Resultats de la cerca - Simon Rushbrook

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  1. 1
    The Emerging Role of Bile Acids in the Pathogenesis of Inflammatory Bowel Disease

    The Emerging Role of Bile Acids in the Pathogenesis of Inflammatory Bowel Disease per John P. Thomas, Dezső Módos, Simon Rushbrook, Nick Powell, Tamás Korcsmáros

    Publicat 2022
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  2. 2
    Compromised lymphocytes infiltrate hepatocellular carcinoma: The role of T-regulatory cells

    Compromised lymphocytes infiltrate hepatocellular carcinoma: The role of T-regulatory cells per Esther Unitt, Simon Rushbrook, Aileen Marshall, Nathan Davies, Paul Gibbs, Lesley S. Morris, Nicholas Coleman, Graeme Alexander

    Publicat 2005
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  3. 3
    Regulatory T Cells Suppress In Vitro Proliferation of Virus-Specific CD8<sup>+</sup>T Cells during Persistent Hepatitis C Virus Infection

    Regulatory T Cells Suppress In Vitro Proliferation of Virus-Specific CD8<sup>+</sup>T Cells during Persistent Hepatitis C Virus Infection per Simon Rushbrook, Scott M. Ward, Esther Unitt, Sarah L. Vowler, Michaela Lucas, Paul Klenerman, Graeme Alexander

    Publicat 2005
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  4. 4
    Assessing brodalumab in the treatment of primary sclerosing cholangitis (SABR-PSC pilot study): protocol for a single-arm, multicentre, pilot study

    Assessing brodalumab in the treatment of primary sclerosing cholangitis (SABR-PSC pilot study): protocol for a single-arm, multicentre, pilot study per Amera Elzubeir, Juliet High, Matthew Hammond, Lee Shepstone, Martin Pond, Martine Walmsley, Palak Trivedi, Emma Culver, Guruprasad P. Aithal, Jessica Dyson, Douglas Thorburn, Leo Alexandre, Simon Rushbrook

    Publicat 2025
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  5. 5
    Intestinal Microbiome‐Macrophage Crosstalk Contributes to Cholestatic Liver Disease by Promoting Intestinal Permeability in Mice

    Intestinal Microbiome‐Macrophage Crosstalk Contributes to Cholestatic Liver Disease by Promoting Intestinal Permeability in Mice per Anna Isaacs‐Ten, Marta Echeandia, Mar Moreno‐Gonzalez, Arlaine Brion, Andrew Goldson, Mark Philo, Angela Patterson, Aimée Parker, Mikel Galduroz, David Baker, Simon Rushbrook, Falk Hildebrand, Naiara Beraza

    Publicat 2020
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  6. 6
    British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis

    British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis per Michael H. Chapman, Douglas Thorburn, Gideon M. Hirschfield, George Webster, Simon Rushbrook, Graeme Alexander, Jane Collier, Jessica Dyson, David Jones, Imran Patanwala, Collette Thain, Martine Walmsley, Stephen P. Pereira

    Publicat 2019
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  7. 7
    A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis

    A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis per Kris V. Kowdley, Raj Vuppalanchi, Cynthia Levy, Annarosa Floreani, Pietro Andreoné, Nicholas F. LaRusso, Roshan Shrestha, James F. Trotter, David Goldberg, Simon Rushbrook, Gideon M. Hirschfield, Thomas D. Schiano, Yuying Jin, Richard Pencek, Leigh MacConell, Д. А. Шапиро, Christopher L. Bowlus

    Publicat 2020
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  8. 8
    British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma

    British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma per Simon Rushbrook, Timothy J. Kendall, Yoh Zen, Raneem Albazaz, Prakash Manoharan, Stephen P. Pereira, Richard Sturgess, Brian R Davidson, Hassan Malik, Derek Manas, Nigel Heaton, Rajendra Prasad, John Bridgewater, Juan W. Valle, Rebecca Goody, M. Hawkins, Wendy Prentice, Helen Morement, Martine Walmsley, Shahid A. Khan

