Søgeresultater - Shcherbakov, Dimitri

Synthesis, ribosomal selectivity, and antibacterial activity of netilmicin 4′-derivatives af Sonousi, Amr, Shcherbakov, Dimitri, Vasella, Andrea, Böttger, Erik C., Crich, David

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N6′, N6‴, and O4′-Modifications to Neomycin Affect Ribosomal Selectivity Without Compromising Antibacterial Activity af Sati, Girish C., Shcherbakov, Dimitri, Hobbie, Sven, Vasella, Andrea, Böttger, Erik C., Crich, David

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Phylogenetic Sequence Variations in Bacterial rRNA Affect Species-Specific Susceptibility to Drugs Targeting Protein Synthesis af Akshay, Subramanian, Bertea, Mihai, Hobbie, Sven N., Oettinghaus, Björn, Shcherbakov, Dimitri, Böttger, Erik C., Akbergenov, Rashid

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Mitochondrial misreading in skeletal muscle accelerates metabolic aging and confers lipid accumulation and increased inflammation af Shcherbakov, Dimitri, Duscha, Stefan, Juskeviciene, Reda, Restelli, Lisa M., Frank, Stephan, Laczko, Endre, Böttger, Erik C.

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Mitochondrial Mistranslation in Brain Provokes a Metabolic Response Which Mitigates the Age-Associated Decline in Mitochondrial Gene Expression af Shcherbakov, Dimitri, Juskeviciene, Reda, Cortés Sanchón, Adrián, Brilkova, Margarita, Rehrauer, Hubert, Laczko, Endre, Böttger, Erik C.

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Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues. Importance of the Configuration at the 6′-Position and Differences Between the 6′-Amino and Hydroxy Series... af Mandhapati, Appi Reddy, Yang, Guanyu, Kato, Takayuki, Shcherbakov, Dimitri, Hobbie, Sven N., Vasella, Andrea, Böttger, Erik C., Crich, David

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Optimization of the antimicrobial peptide Bac7 by deep mutational scanning af Koch, Philipp, Schmitt, Steven, Heynisch, Alexander, Gumpinger, Anja, Wüthrich, Irene, Gysin, Marina, Shcherbakov, Dimitri, Hobbie, Sven N., Panke, Sven, Held, Martin

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ER-misfolded proteins become sequestered with mitochondria and impair mitochondrial function af Cortés Sanchón, Adrián, Santhosh Kumar, Harshitha, Mantovani, Matilde, Osinnii, Ivan, Mateos, José María, Kaech, Andres, Shcherbakov, Dimitri, Akbergenov, Rashid, Böttger, Erik C.

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Synthesis, antibacterial action, and ribosome inhibition of deoxyspectinomycins af Dharuman, Suresh, Wilt, Laura A., Liu, Jiuyu, Reeve, Stephanie M., Thompson, Carl W., Elmore, John M., Shcherbakov, Dimitri, Lee, Robin B., Böttger, Erik C., Lee, Richard E.

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Random errors in protein synthesis activate an age-dependent program of muscle atrophy in mice af Moore, James, Akbergenov, Rashid, Nigri, Martina, Isnard-Petit, Patricia, Grimm, Amandine, Seebeck, Petra, Restelli, Lisa, Frank, Stephan, Eckert, Anne, Thiam, Kader, Wolfer, David P., Shcherbakov, Dimitri, Böttger, Erik C.

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Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading af Juskeviciene, Reda, Fritz, Ann-Kristina, Brilkova, Margarita, Akbergenov, Rashid, Schmitt, Karen, Rehrauer, Hubert, Laczko, Endre, Isnard-Petit, Patricia, Thiam, Kader, Eckert, Anne, Schacht, Jochen, Wolfer, David P., Böttger, Erik C., Shcherbakov, Dimitri

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Identification and Evaluation of Improved 4′-O-(Alkyl) 4,5-Disubstituted 2-Deoxystreptamines as Next-Generation Aminoglycoside Antibiotics af Duscha, Stefan, Boukari, Heithem, Shcherbakov, Dimitri, Salian, Sumantha, Silva, Sandrina, Kendall, Ann, Kato, Takayuki, Akbergenov, Rashid, Perez-Fernandez, Deborah, Bernet, Bruno, Vaddi, Swapna, Thommes, Pia, Schacht, Jochen, Crich, David, Vasella, Andrea, Böttger, Erik C.

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Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resista... af Quirke, Jonathan C. K., Rajasekaran, Parasuraman, Sarpe, Vikram A, Sonousi, Amr, Osinnii, Ivan, Gysin, Marina, Haldimann, Klara, Fang, Qiao-Jun, Shcherbakov, Dimitri, Hobbie, Sven N., Sha, Su-Hua, Schacht, Jochen, Vasella, Andrea, Böttger, Erik C., Crich, David

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Premature aging in mice with error-prone protein synthesis af Shcherbakov, Dimitri, Nigri, Martina, Akbergenov, Rashid, Brilkova, Margarita, Mantovani, Matilde, Petit, Patricia Isnard, Grimm, Amandine, Karol, Agnieszka A., Teo, Youjin, Sanchón, Adrián Cortés, Kumar, Yadhu, Eckert, Anne, Thiam, Kader, Seebeck, Petra, Wolfer, David P., Böttger, Erik C.

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Mutant MRPS5 affects mitoribosomal accuracy and confers stress‐related behavioral alterations af Akbergenov, Rashid, Duscha, Stefan, Fritz, Ann‐Kristina, Juskeviciene, Reda, Oishi, Naoki, Schmitt, Karen, Shcherbakov, Dimitri, Teo, Youjin, Boukari, Heithem, Freihofer, Pietro, Isnard‐Petit, Patricia, Oettinghaus, Björn, Frank, Stephan, Thiam, Kader, Rehrauer, Hubert, Westhof, Eric, Schacht, Jochen, Eckert, Anne, Wolfer, David, Böttger, Erik C

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Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Ente... af Matsushita, Takahiko, Sati, Girish C., Kondasinghe, Nuwan, Pirrone, Michael G., Kato, Takayuki, Waduge, Prabuddha, Kumar, Harshitha Santhosh, Sanchon, Adrian Cortes, Dobosz-Bartoszek, Malgorzata, Shcherbakov, Dimitri, Juhas, Mario, Hobbie, Sven N., Schrepfer, Thomas, Chow, Christine S., Polikanov, Yury S., Schacht, Jochen, Vasella, Andrea, Böttger, Erik C., Crich, David

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