Rezultati - Shcherbakov, Dimitri

Synthesis, ribosomal selectivity, and antibacterial activity of netilmicin 4′-derivatives od Sonousi, Amr, Shcherbakov, Dimitri, Vasella, Andrea, Böttger, Erik C., Crich, David

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N6′, N6‴, and O4′-Modifications to Neomycin Affect Ribosomal Selectivity Without Compromising Antibacterial Activity od Sati, Girish C., Shcherbakov, Dimitri, Hobbie, Sven, Vasella, Andrea, Böttger, Erik C., Crich, David

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Phylogenetic Sequence Variations in Bacterial rRNA Affect Species-Specific Susceptibility to Drugs Targeting Protein Synthesis od Akshay, Subramanian, Bertea, Mihai, Hobbie, Sven N., Oettinghaus, Björn, Shcherbakov, Dimitri, Böttger, Erik C., Akbergenov, Rashid

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Mitochondrial misreading in skeletal muscle accelerates metabolic aging and confers lipid accumulation and increased inflammation od Shcherbakov, Dimitri, Duscha, Stefan, Juskeviciene, Reda, Restelli, Lisa M., Frank, Stephan, Laczko, Endre, Böttger, Erik C.

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Mitochondrial Mistranslation in Brain Provokes a Metabolic Response Which Mitigates the Age-Associated Decline in Mitochondrial Gene Expression od Shcherbakov, Dimitri, Juskeviciene, Reda, Cortés Sanchón, Adrián, Brilkova, Margarita, Rehrauer, Hubert, Laczko, Endre, Böttger, Erik C.

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Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues. Importance of the Configuration at the 6′-Position and Differences Between the 6′-Amino and Hydroxy Series... od Mandhapati, Appi Reddy, Yang, Guanyu, Kato, Takayuki, Shcherbakov, Dimitri, Hobbie, Sven N., Vasella, Andrea, Böttger, Erik C., Crich, David

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Optimization of the antimicrobial peptide Bac7 by deep mutational scanning od Koch, Philipp, Schmitt, Steven, Heynisch, Alexander, Gumpinger, Anja, Wüthrich, Irene, Gysin, Marina, Shcherbakov, Dimitri, Hobbie, Sven N., Panke, Sven, Held, Martin

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ER-misfolded proteins become sequestered with mitochondria and impair mitochondrial function od Cortés Sanchón, Adrián, Santhosh Kumar, Harshitha, Mantovani, Matilde, Osinnii, Ivan, Mateos, José María, Kaech, Andres, Shcherbakov, Dimitri, Akbergenov, Rashid, Böttger, Erik C.

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Synthesis, antibacterial action, and ribosome inhibition of deoxyspectinomycins od Dharuman, Suresh, Wilt, Laura A., Liu, Jiuyu, Reeve, Stephanie M., Thompson, Carl W., Elmore, John M., Shcherbakov, Dimitri, Lee, Robin B., Böttger, Erik C., Lee, Richard E.

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Random errors in protein synthesis activate an age-dependent program of muscle atrophy in mice od Moore, James, Akbergenov, Rashid, Nigri, Martina, Isnard-Petit, Patricia, Grimm, Amandine, Seebeck, Petra, Restelli, Lisa, Frank, Stephan, Eckert, Anne, Thiam, Kader, Wolfer, David P., Shcherbakov, Dimitri, Böttger, Erik C.

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Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading od Juskeviciene, Reda, Fritz, Ann-Kristina, Brilkova, Margarita, Akbergenov, Rashid, Schmitt, Karen, Rehrauer, Hubert, Laczko, Endre, Isnard-Petit, Patricia, Thiam, Kader, Eckert, Anne, Schacht, Jochen, Wolfer, David P., Böttger, Erik C., Shcherbakov, Dimitri

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Identification and Evaluation of Improved 4′-O-(Alkyl) 4,5-Disubstituted 2-Deoxystreptamines as Next-Generation Aminoglycoside Antibiotics od Duscha, Stefan, Boukari, Heithem, Shcherbakov, Dimitri, Salian, Sumantha, Silva, Sandrina, Kendall, Ann, Kato, Takayuki, Akbergenov, Rashid, Perez-Fernandez, Deborah, Bernet, Bruno, Vaddi, Swapna, Thommes, Pia, Schacht, Jochen, Crich, David, Vasella, Andrea, Böttger, Erik C.

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Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resista... od Quirke, Jonathan C. K., Rajasekaran, Parasuraman, Sarpe, Vikram A, Sonousi, Amr, Osinnii, Ivan, Gysin, Marina, Haldimann, Klara, Fang, Qiao-Jun, Shcherbakov, Dimitri, Hobbie, Sven N., Sha, Su-Hua, Schacht, Jochen, Vasella, Andrea, Böttger, Erik C., Crich, David

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Premature aging in mice with error-prone protein synthesis od Shcherbakov, Dimitri, Nigri, Martina, Akbergenov, Rashid, Brilkova, Margarita, Mantovani, Matilde, Petit, Patricia Isnard, Grimm, Amandine, Karol, Agnieszka A., Teo, Youjin, Sanchón, Adrián Cortés, Kumar, Yadhu, Eckert, Anne, Thiam, Kader, Seebeck, Petra, Wolfer, David P., Böttger, Erik C.

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Mutant MRPS5 affects mitoribosomal accuracy and confers stress‐related behavioral alterations od Akbergenov, Rashid, Duscha, Stefan, Fritz, Ann‐Kristina, Juskeviciene, Reda, Oishi, Naoki, Schmitt, Karen, Shcherbakov, Dimitri, Teo, Youjin, Boukari, Heithem, Freihofer, Pietro, Isnard‐Petit, Patricia, Oettinghaus, Björn, Frank, Stephan, Thiam, Kader, Rehrauer, Hubert, Westhof, Eric, Schacht, Jochen, Eckert, Anne, Wolfer, David, Böttger, Erik C

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Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Ente... od Matsushita, Takahiko, Sati, Girish C., Kondasinghe, Nuwan, Pirrone, Michael G., Kato, Takayuki, Waduge, Prabuddha, Kumar, Harshitha Santhosh, Sanchon, Adrian Cortes, Dobosz-Bartoszek, Malgorzata, Shcherbakov, Dimitri, Juhas, Mario, Hobbie, Sven N., Schrepfer, Thomas, Chow, Christine S., Polikanov, Yury S., Schacht, Jochen, Vasella, Andrea, Böttger, Erik C., Crich, David

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