    Publicat 2023
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  9. 9
    Bacterial and metabolic phenotypes associated with inadequate response to ursodeoxycholic acid treatment in primary biliary cholangitis

    Bacterial and metabolic phenotypes associated with inadequate response to ursodeoxycholic acid treatment in primary biliary cholangitis per Laura Martinez‐Gili, Alexandros Pechlivanis, Julie A. K. McDonald, Sofina Begum, Jonathan Badrock, Jessica Dyson, Rebecca Jones, Gideon M. Hirschfield, Stephen Ryder, Richard Sandford, Simon Rushbrook, Douglas Thorburn, Simon D. Taylor‐Robinson, Mary M.E. Crossey, Julian R. Marchesi, George Mells, Elaine Holmes, David Jones

    Publicat 2023
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  10. 10
    The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS‐9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis

    The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS‐9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis per Michael Trauner, Aliya Gulamhusein, Bilal Hameed, Stephen H. Caldwell, Mitchell L. Shiffman, Charles Landis, Bertus Eksteen, Kosh Agarwal, Andrew J. Muir, Simon Rushbrook, Xiaomin Lu, Jun Xu, Jen‐Chieh Chuang, Andrew N. Billin, Georgia Li, Chuhan Chung, G. Mani Subramanian, Robert P. Myers, Christopher L. Bowlus, Kris V. Kowdley

    Publicat 2019
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  11. 11
    Fine‐Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease

    Fine‐Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease per Britt Blokker, Mònica Maijó, Marta Echeandia, Mikel Galduroz, Angela Patterson, Anna Ten, Mark Philo, Rebecca Schungel, Virginia Gutiérrez‐de Juan, Emina Halilbasic, Claudia Fuchs, Gwénaëlle Le Gall, Małgorzata Milkiewicz, Piotr Milkiewicz, Jesús M. Bañales, Simon Rushbrook, José M. Mato, Michael Trauner, Michael Müller, María Luz Martínez‐Chantar, Marta Varela‐Rey, Naiara Beraza

    Publicat 2018
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  12. 12
    Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System

    Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System per Elizabeth C. Goode, Allan Clark, George Mells, Brijesh Srivastava, Kelly Spiess, William Gelson, Palak Trivedi, Kate D. Lynch, Edit Castren, Mette Vesterhus, Tom H. Karlsen, Sun‐Gou Ji, Carl A. Anderson, Douglas Thorburn, Mark Hudson, Michael A. Heneghan, Mark Aldersley, Andrew Bathgate, Richard Sandford, Graeme Alexander, Roger W. Chapman, Martine Walmsley, Gideon M. Hirschfield, Simon Rushbrook

    Publicat 2018
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  13. 13
    APOBEC mutagenesis is a common process in normal human small intestine

    APOBEC mutagenesis is a common process in normal human small intestine per Yichen Wang, Philip S. Robinson, Tim H. H. Coorens, Luiza Moore, Henry Lee-Six, Ayesha Noorani, Mathijs A. Sanders, Hyunchul Jung, Riku Katainen, Robert Heuschkel, Roxanne Brunton-Sim, Robyn N. Weston, Debbie Read, Beverley Nobbs, Rebecca C. Fitzgerald, Kourosh Saeb‐Parsy, Iñigo Martincorena, Peter J. Campbell, Simon Rushbrook, Matthias Zilbauer, Simon J.A. Buczacki, Michael R. Stratton

    Publicat 2023
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  14. 14
    Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis

    Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis per Younghun Han, Jinyoung Byun, Catherine Zhu, Ryan Sun, Julia Y. Roh, Heather J. Cordell, Hyun‐Sung Lee, Vikram R. Shaw, Sung Wook Kang, Javad Razjouyan, Matthew A. Cooley, Manal M. Hassan, Katherine A. Siminovitch, Trine Folseraas, David Ellinghaus, Annika Bergquist, Simon Rushbrook, André Franke, Tom H. Karlsen, Konstantinos N. Lazaridis, Christoph Schramm, David Shapiro, Elizabeth C. Goode, Katherine A. McGlynn, Lewis R. Roberts, Christopher I. Amos

