Search Results - Shi‐Yan Ng

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  1. 1
    Replacing what’s lost: a new era of stem cell therapy for Parkinson’s disease

    Replacing what’s lost: a new era of stem cell therapy for Parkinson’s disease by Yong Fan, Winanto Winanto, Shi‐Yan Ng

    Published 2020
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  2. 2
    Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors

    Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors by Shi‐Yan Ng, Rory Johnson, Lawrence W. Stanton

    Published 2011
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  3. 3
    Deciphering lipid dysregulation in ALS: from mechanisms to translational medicine

    Deciphering lipid dysregulation in ALS: from mechanisms to translational medicine by Ira Agrawal, Yong Shan Lim, Shi‐Yan Ng, Shuo‐Chien Ling

    Published 2022
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  4. 4
    The Long Noncoding RNA RMST Interacts with SOX2 to Regulate Neurogenesis

    The Long Noncoding RNA RMST Interacts with SOX2 to Regulate Neurogenesis by Shi‐Yan Ng, Gireesh K. Bogu, Boon-Seng Soh, Lawrence W. Stanton

    Published 2013
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  5. 5
    Organoid cultures of MELAS neural cells reveal hyperactive Notch signaling that impacts neurodevelopment

    Organoid cultures of MELAS neural cells reveal hyperactive Notch signaling that impacts neurodevelopment by Winanto Winanto, Zi Jian Khong, Boon-Seng Soh, Yong Fan, Shi‐Yan Ng

    Published 2020
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  6. 6
    Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy

    Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy by Mary H. Wertz, Kellen D. Winden, Pierre Neveu, Shi‐Yan Ng, Ebru Ercan, Mustafa Şahin

    Published 2016
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  7. 7
    Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy

    Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy by Shi‐Yan Ng, Boon-Seng Soh, Natalia Rodríguez‐Muela, David G. Hendrickson, Feodor D. Price, John L. Rinn, Lee L. Rubin

    Published 2015
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  8. 8
    Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes

    Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes by Yong Fan, Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Nicole Min Qian Pek, Jin Hui Hor, Shi‐Yan Ng, Boon-Seng Soh

    Published 2018
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  9. 9
    Label-Free and High-Throughput Removal of Residual Undifferentiated Cells From iPSC-Derived Spinal Cord Progenitor Cells

    Label-Free and High-Throughput Removal of Residual Undifferentiated Cells From iPSC-Derived Spinal Cord Progenitor Cells by Tan Dai Nguyen, Wai Hon Chooi, Hyungkook Jeon, Jiahui Chen, Jerome Tan, Daniel N. Roxby, Cheryl Yi‐Pin Lee, Shi‐Yan Ng, Sing Yian Chew, Jongyoon Han

    Published 2024
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  10. 10
    Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy

    Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy by Jin Hui Hor, Eunice Shi-Yi Soh, Li Yi Tan, Valerie Jing Wen Lim, Munirah Mohamad Santosa, Winanto Winanto, Beatrice Xuan Ho, Yong Fan, Boon-Seng Soh, Shi‐Yan Ng

    Published 2018
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  11. 11
    Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases

    Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases by Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Ying Chen, Yuin‐Han Loh, Ömer An, Henry Yang, Veerabrahma Pratap Seshachalam, Judice LY Koh, Woon‐Khiong Chan, Shi‐Yan Ng, Boon-Seng Soh

    Published 2022
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  12. 12
    ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation

    ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation by Jin‐Hui Hor, Munirah Mohamad Santosa, Valerie Jing Wen Lim, Beatrice Xuan Ho, Amy Taylor, Zi Jian Khong, John Ravits, Yong Fan, Yih‐Cherng Liou, Boon-Seng Soh, Shi‐Yan Ng

    Published 2020
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  13. 13
    The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy

    The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy by Constantin d’Ydewalle, Daniel M. Ramos, Noah J. Pyles, Shi‐Yan Ng, Mariusz Gorz, Celeste M. Pilato, Karen Ling, Lingling Kong, Amanda J. Ward, Lee L. Rubin, Frank Rigo, C. Frank Bennett, Charlotte J. Sumner

    Published 2016
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  14. 14
    CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis

    CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis by Samir Ounzain, Rudi Micheletti, Carme Arnan, Isabelle Plaisance, Dario Cecchi, Blanche Schroen, Ferrán Reverter, Michael Alexanian, Christine R. Gonzales, Shi‐Yan Ng, Giovanni Bussotti, Iole Pezzuto, Cédric Notredame, Stéphane Heymans, Roderic Guigó, Rory Johnson, Thierry Pedrazzini

    Published 2015
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  15. 15
    Correction: Corrigendum: Endothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells

    Correction: Corrigendum: Endothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells by Boon-Seng Soh, Shi‐Yan Ng, Hao Wu, Kristina Buac, Joo-Hye C. Park, Xiaojun Lian, Jiejia Xu, Kylie S. Foo, Ulrika Felldin, Xiaobing He, Massimo Nichane, Henry Yang, Lie Bu, Ronald A. Li, Bing Lim, Kenneth R. Chien

    Published 2016
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  16. 16
    Unveiling Sequence-Agnostic Mixed-Chemical Modification Patterns for Splice-Switching Oligonucleotides using the NATURA platform

    Unveiling Sequence-Agnostic Mixed-Chemical Modification Patterns for Splice-Switching Oligonucleotides using the NATURA platform by Tommaso Tabaglio, Taniya Agarwal, Wei Yuan Cher, Jin Rong Ow, Ah Keng Chew, Pan Sun, Raja Sekhar Reddy Gurrampati, Hongfang Lu, Praveena Naidu, H. Ng, Xavier Le Guezennec, Shi‐Yan Ng, Manikandan Lakshmanan, Ernesto Guccione, Keng Boon Wee

    Published 2025
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  17. 17
    Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease

    Single-Cell Analysis of SMN Reveals Its Broader Role in Neuromuscular Disease by Natalia Rodríguez‐Muela, Nadia K. Litterman, Erika M. Norabuena, Jesse L. Mull, María J. Galazo, Chicheng Sun, Shi‐Yan Ng, Nina R. Makhortova, Andrew J. White, Maureen M. Lynes, Wendy K. Chung, Lance S. Davidow, Jeffrey D. Macklis, Lee L. Rubin

    Published 2017
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  18. 18
    Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy

    Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy by Damien Meng-Kiat Leow, Yang Kai Ng, Loo Chien Wang, Hiromi W.L. Koh, Tianyun Zhao, Zi Jian Khong, Tommaso Tabaglio, Gunaseelan Narayanan, Richard M. Giadone, Radoslaw M. Sobota, Shi‐Yan Ng, Adrian Kee Keong Teo, Simon H. Parson, Lee L. Rubin, Wei‐Yi Ong, Basil T. Darras, Crystal Jing Jing Yeo

    Published 2024
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  19. 19
    TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination

    TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination by Wan Yun Ho, Jer‐Cherng Chang, Kenneth Teck Kiat Lim, Amaury Cazenave‐Gassiot, Aivi T. Nguyen, Juat Chin Foo, Sneha Muralidharan, Ashley Viera-Ortiz, Sarah J.M. Ong, Jin Hui Hor, Ira Agrawal, Shawn Hoon, Olubankole Aladesuyi Arogundade, María José Rodríguez-Álvarez, Su Min Lim, Seung Hyun Kim, John Ravits, Shi‐Yan Ng, Markus R. Wenk, Edward B. Lee, Greg Tucker‐Kellogg, Shuo‐Chien Ling

    Published 2021
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