Výsledky vyhledávání - Sophia Tsoka

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  1. 1
    The Phylogenetic Extent of Metabolic Enzymes and Pathways

    The Phylogenetic Extent of Metabolic Enzymes and Pathways Autor José M. Peregrín-Alvarez, Sophia Tsoka, Christos Ouzounis

    Vydáno 2003
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  2. 2
    Detection of Composite Communities in Multiplex Biological Networks

    Detection of Composite Communities in Multiplex Biological Networks Autor Laura Bennett, Aristotelis Kittas, Gareth Muirhead, Lazaros G. Papageorgiou, Sophia Tsoka

    Vydáno 2015
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  3. 3
    Genome evolution reveals biochemical networks and functional modules

    Genome evolution reveals biochemical networks and functional modules Autor Christian von Mering, Evgeny M. Zdobnov, Sophia Tsoka, Francesca D. Ciccarelli, José B. Pereira‐Leal, Christos Ouzounis, Peer Bork

    Vydáno 2003
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  4. 4
    Transcriptome classification reveals molecular subtypes in psoriasis

    Transcriptome classification reveals molecular subtypes in psoriasis Autor Chrysanthi Ainali, Najl V. Valeyev, Gayathri Perera, Andrew E. Williams, Jóhann E. Guðjónsson, Christos Ouzounis, Frank O. Nestlé, Sophia Tsoka

    Vydáno 2012
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  5. 5
    CAST: an iterative algorithm for the complexity analysis of sequence tracts

    CAST: an iterative algorithm for the complexity analysis of sequence tracts Autor Vasilis J. Promponas, Anton J. Enright, Sophia Tsoka, David P. Kreil, Christophe Leroy, Stavros J. Hamodrakas, Chris Sander, Christos Ouzounis

    Vydáno 2000
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  6. 6
    A Systems Model for Immune Cell Interactions Unravels the Mechanism of Inflammation in Human Skin

    A Systems Model for Immune Cell Interactions Unravels the Mechanism of Inflammation in Human Skin Autor Najl V. Valeyev, Christian Hundhausen, Yoshinori Umezawa, Nikolay V. Kotov, Gareth Williams, Alex Clop, Crysanthi Ainali, Christos Ouzounis, Sophia Tsoka, Frank O. Nestlé

    Vydáno 2010
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  7. 7
    Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types

    Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types Autor Kristina M. Ilieva, Anthony Cheung, Silvia Mele, Giulia Chiaruttini, Silvia Crescioli, Merope Griffin, Mano Nakamura, James Spicer, Sophia Tsoka, Katie E. Lacy, Andrew Tutt, Sophia N. Karagiannis

    Vydáno 2018
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  8. 8
    TIGIT blockade repolarizes AML-associated TIGIT<sup>+</sup>M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis

    TIGIT blockade repolarizes AML-associated TIGIT<sup>+</sup>M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis Autor Franziska Brauneck, Brit Fischer, Marius Witt, Jana Muschhammer, Jennyfer Oelrich, Pedro Avelar, Sophia Tsoka, Lars Bullinger, Elisa Seubert, Daniel J. Smit, Carsten Bokemeyer, Christin Ackermann, Jasmin Wellbrock, Friedrich Haag, Walter Fiedler

    Vydáno 2022
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  9. 9
    An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities

    An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities Autor Lais C. G. F. Palhares, Melanie Grandits, Katie Stoker, Jitesh Chauhan, Heng Sheng Sow, Gilbert O. Fruhwirth, Sophia Tsoka, James R. Birtley, Leanne Partington, T. Wilson, Elizabeth Hardaker, Sophia N. Karagiannis, Heather J. Bax, Kevin Fitzgerald

    Vydáno 2025
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  10. 10
    Enriched circulating and tumor-resident TGF-β<sup>+</sup>regulatory B cells in patients with melanoma promote FOXP3<sup>+</sup>Tregs

