Suchergebnisse - Shinsuke Niwa

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  1. 1
    Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

    Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease von Nobutaka Hirokawa, Shinsuke Niwa, Yosuke Tanaka

    Veröffentlicht 2010
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  2. 2
    β-Tubulin mutations that cause severe neuropathies disrupt axonal transport

    β-Tubulin mutations that cause severe neuropathies disrupt axonal transport von Shinsuke Niwa, H. Takahashi, Nobutaka Hirokawa

    Veröffentlicht 2013
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  3. 3
    An <scp>ALS</scp>‐associated <scp>KIF5A</scp> mutant forms oligomers and aggregates and induces neuronal toxicity

    An <scp>ALS</scp>‐associated <scp>KIF5A</scp> mutant forms oligomers and aggregates and induces neuronal toxicity von Juri Nakano, Kyoko Chiba, Shinsuke Niwa

    Veröffentlicht 2022
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  4. 4
    Insight into the regulation of axonal transport from the study of KIF1A-associated neurological disorder

    Insight into the regulation of axonal transport from the study of KIF1A-associated neurological disorder von Kyoko Chiba, Tomoki Kita, Yuzu Anazawa, Shinsuke Niwa

    Veröffentlicht 2023
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  5. 5
    Going Too Far Is the Same as Falling Short†: Kinesin-3 Family Members in Hereditary Spastic Paraplegia

    Going Too Far Is the Same as Falling Short†: Kinesin-3 Family Members in Hereditary Spastic Paraplegia von Dominik R. Gabrych, Victor Lau, Shinsuke Niwa, Michael Silverman

    Veröffentlicht 2019
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  6. 6
    KIF26A Is an Unconventional Kinesin and Regulates GDNF-Ret Signaling in Enteric Neuronal Development

    KIF26A Is an Unconventional Kinesin and Regulates GDNF-Ret Signaling in Enteric Neuronal Development von Ruyun Zhou, Shinsuke Niwa, Noriko Homma, Yosuke Takei, Nobutaka Hirokawa

    Veröffentlicht 2009
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  7. 7
    Preferential binding of a kinesin-1 motor to GTP-tubulin–rich microtubules underlies polarized vesicle transport

    Preferential binding of a kinesin-1 motor to GTP-tubulin–rich microtubules underlies polarized vesicle transport von Takao Nakata, Shinsuke Niwa, Yasushi Okada, Franck Perez, Nobutaka Hirokawa

    Veröffentlicht 2011
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  8. 8
    De novo mutations in KIF1A-associated neuronal disorder (KAND) dominant-negatively inhibit motor activity and axonal transport of synaptic vesicle precursors

    De novo mutations in KIF1A-associated neuronal disorder (KAND) dominant-negatively inhibit motor activity and axonal transport of synaptic vesicle precursors von Yuzu Anazawa, Tomoki Kita, Rei Iguchi, Kumiko Hayashi, Shinsuke Niwa

    Veröffentlicht 2022
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  9. 9
    KIF19A Is a Microtubule-Depolymerizing Kinesin for Ciliary Length Control

    KIF19A Is a Microtubule-Depolymerizing Kinesin for Ciliary Length Control von Shinsuke Niwa, Kazuo Nakajima, Harukata Miki, Yusuke Minato, Doudou Wang, Nobutaka Hirokawa

    Veröffentlicht 2012
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  10. 10
    Synergistic autoinhibition and activation mechanisms control kinesin-1 motor activity

    Synergistic autoinhibition and activation mechanisms control kinesin-1 motor activity von Kyoko Chiba, Kassandra M Ori-McKenney, Shinsuke Niwa, Richard J. McKenney

    Veröffentlicht 2022
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  11. 11
    The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function

    The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function von Yosuke Tanaka, Shinsuke Niwa, Ming Dong, Atena Farkhondeh, Li Wang, Ruyun Zhou, Nobutaka Hirokawa

    Veröffentlicht 2016
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  12. 12
    Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses

    Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses von Shinsuke Niwa, David M. Lipton, Manatsu Morikawa, Charles Zhao, Nobutaka Hirokawa, Hang Lu, Kang Shen

    Veröffentlicht 2016
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  13. 13
    BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8

    BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8 von Shinsuke Niwa, Tao Li, Sharon Yuan-Fu Lu, Gerald Liew, Wei Feng, Maxence V. Nachury, Kang Shen

    Veröffentlicht 2017
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  14. 14
    Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors

    Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors von Kyoko Chiba, H. Takahashi, Min Chen, Hiroyuki Obinata, Shogo Arai, Koichi Hashimoto, Toshiyuki Oda, Richard J. McKenney, Shinsuke Niwa

    Veröffentlicht 2019
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  15. 15
    Structural basis for CRMP2-induced axonal microtubule formation

    Structural basis for CRMP2-induced axonal microtubule formation von Shinsuke Niwa, Fumio Nakamura, Yuri Tomabechi, Mari Aoki, Hideki Shigematsu, Takashi Matsumoto, Atsushi Yamagata, Shuya Fukai, Nobutaka Hirokawa, Yoshio Goshima, Mikako Shirouzu, Ryo Nitta

    Veröffentlicht 2017
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  16. 16
    A highly conserved 3 <sub>10</sub> helix within the kinesin motor domain is critical for kinesin function and human health

    A highly conserved 3 <sub>10</sub> helix within the kinesin motor domain is critical for kinesin function and human health von Aileen J. Lam, Lu Rao, Yuzu Anazawa, Kyoko Okada, Kyoko Chiba, Mariah Dacy, Shinsuke Niwa, Arne Gennerich, Dan W. Nowakowski, Richard J. McKenney

    Veröffentlicht 2021
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  17. 17
    The KASH protein UNC-83 differentially regulates kinesin-1 activity to control developmental stage-specific nuclear migration

    The KASH protein UNC-83 differentially regulates kinesin-1 activity to control developmental stage-specific nuclear migration von Selin Gümüşderelioğlu, Natalie Sahabandu, Daniel Elnatan, Ellen F. Gregory, Kyoko Chiba, Shinsuke Niwa, G.W. Gant Luxton, Richard J. McKenney, Daniel A. Starr

    Veröffentlicht 2025
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  18. 18
    A Combinatorial MAP Code Dictates Polarized Microtubule Transport

    A Combinatorial MAP Code Dictates Polarized Microtubule Transport von Brigette Y. Monroy, Tracy Tan, Janah May Oclaman, Jisoo S. Han, Sergi Simó, Shinsuke Niwa, Dan W. Nowakowski, Richard J. McKenney, Kassandra M Ori-McKenney

    Veröffentlicht 2020
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  19. 19
    A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability

    A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability von Poh Hui Chia, Franklin L. Zhong, Shinsuke Niwa, Carine Bonnard, Kagistia Hana Utami, Ruizhu Zeng, Hane Lee, Ascia Eskin, Stanley F. Nelson, William Xie, Samah Al‐Tawalbeh, Mohammad El-Khateeb, Mohammad Shboul, Mahmoud A. Pouladi, Mohammed Al‐Raqad, Bruno Reversade

    Veröffentlicht 2018
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  20. 20
    CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation

    CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation von Tsuyoshi Imasaki, Satoshi Kikkawa, Shinsuke Niwa, Yumiko Saijo‐Hamano, Hideki Shigematsu, Kazuhiro Aoyama, Kaoru Mitsuoka, Takahiro Shimizu, Mari Aoki, Ayako Sakamoto, Yuri Tomabechi, Naoki Sakai, Mikako Shirouzu, Shinya Taguchi, Yosuke Yamagishi, Tomiyoshi Setsu, Yoshiaki Sakihama, Eriko Nitta, Masatoshi Takeichi, Ryo Nitta

    Veröffentlicht 2022
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