نتائج البحث - Sonia M. Vallabh

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  1. 1
    Characterization of the Prion Protein Binding Properties of Antisense Oligonucleotides

    Characterization of the Prion Protein Binding Properties of Antisense Oligonucleotides حسب Andrew G. Reidenbach, Eric Vallabh Minikel, Hien Zhao, Stacy Guzman, Alison Leed, Michael F. Mesleh, Holly Kordasiewicz, Stuart L. Schreiber, Sonia M. Vallabh

    منشور في 2019
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  2. 2
    A single-cell map of antisense oligonucleotide activity in the brain

    A single-cell map of antisense oligonucleotide activity in the brain حسب Meredith A Mortberg, Juliana E Gentile, Naeem Nadaf, Charles Vanderburg, Sean Simmons, Dan Dubinsky, Adam Slamin, Salome Maldonado, Caroline L Petersen, Nichole Jones, Holly Kordasiewicz, Hien Zhao, Sonia M. Vallabh, Eric Vallabh Minikel

    منشور في 2023
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  3. 3
    Novel quaternary structures of the human prion protein globular domain

    Novel quaternary structures of the human prion protein globular domain حسب Leandro Oliveira Bortot, V.L. Rangel, Francesca A. Pavlovici, Kamel El Omari, Armin Wagner, J. Brandão-Neto, R. Talon, F. von Delft, Andrew G. Reidenbach, Sonia M. Vallabh, Eric Vallabh Minikel, Stuart L. Schreiber, Maria Cristina Nonato

    منشور في 2021
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  4. 4
    Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development

    Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development حسب Sonia M. Vallabh, Chloe K. Nobuhara, Franc Llorens, Inga Zerr, Piero Parchi, Sabina Capellari, Eric Kuhn, Jacob A. Klickstein, Jiri Safar, Flávia C. Nery, Kathryn J. Swoboda, Michael D. Geschwind, Henrik Zetterberg, Steven E. Arnold, Eric Vallabh Minikel, Stuart L. Schreiber

    منشور في 2019
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  5. 5
    Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation

    Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation حسب Marta Biagioli, Francesco Ferrari, Eric M. Mendenhall, Yijing Zhang, Serkan Erdin, Ravi Vijayvargia, Sonia M. Vallabh, Nicole Solomos, Poornima Manavalan, Ashok Ragavendran, Fatih Ozsolak, Jong Min Lee, Michael E. Talkowski, James F. Gusella, Marcy E. MacDonald, Peter J. Park, Ihn Sik Seong

    منشور في 2015
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  6. 6
    Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease

    Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease حسب Sonia M. Vallabh, Eric Vallabh Minikel, Victoria J. Williams, Becky C. Carlyle, Alison J. McManus, Chase Wennick, Anna Bolling, Bianca A. Trombetta, David Urick, Chloe K. Nobuhara, Jessica Gerber, Holly Duddy, Ingolf Lachmann, Christiane Stehmann, Steven Collins, Kaj Blennow, Henrik Zetterberg, Steven E. Arnold

    منشور في 2020
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  7. 7
    Antisense oligonucleotides extend survival of prion-infected mice

    Antisense oligonucleotides extend survival of prion-infected mice حسب Gregory J. Raymond, Hien Zhao, Brent Race, Lynne D. Raymond, Katie Williams, Eric E. Swayze, Samantha Graffam, Jason Le, Tyler Caron, Jacquelyn Stathopoulos, Rhonda O’Keefe, Lori Lubke, Andrew G. Reidenbach, Allison Kraus, Stuart L. Schreiber, Curt Mazur, Deborah E. Cabin, Jeffrey B. Carroll, Eric Vallabh Minikel, Holly Kordasiewicz, Byron Caughey, Sonia M. Vallabh

    منشور في 2019
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  8. 8
    Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints

    Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints حسب Eric Vallabh Minikel, Hien Zhao, Jason Le, Jill O’Moore, Rose Pitstick, Samantha Graffam, George A. Carlson, Michael P. Kavanaugh, Jasna Križ, Jae Beom Kim, Jiyan Ma, Holger Wille, Judd M. Aiken, Deborah McKenzie, Katsumi Doh‐ura, Matthew V. Beck, Rhonda O’Keefe, Jacquelyn Stathopoulos, Tyler Caron, Stuart L. Schreiber, Jeffrey B. Carroll, Holly Kordasiewicz, Deborah E. Cabin, Sonia M. Vallabh

    منشور في 2020
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  9. 9
    Evidence that minocycline treatment confounds the interpretation of neurofilament as a biomarker

    Evidence that minocycline treatment confounds the interpretation of neurofilament as a biomarker حسب Juliana E Gentile, Christina N. Heiss, Taylor L Corridon, Meredith A Mortberg, Stefanie Fruhwürth, Kenia Guzman, Lana Grötschel, Laia Montoliu‐Gaya, Kwan L. Chan, Neil Herring, Timothy Janicki, Rajaa Nhass, Janani Manavala Sarathy, Brian K. Erickson, Ryan C. Kunz, Alison R. Erickson, Craig R. Braun, Katherine T Henry, Lynn Bry, Steven E. Arnold, Eric Vallabh Minikel, Henrik Zetterberg, Sonia M. Vallabh

    منشور في 2025
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  10. 10
    Multimodal small-molecule screening for human prion protein binders

    Multimodal small-molecule screening for human prion protein binders حسب Andrew G. Reidenbach, Michael F. Mesleh, Dominick Casalena, Sonia M. Vallabh, Jayme L. Dahlin, Alison Leed, Alix I Chan, Dmitry L. Usanov, Jenna Yehl, Christopher T. Lemke, Arthur J. Campbell, Rishi Shah, Om Kumar Shrestha, Joshua R. Sacher, V.L. Rangel, Jamie A. Moroco, Murugappan Sathappa, Maria Cristina Nonato, Kong T. Nguyen, S. Kirk Wright, David R. Liu, Florence F. Wagner, Virendar K. Kaushik, Douglas S. Auld, Stuart L. Schreiber, Eric Vallabh Minikel

    منشور في 2020
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  11. 11
    Multimodal small-molecule screening for human prion protein binders

    Multimodal small-molecule screening for human prion protein binders حسب Andrew G. Reidenbach, Michael F. Mesleh, Dominick Casalena, Sonia M. Vallabh, Jayme L. Dahlin, Alison Leed, Alix I Chan, Dmitry L. Usanov, Jenna Yehl, Christopher T. Lemke, Arthur J. Campbell, Rishi Shah, Om Kumar Shrestha, Joshua R. Sacher, V.L. Rangel, Jamie A. Moroco, Murugappan Sathappa, Maria Cristina Nonato, Kong T. Nguyen, S. Kirk Wright, David R. Liu, Florence F. Wagner, Virendar K. Kaushik, Douglas S. Auld, Stuart L. Schreiber, Eric Vallabh Minikel

    منشور في 2020
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  12. 12
    In vivo base editing extends lifespan of a humanized mouse model of prion disease

    In vivo base editing extends lifespan of a humanized mouse model of prion disease حسب Meirui An, Jessie R. Davis, Jonathan M. Levy, Fiona E. Serack, John Harvey, Pamela P. Brauer, Catherine P. Pirtle, Kiara N. Berríos, Gregory A. Newby, Wei-Hsi Yeh, N. Kamath, Meredith A Mortberg, Yuan Lian, Michael S. Howard, Kendrick DeSouza-Lenz, Kenia Guzman, A. C. Thai, Samantha Graffam, Alissa A. Coffey, J Frei, Sarah E. Pierce, Jiri Safar, Benjamin E. Deverman, Eric Vallabh Minikel, Sonia M. Vallabh, David R. Liu

    منشور في 2025
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  13. 13
    Age at onset in genetic prion disease and the design of preventive clinical trials

