Risultati della ricerca - Seung‐Hwan Kwon
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α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism di Seung Pil Yun, Donghoon Kim, Sangjune Kim, Sang‐Min Kim, Senthilkumar S. Karuppagounder, Seung‐Hwan Kwon, Saebom Lee, Tae‐In Kam, Su-Hyun Lee, Sangwoo Ham, Jae Hong Park, Valina L. Dawson, Ted M. Dawson, Yunjong Lee, Han Seok Ko
Pubblicazione 2018Artigo -
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Complement and Coagulation Cascades are Potentially Involved in Dopaminergic Neurodegeneration in α-Synuclein-Based Mouse Models of Parkinson’s Disease di Shi-Xun Ma, Bo Am Seo, Donghoon Kim, Yulan Xiong, Seung‐Hwan Kwon, Saurav Brahmachari, Sangjune Kim, Tae‐In Kam, Raja Sekhar Nirujogi, Sang Ho Kwon, Valina L. Dawson, Ted M. Dawson, Akhilesh Pandey, Chan Hyun Na, Han Seok Ko
Pubblicazione 2021Artigo -
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GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers di Sangjune Kim, Seung Pil Yun, Saebom Lee, George K. E. Umanah, Veera Venkata Ratnam Bandaru, Xiling Yin, Peter Rhee, Senthilkumar S. Karuppagounder, Seung‐Hwan Kwon, Hojae Lee, Xiaobo Mao, Donghoon Kim, Akhilesh Pandey, Gabsang Lee, Valina L. Dawson, Ted M. Dawson, Han Seok Ko
Pubblicazione 2018Artigo -
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The c-Abl inhibitor, Radotinib HCl, is neuroprotective in a preclinical Parkinson’s disease mouse model di Saebom Lee, Sangjune Kim, Yong Joo Park, Seung Pil Yun, Seung‐Hwan Kwon, Donghoon Kim, Dong-Yeon Kim, Jae Soo Shin, Dae Jin Cho, Gong Yeal Lee, Hyun Ju, Hyo Jung Yun, Jae Hong Park, Richard W. Kim, Eun Ah Jung, Seulki Lee, Han Seok Ko
Pubblicazione 2018Artigo -
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Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease di Sangjune Kim, Seung‐Hwan Kwon, Tae‐In Kam, Nikhil Panicker, Senthilkumar S. Karuppagounder, Saebom Lee, Jun Hee Lee, Richard W. Kim, Minjee Kook, Catherine A. Foss, Chen‐Tian Shen, Hojae Lee, Subhash Kulkarni, Pankaj J. Pasricha, Gabsang Lee, Martin G. Pomper, Valina L. Dawson, Ted M. Dawson, Han Seok Ko
Pubblicazione 2019Artigo -
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Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease di Jong Sung Park, Tae‐In Kam, Saebom Lee, Hyejin Park, Yumin Oh, Seung‐Hwan Kwon, Jae‐Jin Song, Donghoon Kim, Hyunhee Kim, Aanishaa Jhaldiyal, Dong Hee Na, Kang Choon Lee, Eun Ji Park, Martin G. Pomper, Olga Pletniková, Juan C. Troncoso, Han Seok Ko, Valina L. Dawson, Ted M. Dawson, Seulki Lee
Pubblicazione 2021Artigo -
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Graphene quantum dots prevent α-synucleinopathy in Parkinson’s disease di Donghoon Kim, Je Min Yoo, Heehong Hwang, Junghee Lee, Su Hyun Lee, Seung Pil Yun, Myung Jin Park, Minjun Lee, Seulah Choi, Sang Ho Kwon, Saebom Lee, Seung‐Hwan Kwon, Sangjune Kim, Yong Joo Park, Misaki Kinoshita, Young Ho Lee, Seokmin Shin, Seung R. Paik, Sung Joong Lee, Seulki Lee, Byung Hee Hong, Han Seok Ko
Pubblicazione 2018Artigo -
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TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease di Bo Am Seo, Donghoon Kim, Heehong Hwang, Min Seong Kim, Shi‐Xun Ma, Seung‐Hwan Kwon, Sin Ho Kweon, Hu Wang, Je Min Yoo, Seulah Choi, Sang Ho Kwon, Sung-Ung Kang, Tae‐In Kam, Kwang‐Soo Kim, Senthilkumar S. Karuppagounder, Bong Gu Kang, Saebom Lee, Hyejin Park, Sangjune Kim, Wei Yan, Yong-Shi Li, Sheng-Han Kuo, Javier Redding‐Ochoa, Olga Pletniková, Juan C. Troncoso, Gabsang Lee, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Han Seok Ko
Pubblicazione 2021Artigo -
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Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease di Seung Pil Yun, Tae‐In Kam, Nikhil Panicker, Sang‐Min Kim, Yumin Oh, Jong Sung Park, Seung‐Hwan Kwon, