Søgeresultater - Shunsuke Kitajima

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  1. 1
    Intersection of retinoblastoma tumor suppressor function, stem cells, metabolism, and inflammation

    Intersection of retinoblastoma tumor suppressor function, stem cells, metabolism, and inflammation af Shunsuke Kitajima, Chiaki Takahashi

    Udgivet 2017
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  2. 2
    Targeting the loss of <scp>cGAS</scp>/<scp>STING</scp> signaling in cancer

    Targeting the loss of <scp>cGAS</scp>/<scp>STING</scp> signaling in cancer af Nobunari Sasaki, Mizuki Homme, Shunsuke Kitajima

    Udgivet 2023
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  3. 3
    Inflammation as a driver and vulnerability of KRAS mediated oncogenesis

    Inflammation as a driver and vulnerability of KRAS mediated oncogenesis af Shunsuke Kitajima, Rohit Thummalapalli, David A. Barbie

    Udgivet 2016
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  4. 4
    Rb Regulates DNA Damage Response and Cellular Senescence through E2F-Dependent Suppression of N-Ras Isoprenylation

    Rb Regulates DNA Damage Response and Cellular Senescence through E2F-Dependent Suppression of N-Ras Isoprenylation af Awad Shamma, Yujiro Takegami, Takao Miki, Shunsuke Kitajima, Makoto Noda, Takao Obara, Takahiro Okamoto, Chiaki Takahashi

    Udgivet 2009
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  5. 5
    RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity

    RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity af Teruyuki Muraguchi, Yujiro Takegami, Toshiyuki Ohtsuka, Shunsuke Kitajima, E. P. S. Chandana, Akira Omura, Takao Miki, Rei Takahashi, Naoya Matsumoto, Andreas Ludwig, Makoto Noda, Chiaki Takahashi

    Udgivet 2007
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  6. 6
    Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion

    Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion af Fengkai Li, Shunsuke Kitajima, Susumu Kohno, Akiyo Yoshida, Shoichiro Tange, Soichiro Sasaki, Nobuhiro Okada, Yuuki Nishimoto, Hayato Muranaka, Naoko Nagatani, Misa Suzuki, Sayuri Masuda, Tran C. Thai, Takumi Nishiuchi, Tomoaki Tanaka, David A. Barbie, Naofumi Mukaida, Chiaki Takahashi

    Udgivet 2019
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  7. 7
    Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer

    Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer af Shunsuke Kitajima, Elena Ivanova, Sujuan Guo, Ryohei Yoshida, Marco Campisi, Shriram K. Sundararaman, Shoichiro Tange, Yoichiro Mitsuishi, Tran C. Thai, Sayuri Masuda, Brandon Piel, Lynette M. Sholl, Paul T. Kirschmeier, Cloud P. Paweletz, Hideo Watanabe, Mamiko Yajima, David A. Barbie

    Udgivet 2018
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  8. 8
    Autophagy Inhibition Dysregulates TBK1 Signaling and Promotes Pancreatic Inflammation

    Autophagy Inhibition Dysregulates TBK1 Signaling and Promotes Pancreatic Inflammation af Shenghong Yang, Yu Imamura, Russell W. Jenkins, Israel Cañadas, Shunsuke Kitajima, Amir R. Aref, Arthur Brannon, Eiji Oki, Adam Castoreno, Zehua Zhu, Tran C. Thai, Jacob B. Reibel, Zhirong Qian, Shuji Ogino, Kwok‐Kin Wong, Hideo Baba, Alec C. Kimmelman, Marina Pasca di Magliano, David A. Barbie

    Udgivet 2016
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  9. 9
    ER Stress Signaling Promotes the Survival of Cancer “Persister Cells” Tolerant to EGFR Tyrosine Kinase Inhibitors

    ER Stress Signaling Promotes the Survival of Cancer “Persister Cells” Tolerant to EGFR Tyrosine Kinase Inhibitors af Hideki Terai, Shunsuke Kitajima, Danielle S. Potter, Yusuke Matsui, Laura Gutierrez Quiceno, Ting Chen, Tae Jung Kim, Maria Rusan, Tran C. Thai, Federica Piccioni, Katherine A. Donovan, Nicholas Kwiatkowski, Kunihiko Hinohara, Guo Wei, Nathanael S. Gray, Eric S. Fischer, Kwok‐Kin Wong, Teppei Shimamura, Anthony Letai, Peter S. Hammerman, David A. Barbie

    Udgivet 2017
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  10. 10
    Tumor-Derived cGAMP Regulates Activation of the Vasculature

