Suchergebnisse - Sonya Zabludoff

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  1. 1
    DNA Damage Detection and Repair Pathways—Recent Advances with Inhibitors of Checkpoint Kinases in Cancer Therapy

    DNA Damage Detection and Repair Pathways—Recent Advances with Inhibitors of Checkpoint Kinases in Cancer Therapy von Susan Ashwell, Sonya Zabludoff

    Veröffentlicht 2008
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  2. 2
    Cyclic Protein-2, a Secretory Product of Rat Sertoli Cells, is the Proenzyme Form of Cathepsin L

    Cyclic Protein-2, a Secretory Product of Rat Sertoli Cells, is the Proenzyme Form of Cathepsin L von Moira Erickson-Lawrence, Sonya Zabludoff, William W. Wright

    Veröffentlicht 1991
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  3. 3
    Histone Deacetylase Inhibition Selectively Alters the Activity and Expression of Cell Cycle Proteins Leading to Specific Chromatin Acetylation and Antiproliferative Effects

    Histone Deacetylase Inhibition Selectively Alters the Activity and Expression of Cell Cycle Proteins Leading to Specific Chromatin Acetylation and Antiproliferative Effects von Lidia Sambucetti, Denise Fischer, Sonya Zabludoff, Paul Kwon, H Chamberlin, Nancy Trogani, Hong Xu, Dalia Cohen

    Veröffentlicht 1999
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  4. 4
    Chk1 inhibition after replicative stress activates a double strand break response mediated by ATM and DNA-dependent protein kinase

    Chk1 inhibition after replicative stress activates a double strand break response mediated by ATM and DNA-dependent protein kinase von Samuel McNeely, Chiara Conti, Tahir Sheikh, Himali Patel, Sonya Zabludoff, Yves Pommier, Gary K. Schwartz, Archie Tse

    Veröffentlicht 2010
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  5. 5
    <i>In vitro</i> and <i>In vivo</i> Radiation Sensitization of Human Tumor Cells by a Novel Checkpoint Kinase Inhibitor, AZD7762

    <i>In vitro</i> and <i>In vivo</i> Radiation Sensitization of Human Tumor Cells by a Novel Checkpoint Kinase Inhibitor, AZD7762 von James B. Mitchell, Rajani Choudhuri, Kristin Fabre, Anastasia L. Sowers, Deborah E. Citrin, Sonya Zabludoff, John A. Cook

    Veröffentlicht 2010
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  6. 6
    Sensitization of Pancreatic Cancer Stem Cells to Gemcitabine by Chk1 Inhibition

    Sensitization of Pancreatic Cancer Stem Cells to Gemcitabine by Chk1 Inhibition von Venkatasubbaiah A. Venkatesha, Leslie A. Parsels, Joshua D. Parsels, Lili Zhao, Sonya Zabludoff, Diane M. Simeone, Jonathan Maybaum, Theodore S. Lawrence, Meredith A. Morgan

    Veröffentlicht 2012
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  7. 7
    miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells

    miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells von Jing Zhang, Jingjing Jiao, Silvia Cermelli, Kyle Muir, Kwang Hwa Jung, Ruhai Zou, Asif Rashid, Mihai Gagea, Sonya Zabludoff, Raghu Kalluri, Laura Beretta

    Veröffentlicht 2015
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  8. 8
    Anti-<i>miR182</i> Reduces Ovarian Cancer Burden, Invasion, and Metastasis: An <i>In Vivo</i> Study in Orthotopic Xenografts of Nude Mice

    Anti-<i>miR182</i> Reduces Ovarian Cancer Burden, Invasion, and Metastasis: An <i>In Vivo</i> Study in Orthotopic Xenografts of Nude Mice von Xiaofei Xu, Bushra Ayub, Zhaojian Liu, Vanida A. Serna, Wenan Qiang, Yugang Liu, Eva Hernando, Sonya Zabludoff, Takeshi Kurita, Beihua Kong, Jian-Jun Wei

    Veröffentlicht 2014
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  9. 9
    Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors

    Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors von Edward A. Sausville, Patricia LoRusso, Michael A. Carducci, Judith Carter, Mary Flanagan Quinn, Lisa Malburg, Nilofer S. Azad, David Cosgrove, Richard Knight, Peter Barker, Sonya Zabludoff, Felix Agbo, Patricia Oakes, Adrian M. Senderowicz

    Veröffentlicht 2014
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  10. 10
    Mechanism of Radiosensitization by the Chk1/2 Inhibitor AZD7762 Involves Abrogation of the G2 Checkpoint and Inhibition of Homologous Recombinational DNA Repair