    Enriched circulating and tumor-resident TGF-β<sup>+</sup>regulatory B cells in patients with melanoma promote FOXP3<sup>+</sup>Tregs Autor R. J. C. Harris, Zena Willsmore, Roman Laddach, Silvia Crescioli, Jitesh Chauhan, Anthony Cheung, Anna Black, Jenny L. C. Geh, Alastair D. MacKenzie Ross, Ciaran Healy, Sophia Tsoka, James Spicer, Katie E. Lacy, Sophia N. Karagiannis

    Vydáno 2022
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  11. 11
    IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states

    IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states Autor Giulia Pellizzari, Coran Hoskin, Silvia Crescioli, Silvia Mele, Jelena Gotovina, Giulia Chiaruttini, Rodolfo Bianchini, Kristina M. Ilieva, Heather J. Bax, Sophie Papa, Katie E. Lacy, Erika Jensen‐Jarolim, Sophia Tsoka, Debra H. Josephs, James Spicer, Sophia N. Karagiannis

    Vydáno 2019
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  12. 12
    Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors

    Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors Autor Melanie Grandits, Lais C. G. F. Palhares, Gabriel Osborn, Jitesh Chauhan, Katie Stoker, Heng Sheng Sow, Rebecca Adams, Alexandra McCraw, Alicia M. Chenoweth, Sofia Vlasova, Jacobo López‐Abente, Kristina M. Ilieva, James R. Birtley, Sophia Tsoka, Elizabeth Hardaker, Kevin Fitzgerald, Sophia N. Karagiannis, Heather J. Bax

    Vydáno 2025
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  13. 13
    Anti-EGFR antibody-drug conjugate carrying an inhibitor targeting CDK restricts triple-negative breast cancer growth

    Anti-EGFR antibody-drug conjugate carrying an inhibitor targeting CDK restricts triple-negative breast cancer growth Autor Anthony Cheung, Alicia M. Chenoweth, Annelie Johansson, Roman Laddach, Naomi Guppy, Jennifer Trendell, Benjamina Esapa, Antranik Mavousian, Blanca Navarro‐Llinas, Syed Haider, Pablo Romero-Clavijo, Ricarda M. Hoffmann, Paolo Andriollo, Khondaker Miraz Rahman, Paul Jackson, Sophia Tsoka, Sheeba Irshad, Ioannis Roxanis, Anita Grigoriadis, David E. Thurston, Christopher J. Lord, Andrew Tutt, Sophia N. Karagiannis

    Vydáno 2024
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  14. 14
    B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies

    B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies Autor Zena Willsmore, R. J. C. Harris, Silvia Crescioli, Khuluud Hussein, Helen Kakkassery, Deepika Thapa, Anthony Cheung, Jitesh Chauhan, Heather J. Bax, Alicia M. Chenoweth, Roman Laddach, Gabriel Osborn, Alexa McCraw, Ricarda M. Hoffmann, Mano Nakamura, Jenny L. C. Geh, Alastair D. MacKenzie Ross, Ciaran Healy, Sophia Tsoka, James Spicer, Sophie Papa, Linda D. Barber, Katie E. Lacy, Sophia N. Karagiannis

    Vydáno 2021
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  15. 15
    Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action

    Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action Autor Zena Willsmore, Ben G T Coumbe, Silvia Crescioli, Sara Reci, Ayushi Gupta, R. J. C. Harris, Alicia M. Chenoweth, Jitesh Chauhan, Heather J. Bax, Alexa McCraw, Anthony Cheung, Gabriel Osborn, Ricarda M. Hoffmann, Mano Nakamura, Roman Laddach, Jenny L. C. Geh, Alastair D. MacKenzie Ross, Ciaran Healy, Sophia Tsoka, James Spicer, Debra H. Josephs, Sophie Papa, Katie E. Lacy, Sophia N. Karagiannis

    Vydáno 2021
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  16. 16
    Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer

    Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer Autor R. J. C. Harris, Anthony Cheung, Joseph Ng, Roman Laddach, Alicia M. Chenoweth, Silvia Crescioli, Matthew W. Fittall, Diana Dominguez-Rodriguez, J.T. Roberts, Dina Levi, Fangfang Liu, Elena Alberts, Jelmar Quist, Aida Santaolalla, Sarah E. Pinder, Cheryl Gillett, Niklas Hammar, Sheeba Irshad, Mieke Van Hemelrijck, Deborah K. Dunn‐Walters, Franca Fraternali, James Spicer, Katie E. Lacy, Sophia Tsoka, Anita Grigoriadis, Andrew Tutt, Sophia N. Karagiannis

