Search Results - Spyros P. Nikas

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  1. 1
    Δ9-Tetrahydrocannabinol acts as a partial agonist/antagonist in mice

    Δ9-Tetrahydrocannabinol acts as a partial agonist/antagonist in mice by Carol A. Paronis, Spyros P. Nikas, Vidyanand G. Shukla, Alexandros Makriyannis

    Published 2012
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  2. 2
    Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal

    Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal by Ailing Li, Xiaoyan Lin, Amey Dhopeshwarkar, Ana C. Thomaz, Lawrence M. Carey, Yingpeng Liu, Spyros P. Nikas, Alexandros Makriyannis, Ken Mackie, Andrea G. Hohmann

    Published 2018
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  3. 3
    Novel 1′,1′-Chain Substituted Hexahydrocannabinols: 9β-Hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a Highly Potent Cannabinoid Receptor 1 (CB1) Agonist

    Novel 1′,1′-Chain Substituted Hexahydrocannabinols: 9β-Hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a Highly Potent Cannabinoid Receptor 1 (CB1) Agonist by Spyros P. Nikas, Shakiru O. Alapafuja, Ioannis Papanastasiou, Carol A. Paronis, Vidyanand G. Shukla, Demetris P. Papahatjis, Anna L. Bowman, H. Aneetha, Xiuwen Han, Alexandros Makriyannis

    Published 2010
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  4. 4
    Sulfonyl Fluoride Inhibitors of Fatty Acid Amide Hydrolase

    Sulfonyl Fluoride Inhibitors of Fatty Acid Amide Hydrolase by Shakiru O. Alapafuja, Spyros P. Nikas, Indu Bharathan, Vidyanand G. Shukla, Mahmoud L. Nasr, Anna L. Bowman, Nikolai Zvonok, Jing Li, Xiaomeng Shi, John R. Engen, Alexandros Makriyannis

    Published 2012
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  5. 5
    Structural basis for activation of CB1 by an endocannabinoid analog

    Structural basis for activation of CB1 by an endocannabinoid analog by Kaavya Krishna Kumar, Michael J. Robertson, Elina Thadhani, Haoqing Wang, Carl‐Mikael Suomivuori, Alexander S. Powers, Lipin Ji, Spyros P. Nikas, Ron O. Dror, Asuka Inoue, Alexandros Makriyannis, Georgios Skiniotis, Brian K. Kobilka

    Published 2023
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  6. 6
    Inhibitor of Fatty Acid Amide Hydrolase Normalizes Cardiovascular Function in Hypertension without Adverse Metabolic Effects

    Inhibitor of Fatty Acid Amide Hydrolase Normalizes Cardiovascular Function in Hypertension without Adverse Metabolic Effects by Grzegorz Godlewski, Shakiru O. Alapafuja, Sándor Bátkai, Spyros P. Nikas, Reşat Çınar, László Offertáler, Douglas Osei‐Hyiaman, Jie Liu, Bani Mukhopadhyay, Judith Harvey‐White, Joseph Tam, Karel Pacák, Jacqueline L. Blankman, Benjamin F. Cravatt, Alexandros Makriyannis, George Kunos

    Published 2010
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  7. 7
    Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity

    Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity by Ozge Gunduz‐Cinar, Kathryn P. MacPherson, Reşat Çınar, Joyonna Gamble‐George, Karen Sugden, Benjamin Williams, G Godlewski, Teniel S Ramikie, Adam X. Gorka, Shakiru O. Alapafuja, Spyros P. Nikas, Alexandros Makriyannis, Richie Poulton, Sachin Patel, Ahmad R. Hariri, Avshalom Caspi, Terrie E. Moffitt, George Kunos, Andrew Holmes

    Published 2012
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  8. 8
    Crystal structures of agonist-bound human cannabinoid receptor CB1

    Crystal structures of agonist-bound human cannabinoid receptor CB1 by Tian Hua, Kiran Vemuri, Spyros P. Nikas, Robert B. Laprairie, Yiran Wu, Lu Qu, Mengchen Pu, Anisha Korde, Shan Jiang, Jo‐Hao Ho, Gye Won Han, Kang Ding, Xuanxuan Li, Haiguang Liu, Michael A. Hanson, Suwen Zhao, Laura Bohn, Alexandros Makriyannis, Raymond C. Stevens, Zhi‐Jie Liu

    Published 2017
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  9. 9
    Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures

    Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures by Tian Hua, Xiaoting Li, Lijie Wu, Christos Iliopoulos‐Tsoutsouvas, Yuxia Wang, Meng Wu, Ling Shen, Christina A. Brust, Spyros P. Nikas, Feng Song, Xiyong Song, Shuguang Yuan, Qianqian Sun, Yiran Wu, Shan Jiang, Travis W. Grim, Othman Benchama, Edward L. Stahl, Nikolai Zvonok, Suwen Zhao, Laura Bohn, Alexandros Makriyannis, Zhi‐Jie Liu

    Published 2020
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