Search Results - Shriya Deshmukh

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  1. 1
    Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression

    Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression by Siddhant U. Jain, Sima Khazaei, Dylan M. Marchione, Stefan Lundgren, Xiaoshi Wang, Daniel N. Weinberg, Shriya Deshmukh, Nikoleta Juretic, Chao Lü, C. David Allis, Benjamin A. García, Nada Jabado, Peter W. Lewis

    Published 2020
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  2. 2
    PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

    PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism by Siddhant U. Jain, J. Truman, Peder J. Lund, Andrew Q. Rashoff, Katharine L. Diehl, Marcin Cieślik, Andrea Bajic, Nikoleta Juretic, Shriya Deshmukh, Sriram Venneti, Tom W. Muir, Benjamin A. García, Nada Jabado, Peter W. Lewis

    Published 2019
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  3. 3
    H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2

    H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2 by Siddhant U. Jain, Andrew Q. Rashoff, Samuel D. Krabbenhoft, Dominik Hoelper, J. Truman, Tyler J. Gibson, Stefan Lundgren, Eliana R. Bondra, Shriya Deshmukh, Ashot S. Harutyunyan, Nikoleta Juretic, Nada Jabado, Melissa M. Harrison, Peter W. Lewis

    Published 2020
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  4. 4
    Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas

    Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas by Brian Krug, Nicolas Jay, Ashot S. Harutyunyan, Shriya Deshmukh, Dylan M. Marchione, Paul Guilhamon, Kelsey C. Bertrand, Leonie G. Mikael, Melissa K. McConechy, Carol Chen, Sima Khazaei, Robert F. Koncar, Sameer Agnihotri, Damien Faury, Benjamin Ellezam, Alexander G. Weil, Josie Ursini‐Siegel, Daniel D. De Carvalho, Peter B. Dirks, Peter W. Lewis, Paolo Salomoni, Mathieu Lupien, C.H. Arrowsmith, Paul Lasko, Benjamin A. García, Claudia L. Kleinman, Nada Jabado, Stephen C. Mack

    Published 2019
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  5. 5
    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone

    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone by Sima Khazaei, Nicolas Jay, Shriya Deshmukh, Liam D. Hendrikse, Wajih Jawhar, Carol Chen, Leonie G. Mikael, Damien Faury, Dylan M. Marchione, Joël Lanoix, Éric Bonneil, Takeaki Ishii, Siddhant U. Jain, Kateryna Rossokhata, Tianna S. Sihota, Robert Eveleigh, Véronique Lisi, Ashot S. Harutyunyan, Sungmi Jung, Jason Karamchandani, Brendan C. Dickson, Robert Turcotte, Jay S. Wunder, Pierre Thibault, Peter W. Lewis, Benjamin A. García, Stephen C. Mack, Michael D. Taylor, Livia Garzia, Claudia L. Kleinman, Nada Jabado

    Published 2020
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  6. 6
    H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis

    H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis by Ashot S. Harutyunyan, Brian Krug, Haifeng Chen, Simon Papillon‐Cavanagh, Michele Zeinieh, Nicolas Jay, Shriya Deshmukh, Carol Chen, Jad I. Belle, Leonie G. Mikael, Dylan M. Marchione, Rui Li, Hamid Nikbakht, Bo Hu, Gaël Cagnone, Warren Cheung, Abdulshakour Mohammadnia, Denise Béchet, Damien Faury, Melissa K. McConechy, Manav Pathania, Siddhant U. Jain, Benjamin Ellezam, Alexander G. Weil, Alexandre Montpetit, Paolo Salomoni, Tomi Pastinen, Chao Lü, Peter W. Lewis, Benjamin A. García, Claudia L. Kleinman, Nada Jabado, Jacek Majewski

    Published 2019
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  7. 7
    DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells

    DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells by Jiil Chung, Yosef E. Maruvka, Sumedha Sudhaman, Jacalyn Kelly, Nicholas J. Haradhvala, Vanessa Bianchi, Melissa Edwards, Victoria J. Forster, Nuno M. Nunes, Melissa A. Galati, Martin Komosa, Shriya Deshmukh, Vanja Cabric, Scott Davidson, Matthew Zatzman, Nicholas Light, Reid Hayes, Ledia Brunga, Nathaniel D. Anderson, Ben Ho, Karl P. Hodel, Robert Siddaway, A. Sorana Morrissy, Daniel C. Bowers, Valérie Larouche, Annika Bronsema, Michael Osborn, Kristina A. Cole, Enrico Opocher, Gary Mason, Gregory A. Thomas, Ben George, David S. Ziegler, Scott Lindhorst, Magimairajan Vanan, Michal Yalon-Oren, Alyssa Reddy, Maura Massimino, Patrick Tomboc, An Van Damme, Alexander Lossos, Carol Durno, Melyssa Aronson, Daniel A. Morgenstern, Éric Bouffet, Annie Huang, Michael D. Taylor, Anita Villani, David Malkin, Cynthia Hawkins, Zachary F. Pursell, Adam Shlien, Thomas A. Kunkel, Gad Getz, Uri Tabori

    Published 2020
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  8. 8
    Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis

    Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis by Carol Chen, Shriya Deshmukh, Selin Jessa, Djihad Hadjadj, Véronique Lisi, Augusto Faria Andrade, Damien Faury, Wajih Jawhar, Rola Dali, Hiromichi Suzuki, Manav Pathania, A.M. Deli, Frank Dubois, E. L. Woodward, Steven Hébert, Marie Coutelier, Jason Karamchandani, Steffen Albrecht, Sebastian Brandner, Nicolas Jay, Tenzin Gayden, Andrea Bajic, Ashot S. Harutyunyan, Dylan M. Marchione, Leonie G. Mikael, Nikoleta Juretic, Michele Zeinieh, Caterina Russo, Nicola Maestro, Angelia V. Bassenden, Péter Hauser, József Virga, László Bognár, Álmos Klekner, Michal Zápotocký, Aleš Vícha, Lenka Krsková, Katerina Hadrava Vanova, Josef Zámečnı́k, David Sumerauer, Paul G. Ekert, David S. Ziegler, Benjamin Ellezam, Mariella G. Filbin, Mathieu Blanchette, Jordan R. Hansford, Dong-Anh Khuong-Quang, Albert M. Berghuis, Alexander G. Weil, Benjamin A. Garcia, Livia Garzia, Stephen C. Mack, Rameen Beroukhim, Keith L. Ligon, Michael D. Taylor, Pratiti Bandopadhayay, Christoph Kramm, Stefan M. Pfister, Andrey Korshunov, Dominik Sturm, David Jones, Paolo Salomoni, Claudia L. Kleinman, Nada Jabado

    Published 2020
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