    Tumor-Derived cGAMP Regulates Activation of the Vasculature af Marco Campisi, Shriram K. Sundararaman, Sarah E. Shelton, Erik H. Knelson, Navin R. Mahadevan, Ryohei Yoshida, Tetsuo Tani, Elena Ivanova, Israel Cañadas, Tatsuya Osaki, Sharon Wei Ling Lee, Tran C. Thai, Saemi Han, Brandon Piel, Sean Gilhooley, Cloud P. Paweletz, Valeria Chiono, Roger D. Kamm, Shunsuke Kitajima, David A. Barbie

    Udgivet 2020
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  11. 11
    3D microfluidic <i>ex vivo</i> culture of organotypic tumor spheroids to model immune checkpoint blockade

    3D microfluidic <i>ex vivo</i> culture of organotypic tumor spheroids to model immune checkpoint blockade af Amir Reza Aref, Marco Campisi, Elena Ivanova, Andrew Portell, Dalia Larios, Brandon Piel, Natasha Mathur, Chensheng W. Zhou, Raven Vlahos Coakley, Alan Bartels, Michaela Bowden, Zach Herbert, Sarah J. Hill, Sean Gilhooley, Jacob Carter, Israel Cañadas, Tran C. Thai, Shunsuke Kitajima, Valeria Chiono, Cloud P. Paweletz, David A. Barbie, Roger D. Kamm, Russell W. Jenkins

    Udgivet 2018
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  12. 12
    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS

    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS af Shunsuke Kitajima, Hajime Asahina, Ting Chen, Sujuan Guo, Laura Gutierrez Quiceno, Jillian D. Cavanaugh, Ashley A. Merlino, Shoichiro Tange, Hideki Terai, Jong Wook Kim, Xiaoen Wang, Shan Zhou, Man Xu, Stephen Wang, Zehua Zhu, Tran C. Thai, Chiaki Takahashi, Yujin Wang, Richard M. Neve, Susanna Stinson, Pablo Tamayo, Hideo Watanabe, Paul T. Kirschmeier, Kwok‐Kin Wong, David A. Barbie

    Udgivet 2018
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  13. 13
    Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade

    Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade af Kartik Sehgal, Andrew Portell, Elena Ivanova, Patrick H. Lizotte, Navin R. Mahadevan, Jonathan Greene, Amir Vajdi, Carino Gurjao, Tyler J. Teceno, Luke J. Taus, Tran C. Thai, Shunsuke Kitajima, Derek Liu, Tetsuo Tani, Moataz Noureddine, Christie J. Lau, Paul T. Kirschmeier, David Liu, Marios Giannakis, Russell W. Jenkins, Prafulla C. Gokhale, Silvia Goldoni, Maria Pinzon-Ortiz, William D. Hastings, Peter S. Hammerman, Juan J. Miret, Cloud P. Paweletz, David A. Barbie

    Udgivet 2020
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  14. 14
    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer

    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer af Shunsuke Kitajima, Tetsuo Tani, Benjamin F. Springer, Marco Campisi, Tatsuya Osaki, Koji Haratani, Minyue Chen, Erik H. Knelson, Navin R. Mahadevan, Jessica Ritter, Ryohei Yoshida, Jens Köhler, Atsuko Ogino, Ryu‐Suke Nozawa, Shriram K. Sundararaman, Tran C. Thai, Mizuki Homme, Brandon Piel, Sophie Kivlehan, Bonje Obua, Connor Purcell, Mamiko Yajima, Thanh U. Barbie, Patrick H. Lizotte, Pasi A. Jänne, Cloud P. Paweletz, Prafulla C. Gokhale, David A. Barbie

    Udgivet 2022
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  15. 15
    STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment

    STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment af Shohei Koyama, Esra A. Akbay, Yvonne Y. Li, Amir Reza Aref, Ferdinandos Skoulidis, Grit S. Herter-Sprie, Kevin A. Buczkowski, Yan Liu, Mark M. Awad, Warren L. Denning, Lixia Diao, Jing Wang, Edwin R. Parra-Cuentas, Ignacio I. Wistuba, Margaret Soucheray, Tran C. Thai, Hajime Asahina, Shunsuke Kitajima, Abigail Altabef, Jillian D. Cavanaugh, Kevin Rhee, Peng Gao, Haikuo Zhang, Peter E. Fecci, Takeshi Shimamura, Matthew D. Hellmann, John V. Heymach, F. Stephen Hodi, Gordon J. Freeman, David A. Barbie, Glenn Dranoff, Peter S. Hammerman, Kwok‐Kin Wong

    Udgivet 2016
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  16. 16
    Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States

    Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States af Jong Wook Kim, Omar O. Abudayyeh, Huwate Yeerna, Chen‐Hsiang Yeang, Michelle L. Stewart, Russell W. Jenkins, Shunsuke Kitajima, David J. Konieczkowski, Kate Medetgul-Ernar, Taylor B. Cavazos, Clarence K. Mah, Stephanie Ting, Eliezer M. Van Allen, Ofir Cohen, John McDermott, Emily Damato, Andrew J. Aguirre, Jonathan Liang, Arthur Liberzon, Gabriella Alexe, John G. Doench, Mahmoud Ghandi, Francisca Vázquez, Barbara A. Weir, Aviad Tsherniak, Aravind Subramanian, Karina Meneses-Cime, Jason Y. Park, Paul A. Clemons, Levi A. Garraway, David Thomas, Jesse S. Boehm, David A. Barbie, William C. Hahn, Jill P. Mesirov, Pablo Tamayo

