Search Results - Shakchhi Joshi

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  1. 1
    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis

    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis by Sarah A. Tucker, Song-Hua Hu, Sejal Vyas, Albert Park, Shakchhi Joshi, Aslihan Inal, Tiffany Lam, Emily Tan, Kevin M. Haigis, Marcia C. Haigis

    Published 2024
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  2. 2
    Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

    Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells by Ilaria Elia, Jared H. Rowe, Sheila Johnson, Shakchhi Joshi, Giulia Notarangelo, Kiran Kurmi, Sarah A. Weiss, Gordon J. Freeman, Arlene H. Sharpe, Marcia C. Haigis

    Published 2022
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  3. 3
    Intrinsic myocardial defects underlie an Rbfox-deficient zebrafish model of hypoplastic left heart syndrome

    Intrinsic myocardial defects underlie an Rbfox-deficient zebrafish model of hypoplastic left heart syndrome by Mengmeng Huang, Alexander A. Akerberg, Xiaoran Zhang, Haejin Yoon, Shakchhi Joshi, Celia Hallinan, Christopher Nguyen, William T. Pu, Marcia C. Haigis, C. Geoffrey Burns, Caroline E. Burns

    Published 2022
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  4. 4
    Widespread neuroanatomical integration and distinct electrophysiological properties of glioma-innervating neurons

    Widespread neuroanatomical integration and distinct electrophysiological properties of glioma-innervating neurons by Annie L. Hsieh, Sanika Ganesh, Tomasz Kula, Madiha Irshad, Emily Ferenczi, Wengang Wang, Yi-Ching Chen, Song-Hua Hu, Zongyu Li, Shakchhi Joshi, Marcia C. Haigis, Bernardo L. Sabatini

    Published 2024
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  5. 5
    SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis

    SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis by Elma Zaganjor, Haejin Yoon, Jessica B. Spinelli, Elizabeth R. Nunn, Gaëlle Laurent, Paulina Keskinidis, Suganja Sivaloganathan, Shakchhi Joshi, Giulia Notarangelo, Stacy Mulei, Mathew T. Chvasta, Sarah A. Tucker, Krystle C. Kalafut, Robert A. H. van de Ven, Clary B. Clish, Marcia C. Haigis

    Published 2021
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  6. 6
    Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade

    Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade by Jared H. Rowe, Ilaria Elia, Osmaan Shahid, Emily F. Gaudiano, Natalia E. Sifnugel, Sheila Johnson, Amy G. Reynolds, Megan E. Fung, Shakchhi Joshi, Martin W. LaFleur, Joon Seok Park, Kristen E. Pauken, Joshua D. Rabinowitz, Gordon J. Freeman, Marcia C. Haigis, Arlene H. Sharpe

    Published 2023
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  7. 7
    Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

    Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity by Alison E. Ringel, Jefte M. Drijvers, Gregory J. Baker, Alessia Catozzi, Juan Carlos García‐Cañaveras, Brandon M. Gassaway, Brian C. Miller, Vikram R. Juneja, Thao H. Nguyen, Shakchhi Joshi, Cong-Hui Yao, Haejin Yoon, Peter T. Sage, Martin W. LaFleur, Justin D. Trombley, Connor A. Jacobson, Zoltan Maliga, Steven P. Gygi, Peter K. Sorger, Joshua D. Rabinowitz, Arlene H. Sharpe, Marcia C. Haigis

    Published 2020
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  8. 8
    Oncometabolite <scp>d</scp> -2HG alters T cell metabolism to impair CD8 <sup>+</sup> T cell function

    Oncometabolite <scp>d</scp> -2HG alters T cell metabolism to impair CD8 <sup>+</sup> T cell function by Giulia Notarangelo, Jessica B. Spinelli, Elizabeth M. Perez, Gregory J. Baker, Kiran Kurmi, Ilaria Elia, Sylwia A. Stopka, Gerard Baquer, Jia‐Ren Lin, Alexandra J. Golby, Shakchhi Joshi, Heide F. Baron, Jefte M. Drijvers, Peter Georgiev, Alison E. Ringel, Elma Zaganjor, Samuel K. McBrayer, Peter K. Sorger, Arlene H. Sharpe, Kai W. Wucherpfennig, Sandro Santagata, Nathalie Y.R. Agar, Mario L. Suvà, Marcia C. Haigis

    Published 2022
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