    Publicat 2023
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  15. 15
    Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells

    Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells per Philip S. Robinson, Laura E. Thomas, Federico Abascal, Hyunchul Jung, Luke M. R. Harvey, Hannah D. West, Sigurgeir Ólafsson, Bernard C. H. Lee, Tim H. H. Coorens, Henry Lee-Six, Laura Butlin, Nicola Lander, Rebekah Truscott, Mathijs A. Sanders, Stefanie V. Lensing, Simon J.A. Buczacki, Rogier ten Hoopen, Nicholas Coleman, Roxanne Brunton-Sim, Simon Rushbrook, Kourosh Saeb‐Parsy, Fiona Lalloo, Peter J. Campbell, Iñigo Martincorena, Julian R. Sampson, Michael R. Stratton

    Publicat 2022
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  16. 16
    Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

    Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease per Sun‐Gou Ji, Brian D. Juran, Sören Mucha, Trine Folseraas, Luke Jostins, Espen Melum, Natsuhiko Kumasaka, Elizabeth J. Atkinson, Erik M. Schlicht, Jimmy Z. Liu, Tejas Shah, Javier Gutierrez‐Achury, Kirsten Muri Boberg, Annika Bergquist, Séverine Vermeire, Bertus Eksteen, Peter R. Durie, Martti Färkkilâ, Tobias Müller, Christoph Schramm, Martina Sterneck, Tobias J. Weismüller, Daniel Gotthardt, David Ellinghaus, Felix Braun, Andreas Teufel, Mattias Laudes, Wolfgang Lieb, Gunnar Jacobs, Ulrich Beuers, Rinse K. Weersma, Cisca Wijmenga, Hanns‐Ulrich Marschall, Piotr Milkiewicz, Albert Parés, Kimmo Kontula, Olivier Chazouillères, Pietro Invernizzi, Elizabeth C. Goode, Kelly Spiess, Carmel Moore, Jennifer Sambrook, Willem H. Ouwehand, David J. Roberts, John Danesh, Annarosa Floreani, Aliya Gulamhusein, John E. Eaton, Stefan Schreiber, Catalina Coltescu, Christopher L. Bowlus, Velimir A. Luketic, Joseph A. Odin, Kapil Chopra, Kris V. Kowdley, Naga Chalasani, Michael P. Manns, Brijesh Srivastava, George Mells, Richard Sandford, Graeme Alexander, Daniel J. Gaffney, Roger W. Chapman, Gideon M. Hirschfield, Mariza de Andrade, Simon Rushbrook, André Franke, Tom H. Karlsen, Konstantinos N. Lazaridis, Carl A. Anderson

    Publicat 2016
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  17. 17
    Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis

    Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis per Rudi Alberts, Elisabeth M. G. de Vries, Elizabeth C. Goode, Xiaojun Jiang, Fotis Sampaziotis, Krista Rombouts, Katrin Böttcher, Trine Folseraas, Tobias J. Weismüller, Andrew L. Mason, Weiwei Wang, Graeme Alexander, Domenico Alvaro, Annika Bergquist, Niklas K. Björkström, Ulrich Beuers, Einar S. Björnsson, Kirsten Muri Boberg, Christopher L. Bowlus, Maria Consiglia Bragazzi, Marco Carbone, Olivier Chazouillères, Angela Cheung, George Ν. Dalekos, John E. Eaton, Bertus Eksteen, David Ellinghaus, Martti Färkkilâ, Eleonora A. Festen, Annarosa Floreani, I. Franceschet, Daniel Gotthardt, Gideon M. Hirschfield, Bart van Hoek, Kristian Holm, Simon Hohenester, Johannes R. Hov, Floris Imhann, Pietro Invernizzi, Brian D. Juran, Henrike Lenzen, Wolfgang Lieb, Jimmy Z. Liu, Hanns‐Ulrich Marschall, Marco Marzioni, Espen Melum, Piotr Milkiewicz, Tobias Müller, Albert Parés, Christian Rupp, Christian Rust, Richard Sandford, Christoph Schramm, Stefan Schreiber, Erik Schrumpf, Mark S. Silverberg, Brijesh Srivastava, Martina Sterneck, Andreas Teufel, Ludovic Vallier, Joanne Verheij, Arnau Vich Vila, Boudewijn de Vries, Kalliopi Zachou, Roger W. Chapman, Michael P. Manns, Massimo Pinzani, Simon Rushbrook, Konstantinos N. Lazaridis, André Franke, Carl A. Anderson, Tom H. Karlsen, Cyriel Y. Ponsioen, Rinse K. Weersma