    Age at onset in genetic prion disease and the design of preventive clinical trials حسب Eric Vallabh Minikel, Sonia M. Vallabh, Margaret C. Orseth, Jean‐Philippe Brandel, Stéphane Haı̈k, Jean Laplanche, Inga Zerr, Piero Parchi, Sabina Capellari, Jiri Safar, Joanna Kenny, Jamie Fong, Leonel Tadao Takada, Claudia Ponto, Péter Hermann, Tobias Knipper, Christiane Stehmann, Tetsuyuki Kitamoto, Ryusuke Ae, Tsuyoshi Hamaguchi, Nobuo Sanjo, Tadashi Tsukamoto, Hidehiro Mizusawa, Steven Collins, Roberto Chiesa, Ignazio Roiter, Jesús de Pedro‐Cuesta, Miguel Calero, Michael D. Geschwind, Masahito Yamada, Yosikazu Nakamura, Simon Mead

    منشور في 2019
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  14. 14
    Zinc Finger Repressors mediate widespread PRNP lowering in the nonhuman primate brain and profoundly extend survival in prion disease mice

    Zinc Finger Repressors mediate widespread PRNP lowering in the nonhuman primate brain and profoundly extend survival in prion disease mice حسب Shih‐Wei Chou, Meredith A Mortberg, Kimberly Marlen, David S. Ojala, Toufan Parman, Michael W. Howard, Kendrick DeSouza-Lenz, Yuan Lian, Mohadeseh Mehrabian, Matthew Tiffany, Annemarie Ledeboer, Patrick Dunn, Jing Hu, Kenia Guzman, N. Kamath, M. H. Cass, Samantha Graffam, Li Xu, Vanessa Laversenne, Taylor L Corridon, Alaric Falcon, Garrett Lew, Satria P. Sajuthi, Lei Zhang, Giulia Cisbani, Finn Peters, Tim Fieblinger, Chiara Melis, Janica Barenberg, Marharyta Hnatiuk, Yu Qi, Daniel W. Chung, Mihika Jalan, Sarah J. Hinkley, Yanmei Lu, Kathleen Meyer, Alissa A. Coffey, Amy M. Pooler, Sonia M. Vallabh, Eric Vallabh Minikel, Bryan Zeitler

    منشور في 2025
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  15. 15
    Quantifying prion disease penetrance using large population control cohorts

    Quantifying prion disease penetrance using large population control cohorts حسب Eric Vallabh Minikel, Sonia M. Vallabh, Monkol Lek, Karol Estrada, Kaitlin E. Samocha, J. Fah Sathirapongsasuti, Cory Y. McLean, Joyce Y. Tung, Linda P. C. Yu, Pierluigi Gambetti, Janis Blevins, Shulin Zhang, Yvonne Cohen, Wei Chen, Masahito Yamada, Tsuyoshi Hamaguchi, Nobuo Sanjo, Hidehiro Mizusawa, Yosikazu Nakamura, Tetsuyuki Kitamoto, Steven Collins, Alison Boyd, Robert Will, Richard Knight, Claudia Ponto, Inga Zerr, Theo F. J. Kraus, Sabina Eigenbrod, Armin Giese, Miguel Calero, Jesús de Pedro‐Cuesta, Stéphane Haı̈k, Jean Laplanche, Elodie Bouaziz‐Amar, J.-P. Brandel, Sabina Capellari, Piero Parchi, Anna Poleggi, Anna Ladogana, Anne O’Donnell‐Luria, Konrad J. Karczewski, Jamie L. Marshall, Michael Boehnke, Markku Laakso, Karen L. Mohlke, Anna K. Kähler, Kimberly Chambert, Steven A. McCarroll, Patrick F. Sullivan, Christina M. Hultman, Shaun Purcell, Pamela Sklar, Sven J. van der Lee, Annemieke J.M. Rozemüller, Casper Jansen, Albert Hofman, Robert Kraaij, Jeroen van Rooij, M. Arfan Ikram, André G. Uitterlinden, Cornelia M. van Duijn, Mark J. Daly, Daniel G. MacArthur

    منشور في 2016
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