Hakutulokset - Shivashankar Othy

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  1. 1
    Intravenous Gammaglobulin Inhibits Encephalitogenic Potential of Pathogenic T Cells and Interferes with their Trafficking to the Central Nervous System, Implicating Sphingosine-1 Phosphate Receptor 1–Mammalian Target of Rapamycin Axis

    Intravenous Gammaglobulin Inhibits Encephalitogenic Potential of Pathogenic T Cells and Interferes with their Trafficking to the Central Nervous System, Implicating Sphingosine-1 P... Tekijä Shivashankar Othy, Pushpa Hegde, Selma Topçu, Meenu Sharma, Mohan S. Maddur, Sébastien Lacroix‐Desmazes, Jagadeesh Bayry, Srini V. Kaveri

    Julkaistu 2013
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  2. 2
    T-cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse

    T-cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse Tekijä Hui Dong, Shivashankar Othy, Amit Jairaman, Jonathan Skupsky, Angel Zavala, Ian Parker, Joseph L. Dynes, Michael D. Cahalan

    Julkaistu 2017
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  3. 3
    Sialylation may be dispensable for reciprocal modulation of helper T cells by intravenous immunoglobulin

    Sialylation may be dispensable for reciprocal modulation of helper T cells by intravenous immunoglobulin Tekijä Shivashankar Othy, Selma Topçu, Chaitrali Saha, Prathap Kothapalli, Sébastien Lacroix‐Desmazes, Fabian Käsermann, Sylvia Miescher, Jagadeesh Bayry, Srini V. Kaveri

    Julkaistu 2014
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  4. 4
    Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming

    Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming Tekijä Melanie P. Matheu, Shivashankar Othy, Milton L. Greenberg, Hui Dong, Martijn J. Schuijs, Kim Deswarte, Hamida Hammad, Bart N. Lambrecht, Ian Parker, Michael D. Cahalan

    Julkaistu 2015
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  5. 5
    Regulatory T cells suppress Th17 cell Ca <sup>2+</sup> signaling in the spinal cord during murine autoimmune neuroinflammation

    Regulatory T cells suppress Th17 cell Ca <sup>2+</sup> signaling in the spinal cord during murine autoimmune neuroinflammation Tekijä Shivashankar Othy, Amit Jairaman, Joseph L. Dynes, Hui Dong, Cornelia Tune, Andriy V. Yeromin, Angel Zavala, Chijioke Akunwafo, Fangyi Chen, Ian Parker, Michael D. Cahalan

    Julkaistu 2020
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  6. 6
    Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing

    Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing Tekijä Hamza Atcha, Amit Jairaman, Jesse R. Holt, Vijaykumar S. Meli, Raji R. Nagalla, Praveen Krishna Veerasubramanian, Kyle T. Brumm, Huy E. Lim, Shivashankar Othy, Michael D. Cahalan, Medha M. Pathak, Wendy F. Liu

    Julkaistu 2021
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  7. 7
    Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop

    Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop Tekijä Francesco Marangoni, Ademi Zhakyp, Michela Corsini, Shannon N. Geels, Esteban Carrizosa, Martin Thelen, V. Mani, Jasper N. Prüßmann, Ross D. Warner, Aleksandra J. Ozga, Mauro Di Pilato, Shivashankar Othy, Thorsten R. Mempel

    Julkaistu 2021
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  8. 8
    TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia

    TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia Tekijä Amit Jairaman, Amanda McQuade, Alberto Granzotto, You Jung Kang, Jean Paul Chadarevian, Sunil Gandhi, Ian Parker, Ian F. Smith, Hansang Cho, Stefano L. Sensi, Shivashankar Othy, Mathew Blurton‐Jones, Michael D. Cahalan

    Julkaistu 2022
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  9. 9
    Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4 <sup>+</sup> T cell responses

    Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4 <sup>+</sup> T cell responses Tekijä Amit Jairaman, Shivashankar Othy, Joseph L. Dynes, Andriy V. Yeromin, Angel Zavala, Milton L. Greenberg, Jamison L. Nourse, Jesse R. Holt, Stuart M. Cahalan, Francesco Marangoni, Ian Parker, Medha M. Pathak, Michael D. Cahalan

    Julkaistu 2021
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  10. 10
    Regulatory T cells promote remyelination in the murine experimental autoimmune encephalomyelitis model of multiple sclerosis following human neural stem cell transplant

    Regulatory T cells promote remyelination in the murine experimental autoimmune encephalomyelitis model of multiple sclerosis following human neural stem cell transplant Tekijä Laura L. McIntyre, Scott A. Greilach, Shivashankar Othy, Ilse Sears‐Kraxberger, Brian Wi, Julio Ayala-Angulo, Estelle Vu, Quan Pham, Jorge Silva, Kody Dang, Fady Rezk, Oswald Steward, Michael D. Cahalan, Thomas E. Lane, Craig M. Walsh

    Julkaistu 2020
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  11. 11
    Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses

    Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses Tekijä Jessica L. Bolton, Annabel K. Short, Shivashankar Othy, Cassandra L. Kooiker, Manlin Shao, Benjamin G. Gunn, Jaclyn Beck, Xing‐Long Bai, Stephanie M. Law, Julie C. Savage, Jeremy J. Lambert, Delia Belelli, Marie‐Ève Tremblay, Michael D. Cahalan, Tallie Z. Baram

    Julkaistu 2022
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  12. 12
    Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

    Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis Tekijä Gérald Coulis, Diego Jaime, Christian F. Guerrero‐Juarez, Jenna M. Kastenschmidt, Philip K. Farahat, Quy Nguyen, Nicholas Pervolarakis, Katherine McLinden, Lauren Thurlow, Saba Movahedi, Brandon S. Hughes, Jorge Duarte, Andrew M. Sorn, Elizabeth Montoya, Izza Mozaffar, Morgan Dragan, Shivashankar Othy, Trupti Joshi, Chetan P. Hans, Virginia Kimonis, Adam L. MacLean, Qing Nie, Lindsay M. Wallace, Scott Q. Harper, Tahseen Mozaffar, Marshall W. Hogarth, Surajit Bhattacharya, Jyoti K. Jaiswal, David R. Golann, Qi Su, Kai Kessenbrock, Michael J. Stec, Melissa J. Spencer, Jesse R. Zamudio, S. Armando Villalta

    Julkaistu 2023
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