    Publicat 2017
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  18. 18
    Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

    Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis per Jimmy Z. Liu, Johannes R. Hov, Trine Folseraas, Eva Ellinghaus, Simon Rushbrook, Nadezhda T. Doncheva, Ole A. Andreassen, Rinse K. Weersma, Tobias J. Weismüller, Bertus Eksteen, Pietro Invernizzi, Gideon M. Hirschfield, Daniel Gotthardt, Albert Parés, David Ellinghaus, Tejas Shah, Brian D. Juran, Piotr Milkiewicz, Christian Rust, Christoph Schramm, Tobias Müller, Brijesh Srivastava, George Ν. Dalekos, Markus M. Nöthen, Stefan Herms, Juliane Winkelmann, Mitja Mitrovič, Felix Braun, Cyriel Y. Ponsioen, Peter J.P. Croucher, Martina Sterneck, Andreas Teufel, Andrew L. Mason, Janna Saarela, Virpi Leppä, Ruslan Dorfman, Domenico Alvaro, Annarosa Floreani, Suna Önengüt-Gümüşcü, Stephen S. Rich, Wesley K. Thompson, Andrew J. Schork, Sigrid Næss, Ingo Thomsen, Gabriele Mayr, Inke R. König, Kristian Hveem, Isabelle Cleynen, Javier Gutierrez‐Achury, Isis Ricaño-Ponce, David A. van Heel, Einar Björnsson, Richard Sandford, Peter R. Durie, Espen Melum, Morten H. Vatn, Mark S. Silverberg, Richard H. Duerr, Leonid Padyukov, Stephan Brand, Miquel Sans, Vito Annese, Jean‐Paul Achkar, Kirsten Muri Boberg, Hanns‐Ulrich Marschall, Olivier Chazouillères, Christopher L. Bowlus, Cisca Wijmenga, Erik Schrumpf, Séverine Vermeire, Mario Albrecht, John D. Rioux, Graeme Alexander, Annika Bergquist, Judy H. Cho, Stefan Schreiber, Michael P. Manns, Martti Färkkilâ, Anders M. Dale, Roger W. Chapman, Konstantinos N. Lazaridis, André Franke, Carl A. Anderson, Tom H. Karlsen

    Publicat 2013
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  19. 19
    Systematic review of response criteria and endpoints in autoimmune hepatitis by the International Autoimmune Hepatitis Group