    Vydáno 2021
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  17. 17
    Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction

    Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction Autor Gabriel Osborn, Jacobo López‐Abente, Rebecca Adams, Roman Laddach, Melanie Grandits, Heather J. Bax, Jitesh Chauhan, Giulia Pellizzari, Mano Nakamura, Chara Stavraka, Alicia M. Chenoweth, Lais C. G. F. Palhares, Theodore Evan, Jamie Lim, Amanda L. Gross, Leonard Moise, Shashidhar S. Jatiani, Mariangela Figini, Rodolfo Bianchini, Erika Jensen‐Jarolim, Sharmistha Ghosh, Ana Montes, Ahmad Sayasneh, Rebecca Kristeleit, Sophia Tsoka, James Spicer, Debra H. Josephs, Sophia N. Karagiannis

    Vydáno 2025
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  18. 18
    Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes

    Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes Autor Heather J. Bax, Jitesh Chauhan, Chara Stavraka, Aida Santaolalla, Gabriel Osborn, Atousa Khiabany, Melanie Grandits, Jacobo López‐Abente, Lais C. G. F. Palhares, Charleen Chan Wah Hak, Alexandra Robinson, Amy Pope, Natalie Woodman, Cristina Naceur‐Lombardelli, Sadek Malas, Jack Coumbe, Mano Nakamura, Roman Laddach, Silvia Mele, Silvia Crescioli, Anna M. Black, Sara Lombardi, Silvana Canevari, Mariangela Figini, Ahmad Sayasneh, Sophia Tsoka, Kevin T. Fitzgerald, Cheryl Gillett, Sarah E. Pinder, Mieke Van Hemelrijck, Rebecca Kristeleit, Sharmistha Ghosh, Ana Montes, James Spicer, Sophia N. Karagiannis, Debra H. Josephs

    Vydáno 2022
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  19. 19
    Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling

    Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling Autor Debra H. Josephs, Heather J. Bax, Tihomir Dodev, Mirella Georgouli, Mano Nakamura, Giulia Pellizzari, Louise Saul, Panagiotis Karagiannis, Anthony Cheung, Cecilia Herráiz, Kristina M. Ilieva, Isabel Corrêa, Matthew W. Fittall, Silvia Crescioli, Patrycja Gazińska, Natalie Woodman, Silvia Mele, Giulia Chiaruttini, Amy E. Gilbert, Alexander Koers, Marguerite Bracher, Christopher Selkirk, Heike Lentfer, Claire Barton, Elliott Lever, Gareth Muirhead, Sophia Tsoka, Silvana Canevari, Mariangela Figini, Ana Montes, Noel Downes, David Dombrowicz, Christopher J. Corrigan, Andrew J. Beavil, Frank O. Nestlé, Paul S. Jones, Hannah J. Gould, Victoria Sanz‐Moreno, Philip J. Blower, James Spicer, Sophia N. Karagiannis

    Vydáno 2017
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  20. 20
    Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis

    Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis Autor Óscar Maiques, Marta C. Sallán, Roman Laddach, Pahini Pandya, A. Senra Varela, Eva Crosas‐Molist, Jaume Barcelo, Olivia Courbot, Yanbo Liu, Vittoria Graziani, Youssef Arafat, J.I. Sewell, Irene Rodríguez‐Hernández, Bruce Fanshawe, Yaiza Jung-Garcia, Paul R. C. Imbert, Eloïse M. Grasset, Jean Albrengues, Marı́a Santacana, Anna Macià, Jordi Tarragona, Xavier Matías‐Guiu, Manuel Martín González, Sophia Tsoka, Cédric Gaggioli, José L. Orgaz, Gilbert O. Fruhwirth, Fredrik Wållberg, Kai Betteridge, Constantino Carlos Reyes‐Aldasoro, Syed Haider, Andrejs Braun, Sophia N. Karagiannis, Alberto Elósegui-Artola, Victoria Sanz‐Moreno

    Vydáno 2025
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