Výsledky vyhledávání - Spengler, Ryan M

Rational Design of Therapeutic siRNAs: Minimizing Off-targeting Potential to Improve the Safety of RNAi Therapy for Huntington's Disease Autor Boudreau, Ryan L, Spengler, Ryan M, Davidson, Beverly L

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Functional microRNAs and target sites are created by lineage-specific transposition Autor Spengler, Ryan M., Oakley, Clayton K., Davidson, Beverly L.

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Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics Autor Suzuki, Hiroshi I., Spengler, Ryan M., Grigelioniene, Giedre, Kobayashi, Tatsuya, Sharp, Phillip A.

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Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts Autor Ramachandran, Shyam, Coffin, Stephanie L., Tang, Tin-Yun, Jobaliya, Chintan D., Spengler, Ryan M., Davidson, Beverly L.

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Adenosine deamination in human transcripts generates novel microRNA binding sites Autor Borchert, Glen M., Gilmore, Brian L., Spengler, Ryan M., Xing, Yi, Lanier, William, Bhattacharya, Debashish, Davidson, Beverly L.

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Structure and activity of putative intronic miRNA promoters Autor Monteys, Alex Mas, Spengler, Ryan M., Wan, Ji, Tecedor, Luis, Lennox, Kimberly A., Xing, Yi, Davidson, Beverly L.

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The long non-coding RNA NEAT1 is elevated in polyglutamine repeat expansion diseases and protects from disease gene-dependent toxicities Autor Cheng, Congsheng, Spengler, Ryan M, Keiser, Megan S, Monteys, Alejandro Mas, Rieders, Julianne M, Ramachandran, Shyam, Davidson, Beverly L

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Rational Design Leads to More Potent RNA Interference Against Hepatitis B Virus: Factors Effecting Silencing Efficiency Autor Keck, Kathy, Volper, Esther M, Spengler, Ryan M, Long, Dang D, Chan, Chi Y, Ding, Ye, McCaffrey, Anton P

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siSPOTR: a tool for designing highly specific and potent siRNAs for human and mouse Autor Boudreau, Ryan L., Spengler, Ryan M., Hylock, Ray H., Kusenda, Brandyn J., Davis, Heather A., Eichmann, David A., Davidson, Beverly L.

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Phospho‐RNA‐seq: a modified small RNA‐seq method that reveals circulating mRNA and lncRNA fragments as potential biomarkers in human plasma Autor Giraldez, Maria D, Spengler, Ryan M, Etheridge, Alton, Goicochea, Annika J, Tuck, Missy, Choi, Sung Won, Galas, David J, Tewari, Muneesh

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Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP Autor Spengler, Ryan M., Zhang, Xiaoming, Cheng, Congsheng, McLendon, Jared M., Skeie, Jessica M., Johnson, Frances L., Davidson, Beverly L., Boudreau, Ryan L.

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Transcriptome-wide Discovery of microRNA Binding Sites in Human Brain Autor Boudreau, Ryan L., Jiang, Peng, Gilmore, Brian L., Spengler, Ryan M., Tirabassi, Rebecca, Nelson, Jay A., Ross, Christopher A., Xing, Yi, Davidson, Beverly L.

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Single nucleotide seed modification restores in vivo tolerability of a toxic artificial miRNA sequence in the mouse brain Autor Monteys, Alex Mas, Spengler, Ryan M., Dufour, Brett D., Wilson, Matt S., Oakley, Clayton K., Sowada, Matt J., McBride, Jodi L., Davidson, Beverly L.

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Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Autor Haring, Catherine T., Bhambhani, Chandan, Brummel, Collin, Jewell, Brittany, Bellile, Emily, Heft Neal, Molly E., Sandford, Erin, Spengler, Ryan M., Bhangale, Apurva, Spector, Matthew E., McHugh, Jonathan, Prince, Mark E., Mierzwa, Michelle, Worden, Francis P., Tewari, Muneesh, Swiecicki, Paul L., Brenner, J. Chad

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Open Problems in Extracellular RNA Data Analysis: Insights From an ERCC Online Workshop Autor Alexander, Roger P., Kitchen, Robert R, Tosar, Juan Pablo, Roth, Matthew, Mestdagh, Pieter, Max, Klaas E. A., Rozowsky, Joel, Kaczor-Urbanowicz, Karolina Elżbieta, Chang, Justin, Balaj, Leonora, Losic, Bojan, Van Nostrand, Eric L., LaPlante, Emily, Mateescu, Bogdan, White, Brian S., Yu, Rongshan, Milosavljevic, Aleksander, Stolovitzky, Gustavo, Spengler, Ryan M.

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