    Systematic review of response criteria and endpoints in autoimmune hepatitis by the International Autoimmune Hepatitis Group per Simon Pape, Romée J.A.L.M. Snijders, Tom J.G. Gevers, Oliver Chazouilleres, George Ν. Dalekos, Gideon M. Hirschfield, Marco Lenzi, Michael Trauner, Michael P. Manns, John M. Vierling, Aldo J. Montaño‐Loza, Ansgar W. Lohse, Christoph Schramm, Joost P.H. Drenth, Michael A. Heneghan, Piero Luigi Almasio, Fernando Álvarez, Raúl J. Andrade, Çiğdem Arıkan, David N. Assis, Edouard Bardou–Jacquet, Maaike Biewenga, Eduardo Luiz Rachid Cançado, Nora Cazzagon, Olivier Chazouillères, Guido Colloredo, Miriam Cuarterolo, George Ν. Dalekos, Dominique Debray, Mercedes Robles‐Díaz, Joost P.H. Drenth, Jessica Dyson, Cumali Efe, Bastian Engel, S. Ferri, R Fontana, Nikolaos Gatselis, Alessio Gerussi, Emina Halilbasic, Neil Halliday, Michael A. Heneghan, Gideon M. Hirschfield, Bart van Hoek, Marianne Hørby Jørgensen, G. Indolfini, Raffaele Iorio, Soo Jeong, D. Jones, Déirdre Kelly, Nanda Kerkar, Florence Lacaille, Craig Lammert, B. Leggett, Marco Lenzi, C. Levy, Rodrigo Liberal, Ana Lleó, Ansgar W. Lohse, Susana López, Eléonora De Martin, Valérie A. McLin, Giorgina Mieli‐Vergani, Piotr Milkiewicz, Nitesh Mohan, Luigi Muratori, Gabriella Nebbia, C. van Nieuwkerk, Ye Htun Oo, Alberto Ortega, Albert Parés, Tudor Lucian Pop, Daniel S. Pratt, Tuğrul Pürnak, Giusy Ranucci, Simon Rushbrook, Christoph Schramm, Albert Friedrich Stättermayer, Mark G. Swain, Atsushi Tanaka, Richard Taubert, Débora Raquel Benedita Terrabuio, Benedetta Terziroli Beretta‐Piccoli, Michael Trauner, Pamela L. Valentino, F. van den Brand, A. Villamil, Staffan Wåhlin, Henriette Ytting, Kalliopi Zachou, Mikio Zeniya

    Publicat 2022
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  20. 20
    Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls

    Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls per Carla Fiorella Murillo Perez, Holly Fisher, Shaun Hiu, Dorcas Kareithi, Femi Adekunle, Tracy J. Mayne, Elizabeth Smoot Malecha, Erik C. Ness, Adriaan J. van der Meer, Willem J. Lammers, Palak Trivedi, Pier Maria Battezzati, Frederik Nevens, Kris V. Kowdley, Tony Bruns, Nora Cazzagon, Annarosa Floreani, Andrew L. Mason, Albert Parés, María‐Carlota Londoño, Pietro Invernizzi, Marco Carbone, Ana Lleó, Marlyn J. Mayo, George Ν. Dalekos, Nikolaos Gatselis, Douglas Thorburn, Xavier Verhelst, Aliya Gulamhusein, Harry L.A. Janssen, Rachel Smith, Steve Flack, Victoria Mulcahy, Michael Trauner, Christopher L. Bowlus, Keith D. Lindor, Christophe Corpechot, David Jones, George Mells, Gideon M. Hirschfield, James Wason, Bettina E. Hansen, Richard Sturgess, Christopher G. Healey, Anton Gunasekera, Yiannis Kallis, Gavin Wright, Thiriloganathan Mathialahan, Richard J. Evans, Jaber Gasem, David Ramanaden, Emma Ward, Mahesh Bhalme, Paul Southern, James L. Maggs, Mohamed Yousif, George Mells, Brijesh Srivastava, Matthew Foxton, Carole Collins, Yash Prasad, Francisco Porras-Perez, Tom Yapp, Minesh Patel, Roland Ede, Martyn Carte, Konrad Koss, Prayman Sattianayagam, Charles Grimley, Jude Tidbury, Dina Mansour, Matilda Beckley, Coral Hollywood, John Ramag, Harriet Gordon, Joanne Ridpath, Bob Grover, George Abouda, Ian Rees, Mark Narain, Imroz Salam, Paul Banim, Debasish Das, Helen Matthews, Faiyaz Mohammed, Rebecca Jones, Sambit Sen, G. W. G. Bird, Martin Prince, Geeta Prasad, Paul Kitchen, John Hutchinson, Prakash C. Gupta, David Jones, Amir Shah, Subrata Saha, Katharine Pollock, Stephen Barclay, Natasha McDonald, Simon Rushbrook

    Publicat 2022
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