Search Results - Sihan Wu

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  1. 1
    Extrachromosomal DNA: An Emerging Hallmark in Human Cancer

    Extrachromosomal DNA: An Emerging Hallmark in Human Cancer by Sihan Wu, Vineet Bafna, Howard Y. Chang, Paul S. Mischel

    Published 2021
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  2. 2
    Modern biology of extrachromosomal DNA: A decade-long voyage of discovery

    Modern biology of extrachromosomal DNA: A decade-long voyage of discovery by Qinglin Yang, Yulei Xie, Kailiang Qiao, Jun Yi Stanley Lim, Sihan Wu

    Published 2025
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  3. 3
    Prognostic models of immune-related cell death and stress unveil mechanisms driving macrophage phenotypic evolution in colorectal cancer

    Prognostic models of immune-related cell death and stress unveil mechanisms driving macrophage phenotypic evolution in colorectal cancer by Hao Liu, Chuhan Zhang, Sanfei Peng, Yuhan Yin, Yishi Xu, Sihan Wu, Liping Wang, Yang Fu

    Published 2025
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  4. 4
    Mucosal-associated invariant T cells promote ductular reaction through amphiregulin in biliary atresia

    Mucosal-associated invariant T cells promote ductular reaction through amphiregulin in biliary atresia by Man-Huan Xiao, Sihan Wu, Peishi Liang, Dong Ma, Jiang Zhang, Huadong Chen, Zhihai Zhong, Juncheng Liu, Hong Jiang, Xuyang Feng, Zhenhua Luo

    Published 2024
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  5. 5
    Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells

    Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells by Minfeng Shu, Xiaoke Zheng, Sihan Wu, Huimin Lu, Tiandong Leng, Wenbo Zhu, Yuehan Zhou, Yanqiu Ou, Xi Lin, Yuan Lin, Dong Xu, Yuxi Zhou, Guangmei Yan

    Published 2011
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  6. 6
    PRMT3 drives PD-L1-mediated immune escape through activating PDHK1-regulated glycolysis in hepatocellular carcinoma

    PRMT3 drives PD-L1-mediated immune escape through activating PDHK1-regulated glycolysis in hepatocellular carcinoma by Chen‐Hong Ding, Fang‐Zhi Yan, Binghe Xu, Hui Qian, Xialu Hong, Shuqing Liu, Yuanyuan Luo, Sihan Wu, Ling-Yan Cai, Xin Zhang, Wei‐Fen Xie

    Published 2025
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  7. 7
    Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation

    Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation by Poshen B. Chen, Patrick Fiaux, Kai Zhang, Bin Li, Naoki Kubo, Shan Jiang, Rong Hu, Emma Rooholfada, Sihan Wu, Mengchi Wang, Wei Wang, Graham McVicker, Paul S. Mischel, Bing Ren

    Published 2022
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  8. 8
    The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24

    The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24 by Wai Po Chong, Mary J. Mattapallil, Kumarkrishna Raychaudhuri, So Jin Bing, Sihan Wu, Yajie Zhong, Weiwei Wang, Zilin Chen, Phyllis B. Silver, Yingyos Jittayasothorn, Chi‐Chao Chan, Jun Chen, Reiko Horai, Rachel R Caspi

    Published 2020
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  9. 9
    Multiplexed Nanomaterial-Based Sensor Array for Detection of COVID-19 in Exhaled Breath

    Multiplexed Nanomaterial-Based Sensor Array for Detection of COVID-19 in Exhaled Breath by Benjie Shan, Yoav Y. Broza, Wenjuan Li, Yong Wang, Sihan Wu, Zhengzheng Liu, Jiong Wang, Shuyu Gui, Lin Wang, Zhihong Zhang, Wei Liu, Shoubing Zhou, Wei Jin, Qianyu Zhang, Dandan Hu, Lin Lin, Qiujun Zhang, Wenyu Li, Jinquan Wang, Hu Liu, Yueyin Pan, Hossam Haick

