Resultats de la cerca - Shcherbakov, Dimitri

Synthesis, ribosomal selectivity, and antibacterial activity of netilmicin 4′-derivatives per Sonousi, Amr, Shcherbakov, Dimitri, Vasella, Andrea, Böttger, Erik C., Crich, David

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N6′, N6‴, and O4′-Modifications to Neomycin Affect Ribosomal Selectivity Without Compromising Antibacterial Activity per Sati, Girish C., Shcherbakov, Dimitri, Hobbie, Sven, Vasella, Andrea, Böttger, Erik C., Crich, David

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Phylogenetic Sequence Variations in Bacterial rRNA Affect Species-Specific Susceptibility to Drugs Targeting Protein Synthesis per Akshay, Subramanian, Bertea, Mihai, Hobbie, Sven N., Oettinghaus, Björn, Shcherbakov, Dimitri, Böttger, Erik C., Akbergenov, Rashid

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Mitochondrial misreading in skeletal muscle accelerates metabolic aging and confers lipid accumulation and increased inflammation per Shcherbakov, Dimitri, Duscha, Stefan, Juskeviciene, Reda, Restelli, Lisa M., Frank, Stephan, Laczko, Endre, Böttger, Erik C.

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Mitochondrial Mistranslation in Brain Provokes a Metabolic Response Which Mitigates the Age-Associated Decline in Mitochondrial Gene Expression per Shcherbakov, Dimitri, Juskeviciene, Reda, Cortés Sanchón, Adrián, Brilkova, Margarita, Rehrauer, Hubert, Laczko, Endre, Böttger, Erik C.

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Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues. Importance of the Configuration at the 6′-Position and Differences Between the 6′-Amino and Hydroxy Series... per Mandhapati, Appi Reddy, Yang, Guanyu, Kato, Takayuki, Shcherbakov, Dimitri, Hobbie, Sven N., Vasella, Andrea, Böttger, Erik C., Crich, David

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Optimization of the antimicrobial peptide Bac7 by deep mutational scanning per Koch, Philipp, Schmitt, Steven, Heynisch, Alexander, Gumpinger, Anja, Wüthrich, Irene, Gysin, Marina, Shcherbakov, Dimitri, Hobbie, Sven N., Panke, Sven, Held, Martin

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ER-misfolded proteins become sequestered with mitochondria and impair mitochondrial function per Cortés Sanchón, Adrián, Santhosh Kumar, Harshitha, Mantovani, Matilde, Osinnii, Ivan, Mateos, José María, Kaech, Andres, Shcherbakov, Dimitri, Akbergenov, Rashid, Böttger, Erik C.

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Synthesis, antibacterial action, and ribosome inhibition of deoxyspectinomycins per Dharuman, Suresh, Wilt, Laura A., Liu, Jiuyu, Reeve, Stephanie M., Thompson, Carl W., Elmore, John M., Shcherbakov, Dimitri, Lee, Robin B., Böttger, Erik C., Lee, Richard E.

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Random errors in protein synthesis activate an age-dependent program of muscle atrophy in mice per Moore, James, Akbergenov, Rashid, Nigri, Martina, Isnard-Petit, Patricia, Grimm, Amandine, Seebeck, Petra, Restelli, Lisa, Frank, Stephan, Eckert, Anne, Thiam, Kader, Wolfer, David P., Shcherbakov, Dimitri, Böttger, Erik C.

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Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading per Juskeviciene, Reda, Fritz, Ann-Kristina, Brilkova, Margarita, Akbergenov, Rashid, Schmitt, Karen, Rehrauer, Hubert, Laczko, Endre, Isnard-Petit, Patricia, Thiam, Kader, Eckert, Anne, Schacht, Jochen, Wolfer, David P., Böttger, Erik C., Shcherbakov, Dimitri

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Identification and Evaluation of Improved 4′-O-(Alkyl) 4,5-Disubstituted 2-Deoxystreptamines as Next-Generation Aminoglycoside Antibiotics per Duscha, Stefan, Boukari, Heithem, Shcherbakov, Dimitri, Salian, Sumantha, Silva, Sandrina, Kendall, Ann, Kato, Takayuki, Akbergenov, Rashid, Perez-Fernandez, Deborah, Bernet, Bruno, Vaddi, Swapna, Thommes, Pia, Schacht, Jochen, Crich, David, Vasella, Andrea, Böttger, Erik C.

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Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resista... per Quirke, Jonathan C. K., Rajasekaran, Parasuraman, Sarpe, Vikram A, Sonousi, Amr, Osinnii, Ivan, Gysin, Marina, Haldimann, Klara, Fang, Qiao-Jun, Shcherbakov, Dimitri, Hobbie, Sven N., Sha, Su-Hua, Schacht, Jochen, Vasella, Andrea, Böttger, Erik C., Crich, David

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Premature aging in mice with error-prone protein synthesis per Shcherbakov, Dimitri, Nigri, Martina, Akbergenov, Rashid, Brilkova, Margarita, Mantovani, Matilde, Petit, Patricia Isnard, Grimm, Amandine, Karol, Agnieszka A., Teo, Youjin, Sanchón, Adrián Cortés, Kumar, Yadhu, Eckert, Anne, Thiam, Kader, Seebeck, Petra, Wolfer, David P., Böttger, Erik C.

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Mutant MRPS5 affects mitoribosomal accuracy and confers stress‐related behavioral alterations per Akbergenov, Rashid, Duscha, Stefan, Fritz, Ann‐Kristina, Juskeviciene, Reda, Oishi, Naoki, Schmitt, Karen, Shcherbakov, Dimitri, Teo, Youjin, Boukari, Heithem, Freihofer, Pietro, Isnard‐Petit, Patricia, Oettinghaus, Björn, Frank, Stephan, Thiam, Kader, Rehrauer, Hubert, Westhof, Eric, Schacht, Jochen, Eckert, Anne, Wolfer, David, Böttger, Erik C

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Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Ente... per Matsushita, Takahiko, Sati, Girish C., Kondasinghe, Nuwan, Pirrone, Michael G., Kato, Takayuki, Waduge, Prabuddha, Kumar, Harshitha Santhosh, Sanchon, Adrian Cortes, Dobosz-Bartoszek, Malgorzata, Shcherbakov, Dimitri, Juhas, Mario, Hobbie, Sven N., Schrepfer, Thomas, Chow, Christine S., Polikanov, Yury S., Schacht, Jochen, Vasella, Andrea, Böttger, Erik C., Crich, David

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