Suchergebnisse - Sonja Hager

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  1. 1
    Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling

    Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling von Zhengnan Cai, Li Wan, Sonja Hager, Jayne Louise Wilson, Leila Afjehi-Sadat, Elke H. Heiß, Thomas Weichhart, Petra Heffeter, Wolfram Weckwerth

    Veröffentlicht 2024
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  2. 2
    Biological activity of PtIV prodrugs triggered by riboflavin-mediated bioorthogonal photocatalysis

    Biological activity of PtIV prodrugs triggered by riboflavin-mediated bioorthogonal photocatalysis von Silvia Alonso‐de Castro, Alessio Terenzi, Sonja Hager, Bernhard Englinger, Adriana Faraone, Javier Calvo, M. Galanski, Bernhard K. Keppler, Walter Berger, Luca Salassa

    Veröffentlicht 2018
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  3. 3
    Impact of Stepwise NH<sub>2</sub>-Methylation of Triapine on the Physicochemical Properties, Anticancer Activity, and Resistance Circumvention

    Impact of Stepwise NH<sub>2</sub>-Methylation of Triapine on the Physicochemical Properties, Anticancer Activity, and Resistance Circumvention von Christian R. Kowol, Walter Miklos, Sarah Pfaff, Sonja Hager, Sebastian Kallus, Karla Pelivan, Mario Kubanik, Éva A. Enyedy, Walter Berger, Petra Heffeter, Bernhard K. Keppler

    Veröffentlicht 2016
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  4. 4
    Copper-Catalyzed Glutathione Oxidation is Accelerated by the Anticancer Thiosemicarbazone Dp44mT and Further Boosted at Lower pH

    Copper-Catalyzed Glutathione Oxidation is Accelerated by the Anticancer Thiosemicarbazone Dp44mT and Further Boosted at Lower pH von Enrico Falcone, Alessandra Gilda Ritacca, Sonja Hager, Hemma Schueffl, Bertrand Vileno, Youssef El Khoury, Petra Hellwig, Christian R. Kowol, Petra Heffeter, Emilia Sicilia, Peter Faller

    Veröffentlicht 2022
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  5. 5
    Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1

    Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC... von Maria Laura Pati, Diana Groza, Chiara Riganti, Joanna Kopecka, Mauro Niso, Francesco Berardi, Sonja Hager, Petra Heffeter, Miwa Hirai, Hitoshi Tsugawa, Yasuaki Kabe, Makoto Suematsu, Carmen Abate

    Veröffentlicht 2016
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  6. 6
    Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux

    Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Eff... von Julia H. Bormio Nunes, Sonja Hager, Marlene Mathuber, Vivien Pósa, Alexander Roller, Éva A. Enyedy, Alessia Stefanelli, Walter Berger, Bernhard K. Keppler, Petra Heffeter, Christian R. Kowol

    Veröffentlicht 2020
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  7. 7
    High Copper Complex Stability and Slow Reduction Kinetics as Key Parameters for Improved Activity, Paraptosis Induction, and Impact on Drug-Resistant Cells of Anticancer Thiosemicarbazones

    High Copper Complex Stability and Slow Reduction Kinetics as Key Parameters for Improved Activity, Paraptosis Induction, and Impact on Drug-Resistant Cells of Anticancer Thiosemica... von Sonja Hager, Veronika F.S. Pape, Vivien Pósa, Bianca Montsch, Lukas Uhlik, Gergely Szakács, Szilárd Tóth, Nikolett Jabronka, Bernhard K. Keppler, Christian R. Kowol, Éva A. Enyedy, Petra Heffeter

    Veröffentlicht 2020
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  8. 8
    Thiosemicarbazone Derivatives Developed to Overcome COTI-2 Resistance

    Thiosemicarbazone Derivatives Developed to Overcome COTI-2 Resistance von Vivien Pósa, Alessia Stefanelli, Julia H. Bormio Nunes, Sonja Hager, Marlene Mathuber, Nóra V. May, Walter Berger, Bernhard K. Keppler, Christian R. Kowol, Éva A. Enyedy, Petra Heffeter

    Veröffentlicht 2022
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  9. 9
    Structure–Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands

    Structure–Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands von Philipp Fronik, Isabella Poetsch, Alexander Kastner, Theresa Mendrina, Sonja Hager, Katharina Hohenwallner, Hemma Schueffl, Dietmar Herndler‐Brandstetter, Gunda Koellensperger, Evelyn Rampler, Joanna Kopecka, Chiara Riganti, Walter Berger, Bernhard K. Keppler, Petra Heffeter, Christian R. Kowol

    Veröffentlicht 2021
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  10. 10
    The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

    The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition von Sonja Hager, Katharina Korbula, Bjoern Bielec, Michael Grusch, Christine Pirker, Markus Schosserer, Lisa Liendl, Magdalena Lang, Johannes Grillari, Karin Nowikovsky, Veronika F.S. Pape, Thomas Mohr, Gergely Szakács, Bernhard K. Keppler, Walter Berger, Christian R. Kowol, Petra Heffeter

    Veröffentlicht 2018
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  11. 11
    FGF2 and EGF induce epithelial–mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal

    FGF2 and EGF induce epithelial–mesenchymal transition in malignant pleural mesothelioma cells via a MAPKinase/MMP1 signal von Karin Schelch, Christina Wagner, Sonja Hager, Christine Pirker, Katharina M. Siess, Elisabeth Lang, Ruby C.Y. Lin, Michaela B. Kirschner, Thomas Mohr, Luka Brčić, Brigitte Marian, Klaus Holzmann, Bettina Grasl‐Kraupp, Georg Krupitza, Viktória László, Thomas Klikovits, Balázs Döme, Balázs Hegedűs, Tamás Garay, Glen Reid, Nico van Zandwijk, Walter Klepetko, Walter Berger, Michael Grusch, Mir Alireza Hoda

    Veröffentlicht 2018
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