检索结果 - Shinji Tsutsumi

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  1. 1
    Extracellular heat shock protein 90: A role for a molecular chaperone in cell motility and cancer metastasis

    Extracellular heat shock protein 90: A role for a molecular chaperone in cell motility and cancer metastasis 由 Shinji Tsutsumi, Len Neckers

    出版 2007
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  2. 2
    Hsp90 phosphorylation, Wee1 and the cell cycle

    Hsp90 phosphorylation, Wee1 and the cell cycle 由 Mehdi Mollapour, Shinji Tsutsumi, Len Neckers

    出版 2010
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  3. 3
    Impact of Heat-Shock Protein 90 on Cancer Metastasis

    Impact of Heat-Shock Protein 90 on Cancer Metastasis 由 Shinji Tsutsumi, Kristin Beebe, Len Neckers

    出版 2009
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  4. 4
    Low Dose Geldanamycin Inhibits Hepatocyte Growth Factor- and Hypoxia-Stimulated Invasion of Cancer Cells

    Low Dose Geldanamycin Inhibits Hepatocyte Growth Factor- and Hypoxia-Stimulated Invasion of Cancer Cells 由 Fumitaka Koga, Shinji Tsutsumi, Leonard Μ. Neckers

    出版 2007
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  5. 5
    NSAIDs induce both necrosis and apoptosis in guinea pig gastric mucosal cells in primary culture

    NSAIDs induce both necrosis and apoptosis in guinea pig gastric mucosal cells in primary culture 由 Wataru Tomisato, Shinji Tsutsumi, Kazuhito Rokutan, Tomofusa Tsuchiya, Tohru Mizushima

    出版 2001
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  6. 6
    Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity

    Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity 由 Mehdi Mollapour, Shinji Tsutsumi, Yeong Sang Kim, Jane B. Trepel, Len Neckers

    出版 2011
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  7. 7
    Prostaglandin E2 Protects Gastric Mucosal Cells from Apoptosis via EP2 and EP4 Receptor Activation

    Prostaglandin E2 Protects Gastric Mucosal Cells from Apoptosis via EP2 and EP4 Receptor Activation 由 Tatsuya Hoshino, Shinji Tsutsumi, Wataru Tomisato, Hyun-Jung Hwang, Tomofusa Tsuchiya, Tohru Mizushima

    出版 2003
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  8. 8
    Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone

    Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone 由 Akihiro Yano, Shinji Tsutsumi, Shiro Soga, Min-Jung Lee, Jane B. Trepel, Hiroyuki Osada, Len Neckers

    出版 2008
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  9. 9
    Heme Oxygenase-1 Protects Gastric Mucosal Cells against Non-steroidal Anti-inflammatory Drugs

    Heme Oxygenase-1 Protects Gastric Mucosal Cells against Non-steroidal Anti-inflammatory Drugs 由 Mayuko Aburaya, Ken‐ichiro Tanaka, Tatsuya Hoshino, Shinji Tsutsumi, Keitarou Suzuki, Masaki Makise, Reiko Akagi, Tohru Mizushima

    出版 2006
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  10. 10
    Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis

    Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis 由 Shinji Tsutsumi, Tomomi Gotoh, Wataru Tomisato, S. Mima, Tatsuya Hoshino, H-J Hwang, Hitomi Takenaka, Tomofusa Tsuchiya, Masataka Mori, T. Mizushima

    出版 2004
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  11. 11
    Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity

    Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity 由 Shinji Tsutsumi, Mehdi Mollapour, Chrisostomos Prodromou, Chung‐Tien Lee, Barry Panaretou, Soichiro Yoshida, Matthias P. Mayer, Leonard Μ. Neckers

    出版 2012
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  12. 12
    A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion

    A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion 由 Shinji Tsutsumi, Bradley T. Scroggins, Fumitaka Koga, Ming‐Jen Lee, Jane B. Trepel, Sara J. Felts, César Carreras Monfort, Len Neckers

    出版 2007
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  13. 13
    Involvement of Intracellular Ca2+ Levels in Nonsteroidal Anti-inflammatory Drug-induced Apoptosis

