Хайлтын үр дүнгүүд - Shcherbakov, Dimitri

Synthesis, ribosomal selectivity, and antibacterial activity of netilmicin 4′-derivatives -н Sonousi, Amr, Shcherbakov, Dimitri, Vasella, Andrea, Böttger, Erik C., Crich, David

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N6′, N6‴, and O4′-Modifications to Neomycin Affect Ribosomal Selectivity Without Compromising Antibacterial Activity -н Sati, Girish C., Shcherbakov, Dimitri, Hobbie, Sven, Vasella, Andrea, Böttger, Erik C., Crich, David

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Phylogenetic Sequence Variations in Bacterial rRNA Affect Species-Specific Susceptibility to Drugs Targeting Protein Synthesis -н Akshay, Subramanian, Bertea, Mihai, Hobbie, Sven N., Oettinghaus, Björn, Shcherbakov, Dimitri, Böttger, Erik C., Akbergenov, Rashid

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Mitochondrial misreading in skeletal muscle accelerates metabolic aging and confers lipid accumulation and increased inflammation -н Shcherbakov, Dimitri, Duscha, Stefan, Juskeviciene, Reda, Restelli, Lisa M., Frank, Stephan, Laczko, Endre, Böttger, Erik C.

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Mitochondrial Mistranslation in Brain Provokes a Metabolic Response Which Mitigates the Age-Associated Decline in Mitochondrial Gene Expression -н Shcherbakov, Dimitri, Juskeviciene, Reda, Cortés Sanchón, Adrián, Brilkova, Margarita, Rehrauer, Hubert, Laczko, Endre, Böttger, Erik C.

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Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues. Importance of the Configuration at the 6′-Position and Differences Between the 6′-Amino and Hydroxy Series... -н Mandhapati, Appi Reddy, Yang, Guanyu, Kato, Takayuki, Shcherbakov, Dimitri, Hobbie, Sven N., Vasella, Andrea, Böttger, Erik C., Crich, David

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Optimization of the antimicrobial peptide Bac7 by deep mutational scanning -н Koch, Philipp, Schmitt, Steven, Heynisch, Alexander, Gumpinger, Anja, Wüthrich, Irene, Gysin, Marina, Shcherbakov, Dimitri, Hobbie, Sven N., Panke, Sven, Held, Martin

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ER-misfolded proteins become sequestered with mitochondria and impair mitochondrial function -н Cortés Sanchón, Adrián, Santhosh Kumar, Harshitha, Mantovani, Matilde, Osinnii, Ivan, Mateos, José María, Kaech, Andres, Shcherbakov, Dimitri, Akbergenov, Rashid, Böttger, Erik C.

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Synthesis, antibacterial action, and ribosome inhibition of deoxyspectinomycins -н Dharuman, Suresh, Wilt, Laura A., Liu, Jiuyu, Reeve, Stephanie M., Thompson, Carl W., Elmore, John M., Shcherbakov, Dimitri, Lee, Robin B., Böttger, Erik C., Lee, Richard E.

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Random errors in protein synthesis activate an age-dependent program of muscle atrophy in mice -н Moore, James, Akbergenov, Rashid, Nigri, Martina, Isnard-Petit, Patricia, Grimm, Amandine, Seebeck, Petra, Restelli, Lisa, Frank, Stephan, Eckert, Anne, Thiam, Kader, Wolfer, David P., Shcherbakov, Dimitri, Böttger, Erik C.

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Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading -н Juskeviciene, Reda, Fritz, Ann-Kristina, Brilkova, Margarita, Akbergenov, Rashid, Schmitt, Karen, Rehrauer, Hubert, Laczko, Endre, Isnard-Petit, Patricia, Thiam, Kader, Eckert, Anne, Schacht, Jochen, Wolfer, David P., Böttger, Erik C., Shcherbakov, Dimitri

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Identification and Evaluation of Improved 4′-O-(Alkyl) 4,5-Disubstituted 2-Deoxystreptamines as Next-Generation Aminoglycoside Antibiotics -н Duscha, Stefan, Boukari, Heithem, Shcherbakov, Dimitri, Salian, Sumantha, Silva, Sandrina, Kendall, Ann, Kato, Takayuki, Akbergenov, Rashid, Perez-Fernandez, Deborah, Bernet, Bruno, Vaddi, Swapna, Thommes, Pia, Schacht, Jochen, Crich, David, Vasella, Andrea, Böttger, Erik C.

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Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resista... -н Quirke, Jonathan C. K., Rajasekaran, Parasuraman, Sarpe, Vikram A, Sonousi, Amr, Osinnii, Ivan, Gysin, Marina, Haldimann, Klara, Fang, Qiao-Jun, Shcherbakov, Dimitri, Hobbie, Sven N., Sha, Su-Hua, Schacht, Jochen, Vasella, Andrea, Böttger, Erik C., Crich, David

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Premature aging in mice with error-prone protein synthesis -н Shcherbakov, Dimitri, Nigri, Martina, Akbergenov, Rashid, Brilkova, Margarita, Mantovani, Matilde, Petit, Patricia Isnard, Grimm, Amandine, Karol, Agnieszka A., Teo, Youjin, Sanchón, Adrián Cortés, Kumar, Yadhu, Eckert, Anne, Thiam, Kader, Seebeck, Petra, Wolfer, David P., Böttger, Erik C.

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Mutant MRPS5 affects mitoribosomal accuracy and confers stress‐related behavioral alterations -н Akbergenov, Rashid, Duscha, Stefan, Fritz, Ann‐Kristina, Juskeviciene, Reda, Oishi, Naoki, Schmitt, Karen, Shcherbakov, Dimitri, Teo, Youjin, Boukari, Heithem, Freihofer, Pietro, Isnard‐Petit, Patricia, Oettinghaus, Björn, Frank, Stephan, Thiam, Kader, Rehrauer, Hubert, Westhof, Eric, Schacht, Jochen, Eckert, Anne, Wolfer, David, Böttger, Erik C

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Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Ente... -н Matsushita, Takahiko, Sati, Girish C., Kondasinghe, Nuwan, Pirrone, Michael G., Kato, Takayuki, Waduge, Prabuddha, Kumar, Harshitha Santhosh, Sanchon, Adrian Cortes, Dobosz-Bartoszek, Malgorzata, Shcherbakov, Dimitri, Juhas, Mario, Hobbie, Sven N., Schrepfer, Thomas, Chow, Christine S., Polikanov, Yury S., Schacht, Jochen, Vasella, Andrea, Böttger, Erik C., Crich, David

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