    Published 2020
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  10. 10
    Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers

    Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers by Yuan Lin, Haipeng Zhang, Jiankai Liang, Kai Li, Wenbo Zhu, Liwu Fu, Fang Wang, Xiaoke Zheng, Huijuan Shi, Sihan Wu, Xiao Xiao, Lijun Chen, Lipeng Tang, Min Yan, Xiaoxiao Yang, Yaqian Tan, Pengxin Qiu, Yijun Huang, Wei Yin, Xinwen Su, Haiyan Hu, Jun Hu, Guangmei Yan

    Published 2014
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  11. 11
    Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

    Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers by Hoon Kim, Nam Nguyen, Kristen M. Turner, Sihan Wu, Amit D. Gujar, Jens Luebeck, Jihe Liu, Viraj Deshpande, Utkrisht Rajkumar, Sandeep Namburi, Samirkumar B. Amin, Eunhee Yi, Francesca Menghi, Johannes H. Schulte, Anton G. Henssen, Howard Y. Chang, Christine R. Beck, Paul S. Mischel, Vineet Bafna, Roel G.W. Verhaak

    Published 2020
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  12. 12
    The evolutionary dynamics of extrachromosomal DNA in human cancers

    The evolutionary dynamics of extrachromosomal DNA in human cancers by Joshua T. Lange, John C. Rose, Celine Chen, Yuriy Pichugin, Liangqi Xie, Jun Tang, King L. Hung, Kathryn E. Yost, Quanming Shi, Marcella L. Erb, Utkrisht Rajkumar, Sihan Wu, Sabine Taschner‐Mandl, Marie Bernkopf, Charles Swanton, Zhe Liu, Weini Huang, Howard Y. Chang, Vineet Bafna, Anton G. Henssen, Benjamin Werner, Paul S. Mischel

    Published 2022
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  13. 13
    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling by Junfeng Bi, Taka-Aki Ichu, Ciro Zanca, Huijun Yang, Wei Zhang, Yuchao Gu, Sudhir Chowdhry, Alex Reed, Shiro Ikegami, Kristen M. Turner, Wenjing Zhang, Genaro R. Villa, Sihan Wu, Oswald Quehenberger, William H. Yong, Harley I. Kornblum, Jeremy N. Rich, Timothy F. Cloughesy, Webster K. Cavenee, Frank B. Furnari, Benjamin F. Cravatt, Paul S. Mischel

    Published 2019
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  14. 14
    Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus

    Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus by Jens Luebeck, Alvin Wei Tian Ng, Patricia C. Galipeau, Xiaohong Li, Carissa A. Sanchez, Annalise Katz‐Summercorn, Hoon Kim, Sriganesh Jammula, Yudou He, Scott M. Lippman, Roel G.W. Verhaak, Carlo C. Maley, Ludmil B. Alexandrov, Brian J. Reid, Rebecca C. Fitzgerald, Thomas G. Paulson, Howard Y. Chang, Sihan Wu, Vineet Bafna, Paul S. Mischel

    Published 2023
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  15. 15
    Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug

    Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug by Junfeng Bi, Atif Ali Khan, Jun Tang, Aaron M. Armando, Sihan Wu, Wei Zhang, Ryan C. Gimple, Alex Reed, Hui Jing, Tomoyuki Koga, Ivy Tsz-Lo Wong, Yuchao Gu, Shunichiro Miki, Huijun Yang, Briana C. Prager, Ellis J. Curtis, Derek A. Wainwright, Frank B. Furnari, Jeremy N. Rich, Timothy F. Cloughesy, Harley I. Kornblum, Oswald Quehenberger, Andrey Rzhetsky, Benjamin F. Cravatt, Paul S. Mischel

    Published 2021
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  16. 16
    Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of <i>MYC</i> Paralogs

    Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of <i>MYC</i> Paralogs by Shreoshi Pal Choudhuri, Luc Girard, Jun Yi Stanley Lim, Jillian F. Wise, Braeden Freitas, Di Yang, Edmond Wong, Seth Hamilton, Victor D. Chien, Yoon Jung Kim, Collin Gilbreath, Jun Zhong, Sarah Phat, David T. Myers, Camilla L. Christensen, Hanieh Mazloom-Farsibaf, Marcello Stanzione, Kwok‐Kin Wong, Yin P. Hung, Anna F. Farago, Catherine B. Meador, Nicholas J. Dyson, Michael S. Lawrence, Sihan Wu, Benjamin J. Drapkin

    Published 2024
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  17. 17
    The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes

    The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes by Fan Xing, Yizhao Luan, Jing Cai, Sihan Wu, Jialuo Mai, Jiayu Gu, Haipeng Zhang, Kai Li, Yuan Lin, Xiao Xiao, Jiankai Liang, Yuan Li, Wenli Chen, Yaqian Tan, Longxiang Sheng, Bingzheng Lu, Wanjun Lu, Mingshi Gao, Pengxin Qiu, Xingwen Su, Wei Yin, Jun Hu, Zhongping Chen, Ke Sai, Jing Wang, Fu‐Rong Chen, Yinsheng Chen, Shida Zhu, Dongbing Liu, Shi‐Yuan Cheng, Zhi Xie, Wenbo Zhu, Guangmei Yan

    Published 2017
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  18. 18
    Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity

    Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity by Ciro Zanca, Genaro R. Villa, Jorge A. Benítez, Amy Haseley Thorne, Tomoyuki Koga, Matteo D’Antonio, Shiro Ikegami, Jianhui Ma, Antonia Boyer, Afsheen Banisadr, Nathan M. Jameson, Alison D. Parisian, Olesja Eliseeva, Gabriela F. Barnabé, Feng Liu, Sihan Wu, Huijun Yang, Jill Wykosky, Kelly A. Frazer, Vladislav V. Verkhusha, Maria Isaguliants, William A. Weiss, Timothy C. Gahman, Andrew K. Shiau, Clark C. Chen, Paul S. Mischel, Webster K. Cavenee, Frank B. Furnari

    Published 2017
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  19. 19
    Circular ecDNA promotes accessible chromatin and high oncogene expression

    Circular ecDNA promotes accessible chromatin and high oncogene expression by Sihan Wu, Kristen M. Turner, Nam Nguyen, Ramya Raviram, Marcella L. Erb, Jennifer Santini, Jens Luebeck, Utkrisht Rajkumar, Yarui Diao, Bin Li, Wenjing Zhang, Nathan M. Jameson, M. Ryan Corces, Jeffrey M. Granja, Xingqi Chen, Ceyda Çoruh, Armen Abnousi, Jack Houston, Zhen Ye, Rong Hu, Miao Yu, Hoon Kim, Julie A. Law, Roel G.W. Verhaak, Ming Hu, Frank B. Furnari, Howard Y. Chang, Bing Ren, Vineet Bafna, Paul S. Mischel

    Published 2019
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  20. 20
    ecDNA hubs drive cooperative intermolecular oncogene expression

    ecDNA hubs drive cooperative intermolecular oncogene expression by King L. Hung, Kathryn E. Yost, Liangqi Xie, Quanming Shi, Konstantin Helmsauer, Jens Luebeck, Robert Schöpflin, Joshua T. Lange, Rocío Chamorro González, Natasha E. Weiser, Celine Chen, Maria E. Valieva, Ivy Tsz-Lo Wong, Sihan Wu, Siavash R. Dehkordi, Connor V. Duffy, Katerina Kraft, Jun Tang, Julia A. Belk, John C. Rose, M. Ryan Corces, Jeffrey M. Granja, Rui Li, Utkrisht Rajkumar, Jordan Friedlein, Anindya Bagchi, Ansuman T. Satpathy, Robert Tjian, Stefan Mundlos, Vineet Bafna, Anton G. Henssen, Paul S. Mischel, Zhe Liu, Howard Y. Chang

    Published 2021
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