    Involvement of Intracellular Ca2+ Levels in Nonsteroidal Anti-inflammatory Drug-induced Apoptosis 由 Ken‐ichiro Tanaka, Wataru Tomisato, Tatsuya Hoshino, Tomoaki Ishihara, Takushi Namba, Mayuko Aburaya, Takashi Katsu, Keitarou Suzuki, Shinji Tsutsumi, Tohru Mizushima

    出版 2005
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  14. 14
    Vimentin expression of esophageal squamous cell carcinoma and its aggressive potential for lymph node metastasis

    Vimentin expression of esophageal squamous cell carcinoma and its aggressive potential for lymph node metastasis 由 Hiroyuki Jin, Satoko Morohashi, Fuyuki Sato, Yasuyuki Kudo, Harue Akasaka, Shinji Tsutsumi, Hiroshi Ogasawara, Keiichi Miyamoto, Naoki Wajima, Hitoshi Kawasaki, Kenichi Hakamada, Hiroshi Kijima

    出版 2010
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  15. 15
    Tumor-Intrinsic and Tumor-Extrinsic Factors Impacting Hsp90- Targeted Therapy

    Tumor-Intrinsic and Tumor-Extrinsic Factors Impacting Hsp90- Targeted Therapy 由 Soraya Alarcon, Mehdi Mollapour, M.-J. Lee, Shinji Tsutsumi, S. Lee, Y.S. Kim, Thomas L. Prince, Andrea B. Apolo, Giuseppe Giaccone, Wanping Xu, Len Neckers, Jane B. Trepel

    出版 2012
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  16. 16
    The HSP90 Inhibitor Ganetespib Synergizes with the MET Kinase Inhibitor Crizotinib in both Crizotinib-Sensitive and -Resistant MET-Driven Tumor Models

    The HSP90 Inhibitor Ganetespib Synergizes with the MET Kinase Inhibitor Crizotinib in both Crizotinib-Sensitive and -Resistant MET-Driven Tumor Models 由 Naoto Miyajima, Shinji Tsutsumi, Carole Sourbier, Kristin Beebe, Mehdi Mollapour, Candy Rivas, Soichiro Yoshida, Jane B. Trepel, Ying Huang, Manabu Tatokoro, Nobuo Shinohara, Katsuya Nonomura, Len Neckers

    出版 2013
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  17. 17
    An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

    An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function 由 Bradley T. Scroggins, Kenneth Robzyk, Dongxia Wang, Monica G. Marcu, Shinji Tsutsumi, Kristin Beebe, Robert J. Cotter, Sara J. Felts, David O. Toft, Larry M. Karnitz, Neal Rosen, Len Neckers

    出版 2007
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  18. 18
    Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants

    Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants 由 Thomas L. Prince, Toshiki Kijima, Manabu Tatokoro, Sunmin Lee, Shinji Tsutsumi, Kendrick Yim, Candy Rivas, Sylvia V. Alarcon, Harvey Schwartz, Kofi Khamit-Kush, Bradley T. Scroggins, Kristin Beebe, Jane B. Trepel, Len Neckers

    出版 2015
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  19. 19
    Threonine 22 Phosphorylation Attenuates Hsp90 Interaction with Cochaperones and Affects Its Chaperone Activity

    Threonine 22 Phosphorylation Attenuates Hsp90 Interaction with Cochaperones and Affects Its Chaperone Activity 由 Mehdi Mollapour, Shinji Tsutsumi, Andrew W. Truman, Wanping Xu, Cara K. Vaughan, Kristin Beebe, Anna A Konstantinova, Srinivas Vourganti, Barry Panaretou, Peter W. Piper, Jane B. Trepel, Chrisostomos Prodromou, Laurence H. Pearl, Len Neckers

    出版 2011
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  20. 20
    Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain

    Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain 由 Shinji Tsutsumi, Mehdi Mollapour, C. Graf, Chung‐Tien Lee, Bradley T. Scroggins, Wanping Xu, Lenka Haslerova, Martin Heßling, Anna A Konstantinova, Jane B. Trepel, Barry Panaretou, Johannes Büchner, Matthias P. Mayer, Chrisostomos Prodromou, Len Neckers

    出版 2009
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