene expression
Histone
Acetylation
Azacitidine
Biochemistry
Cancer epigenetics
Chemotherapy
Chromatin
Chromatin remodeling
Clinical trial
Combination therapy
CpG site
Epigenetic regulation of neurogenesis
Epigenetics
Epigenetics of physical exercise
Gene silencing
Genetics
Histone deacetylase
Histone deacetylase inhibitor
Histone methyltransferase
Internal medicine
Medicine
Neutropenia
Oncology
Pharmacodynamics
Pharmacokinetics
Pharmacology