    Mechanism of Radiosensitization by the Chk1/2 Inhibitor AZD7762 Involves Abrogation of the G2 Checkpoint and Inhibition of Homologous Recombinational DNA Repair von Meredith A. Morgan, Leslie A. Parsels, Lili Zhao, Joshua D. Parsels, Mary A. Davis, Maria Hassan, Sankari Arumugarajah, Linda Hylander-Gans, Deborah Morosini, Diane M. Simeone, Christine E. Canman, Daniel P. Normolle, Sonya Zabludoff, Jonathan Maybaum, Theodore S. Lawrence

    Veröffentlicht 2010
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  11. 11
    Assessment of Chk1 Phosphorylation as a Pharmacodynamic Biomarker of Chk1 Inhibition

    Assessment of Chk1 Phosphorylation as a Pharmacodynamic Biomarker of Chk1 Inhibition von Leslie A. Parsels, Yushen Qian, Daria M. Tanska, Marisa Gross, Lili Zhao, Maria Hassan, Sankari Arumugarajah, Joshua D. Parsels, Linda Hylander-Gans, Diane M. Simeone, Deborah Morosini, Jeffrey L. Brown, Sonya Zabludoff, Jonathan Maybaum, Theodore S. Lawrence, Meredith A. Morgan

    Veröffentlicht 2011
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  12. 12
    Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

    Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway von Andrew L. Kung, Sonya Zabludoff, Dennis S. France, Steven J. Freedman, E Tanner, Annelisa Vieira, Susan Cornell-Kennon, Jennifer Lee, Beqing Wang, Jamin Wang, Klaus Memmert, Hans‐Ulrich Naegeli, Frank Petersen, Michael J. Eck, Kenneth W. Bair, Alexander W. Wood, David M. Livingston

    Veröffentlicht 2004
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  13. 13
    Proteomics-based Target Identification

    Proteomics-based Target Identification von Harry Towbin, Kenneth W. Bair, James A. DeCaprio, Michael J. Eck, Sunkyu Kim, Frederick R. Kinder, Anthony A. Morollo, Dieter Mueller, Patrick Schindler, Hyun Kyu Song, Jan van Oostrum, Richard Versace, Hans Voshol, Jeanette M. Wood, Sonya Zabludoff, Penny E. Phillips

    Veröffentlicht 2003
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  14. 14
    AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies

    AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies von Sonya Zabludoff, Chun Deng, Michael Grondine, Adam Sheehy, Susan Ashwell, Benjamin Caleb, Stephen Green, Heather Haye, Candice L. Horn, James W. Janetka, Dongfang Liu, Elizabeth Mouchet, Shannon Ready, Judith L. Rosenthal, Christophe Quéva, Gary K. Schwartz, Karen J. Taylor, Archie Tse, Graeme E. Walker, Anne M. White

    Veröffentlicht 2008
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  15. 15
    Identification of the endosomal sorting complex required for transport-I (ESCRT-I) as an important modulator of anti-miR uptake by cancer cells

    Identification of the endosomal sorting complex required for transport-I (ESCRT-I) as an important modulator of anti-miR uptake by cancer cells von Timothy R. Wagenaar, Tatiana Tolstykh, Chaomei Shi, Lan Jiang, JingXin Zhang, Zhifang Li, Qunyan Yu, Hui Qu, Fangxian Sun, Hui Cao, Jack Pollard, Shujia Dai, Qiang Gao, Bailin Zhang, Heike Arlt, May Cindhuchao, Dietmar Hoffmann, Madelyn Light, Karin Jensen, Joern Hopke, Richard Newcombe, Carlos Garcı́a-Echeverrı́a, Christopher Winter, Sonya Zabludoff, Dmitri Wiederschain

    Veröffentlicht 2014
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  16. 16
    Anti–miR-21 Suppresses Hepatocellular Carcinoma Growth via Broad Transcriptional Network Deregulation

    Anti–miR-21 Suppresses Hepatocellular Carcinoma Growth via Broad Transcriptional Network Deregulation von Timothy R. Wagenaar, Sonya Zabludoff, Sung‐Min Ahn, Charles Allerson, Heike Arlt, Raffaele Baffa, Hui Cao, Scott Davis, Carlos Garcı́a-Echeverrı́a, Rajula Gaur, Shih-Min A. Huang, Lan Jiang, Deokhoon Kim, Christiane Metz-Weidmann, Adam Pavlı́ček, Jack Pollard, Jason Reeves, Jennifer L. Rocnik, Sabine Scheidler, Chaomei Shi, Fangxian Sun, Tatiana Tolstykh, William Weber, Christopher Winter, Eunsil Yu, Qunyan Yu, Gang Zheng, Dmitri Wiederschain

    Veröffentlicht 2015
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