Resultats de la cerca - Shih‐Chieh Chiang

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  1. 1
    ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in Neural Cells

    ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in Neural Cells per Meryem Alagöz, Shih‐Chieh Chiang, Abhishek Bharadwaj Sharma, Sherif F. El‐Khamisy

    Publicat 2013
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  2. 2
    SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair

    SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair per Jessica J. R. Hudson, Shih‐Chieh Chiang, Owen S. Wells, Chris Rookyard, Sherif F. El‐Khamisy

    Publicat 2012
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  3. 3
    Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical–induced DNA damage

    Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical–induced DNA damage per Shih‐Chieh Chiang, Martin Meagher, Nick Kassouf, Majid Hafezparast, Peter J. McKinnon, Rachel Haywood, Sherif F. El‐Khamisy

    Publicat 2017
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  4. 4
    Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks

    Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks per Claudia Kerzendorfer, Annabel Whibley, Gillian Carpenter, Emily Outwin, Shih‐Chieh Chiang, Gillian Turner, Charles E. Schwartz, Sherif F. El‐Khamisy, F. Lucy Raymond, Mark O’Driscoll

    Publicat 2010
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  5. 5
    Chemotherapy-induced COX-2 upregulation by cancer cells defines their inflammatory properties and limits the efficacy of chemoimmunotherapy combinations

    Chemotherapy-induced COX-2 upregulation by cancer cells defines their inflammatory properties and limits the efficacy of chemoimmunotherapy combinations per Charlotte R. Bell, Victoria S. Pelly, Agrin Moeini, Shih‐Chieh Chiang, Eimear Flanagan, Christian P. Bromley, Christopher Clark, Charles H. Earnshaw, Maria A. Koufaki, Eduardo Bonavita, Santiago Zelenay

    Publicat 2022
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  6. 6
    UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis

    UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis per Chunyan Liao, Ryan Beveridge, Jessica J. R. Hudson, J. D. Parker, Shih‐Chieh Chiang, Swagat Ray, Mohamed E. Ashour, Ian Sudbery, Mark J. Dickman, Sherif F. El‐Khamisy

    Publicat 2018
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  7. 7
    Anti-Inflammatory Drugs Remodel the Tumor Immune Environment to Enhance Immune Checkpoint Blockade Efficacy

    Anti-Inflammatory Drugs Remodel the Tumor Immune Environment to Enhance Immune Checkpoint Blockade Efficacy per Victoria S. Pelly, Agrin Moeini, Lisanne M. Roelofsen, Eduardo Bonavita, Charlotte R. Bell, Colin Hutton, Adrián Blanco‐Gómez, Antonia Banyard, Christian P. Bromley, Eimear Flanagan, Shih‐Chieh Chiang, Claus Jørgensen, Ton N. Schumacher, Daniela S. Thommen, Santiago Zelenay

    Publicat 2021
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  8. 8
    TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts

    TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts per John Fielden, Katherine Wiseman, Ignacio Torrecilla, Shudong Li, Samuel Hume, Shih‐Chieh Chiang, Annamaria Ruggiano, Abhay Narayan Singh, Raimundo Freire, Sylvana Hassanieh, Enric Domingo, Iolanda Vendrell, Román Fischer, Benedikt M. Kessler, Tim Maughan, Sherif F. El‐Khamisy, Kristijan Ramadan

    Publicat 2020
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  9. 9
    Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade

    Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade per Eduardo Bonavita, Christian P. Bromley, Gustav Jonsson, Victoria S. Pelly, Sudhakar Sahoo, Katherine Walwyn-Brown, Sofia Mensurado, Agrin Moeini, Eimear Flanagan, Charlotte R. Bell, Shih‐Chieh Chiang, C.P. Chikkanna-Gowda, Neil C. Rogers, Bruno Silva‐Santos, Sébastien Jaillon, Alberto Mantovani, Caetano Reis e Sousa, Nadia Guerra, Daniel M. Davis, Santiago Zelenay

    Publicat 2020
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  10. 10
    C9orf72 expansion disrupts ATM-mediated chromosomal break repair

    C9orf72 expansion disrupts ATM-mediated chromosomal break repair per Callum Walker, Saúl Herranz-Martín, Evangelia Karyka, Chunyan Liao, Katherine E. Lewis, Waheba Elsayed, Vera Lukashchuk, Shih‐Chieh Chiang, Swagat Ray, Pádraig J. Mulcahy, Mateusz Jurga, Ioannis Tsagakis, Tommaso Iannitti, Jayanth Chandran, Ian Coldicott, Kurt J. De Vos, Mohamed K. Hassan, Adrian Higginbottom, Pamela J. Shaw, Guillaume M. Hautbergue, Mimoun Azzouz, Sherif F. El‐Khamisy

    Publicat 2017
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