    Udgivet 2017
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  17. 17
    Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses

    Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses af Israel Cañadas, Rohit Thummalapalli, Jong Wook Kim, Shunsuke Kitajima, Russell W. Jenkins, Camilla L. Christensen, Marco Campisi, Yanan Kuang, Yanxi Zhang, Evisa Gjini, Gao Zhang, Tian Tian, Debattama R. Sen, Diana Miao, Yu Imamura, Tran C. Thai, Brandon Piel, Hideki Terai, Amir Reza Aref, Timothy Hagan, Shohei Koyama, Masayuki Watanabe, Hideo Baba, Anika E. Adeni, Christine Lydon, Pablo Tamayo, Zhi Wei, Meenhard Herlyn, Thanh U. Barbie, Ravindra Uppaluri, Lynnette Marie Sholl, Ewa Sicińska, Jacob Sands, Scott J. Rodig, Kwok‐Kin Wong, Cloud P. Paweletz, Hideo Watanabe, David A. Barbie

    Udgivet 2018
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  18. 18
    Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity

    Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity af Navin R. Mahadevan, Erik H. Knelson, Jacquelyn O. Wolff, Amir Vajdi, Maria Saigí, Marco Campisi, Deli Hong, Tran C. Thai, Brandon Piel, Saemi Han, Bruce B. Reinhold, Jonathan S. Duke‐Cohan, Michael J. Poitras, Luke J. Taus, Patrick H. Lizotte, Andrew Portell, Victor Quadros, Alison Santucci, Takahiko Murayama, Israel Cañadas, Shunsuke Kitajima, Aoi Akitsu, Maya Fridrikh, Hideo Watanabe, Brendan Reardon, Prafulla C. Gokhale, Cloud P. Paweletz, Mark M. Awad, Eliezer M. Van Allen, Ana Lako, Xitao Wang, Bowen Chen, Fangxin Hong, Lynette M. Sholl, Michael Tolstorukov, Kathleen L. Pfaff, Pasi A. Jänne, Evisa Gjini, Robin Edwards, Scott J. Rodig, Ellis L. Reinherz, Matthew G. Oser, David A. Barbie

    Udgivet 2021
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  19. 19
    <i>Ex Vivo</i> Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

    <i>Ex Vivo</i> Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids af Russell W. Jenkins, Amir Reza Aref, Patrick H. Lizotte, Elena Ivanova, Susanna Stinson, Chensheng W. Zhou, Michaela Bowden, Jiehui Deng, Hongye Liu, Diana Miao, Meng Xiao He, William H. Walker, Gao Zhang, Tian Tian, Chaoran Cheng, Zhi Wei, Sangeetha Palakurthi, Mark Bittinger, Hans Vitzthum, Jong Wook Kim, Ashley A. Merlino, Max M. Quinn, Chandrasekar Venkataramani, Joshua A. Kaplan, Andrew Portell, Prafulla C. Gokhale, Bart Phillips, Alicia Smart, Asaf Rotem, Robert E. Jones, Lauren Keogh, María Anguiano, Lance Stapleton, Zhiheng Jia, Michal Barzily-Rokni, Israel Cañadas, Tran C. Thai, Marc R. Hammond, Raven Vlahos, Eric S. Wang, Hua Zhang, Shuai Li, Glenn J. Hanna, Wei Huang, Mai P. Hoang, Adriano Piris, Jean-Pierre Eliane, Anat Stemmer‐Rachamimov, Lisa Cameron, Mei-Ju Su, Parin Shah, Benjamin Izar, Manisha Thakuria, Nicole R. LeBoeuf, Guilherme Rabinowits, Viswanath Gunda, Sareh Parangi, James M. Cleary, Brian C. Miller, Shunsuke Kitajima, Rohit Thummalapalli, Benchun Miao, Thanh U. Barbie, Vivek Sivathanu, Joshua A. Wong, William G. Richards, Raphael Bueno, Charles H. Yoon, Juan J. Miret, Meenhard Herlyn, Levi A. Garraway, Eliezer M. Van Allen, Gordon J. Freeman, Paul T. Kirschmeier, Jochen H. Lorch, Patrick A. Ott, F. Stephen Hodi, Keith T. Flaherty, Roger D. Kamm, Genevieve M. Boland, Kwok‐Kin Wong, David Dornan, Cloud P. Paweletz, David A. Barbie

    Udgivet 2017
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