Search Results - Stefania Segditsas
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1
Severe polyposis in Apc<sup>1322T</sup>mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker<i>Lgr5</i> by Annabelle Lewis, Stefania Segditsas, Maesha Deheragoda, Patrick J. Pollard, Rosemary Jeffery, Emma Nye, Helen Lockstone, Hayley L. Belnoue-Davis, Susan K. Clark, G. W. H. Stamp, Richard Poulsom, Nicholas A. Wright, Ian Tomlinson
Published 2010Artigo -
2
Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice by Stefania Segditsas, Oliver M. Sieber, Maesha Deheragoda, Philip East, Andrew Rowan, Rosemary Jeffery, Emma Nye, Susan K. Clark, Bradley Spencer‐Dene, Gordon Stamp, Richard Poulsom, Nirosha Suraweera, Andrew Silver, Mohammad Ilyas, Ian Tomlinson
Published 2008Artigo -
3
Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1 by Emma Jaeger, Simon J. Leedham, Annabelle Lewis, Stefania Segditsas, Martin Becker, Pedro Rodenas Cuadrado, Hayley L. Belnoue-Davis, Kulvinder Kaur, Karl Heinimann, Kimberley Howarth, James E. East, Jenny C. Taylor, Huw Thomas, Ian Tomlinson
Published 2012Artigo -
4
A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts by Simon J. Leedham, Pedro Rodenas-Cuadrado, Kimberley Howarth, Annabelle Lewis, Sreelakshmi Mallappa, Stefania Segditsas, Hayley L. Belnoue-Davis, Rosemary Jeffery, Manuel Rodriguez‐Justo, Satish Keshav, Simon Travis, Trevor A. Graham, James E. East, Susan K. Clark, Ian Tomlinson
Published 2012Artigo -
5
The Apc1322T Mouse Develops Severe Polyposis Associated With Submaximal Nuclear β-Catenin Expression by Patrick J. Pollard, Maesha Deheragoda, Stefania Segditsas, Annabelle Lewis, Andrew Rowan, Kimberley Howarth, Lisa Willis, Emma Nye, Amy E. McCart Reed, Nikki Mandir, Andrew Silver, Robert A. Goodlad, G. W. H. Stamp, Matthew E. Cockman, Philip East, Bradley Spencer‐Dene, Richard Poulsom, Nicholas A. Wright, Ian Tomlinson
Published 2009Artigo -
6
PHLDA1 Expression Marks the Putative Epithelial Stem Cells and Contributes to Intestinal Tumorigenesis by Anuratha Sakthianandeswaren, Michael Christie, Carla D'Andreti, Cary Tsui, Robert N. Jorissen, Shan Li, Nicholas I. Fleming, Peter Gibbs, Lara Lipton, Jordane Malaterre, Robert G. Ramsay, Toby J. Phesse, Matthias Ernst, Rosemary Jeffery, Richard Poulsom, Simon J. Leedham, Stefania Segditsas, Ian Tomlinson, Oliver K. Bernhard, Richard J. Simpson, Francesca Walker, Maree C. Faux, Nicole L. Church, Bruno Catimel, Dustin J. Flanagan, Elizabeth Vincan, Oliver M. Sieber
Published 2011Artigo
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Biology
Genetics
Cancer research
Gene
Wnt signaling pathway
Carcinogenesis
Medicine
Stem cell
Cancer
Catenin
Cell
Cell biology
Colorectal cancer
Crypt
Endocrinology
Internal medicine
Molecular biology
Pathology
Stem cell marker
Adenomatous polyposis coli
BMI1
Basal (medicine)
Beta-catenin
CD44
Cancer stem cell
Cell adhesion
Cell growth
Computer science
Copy-number variation
Ectopic expression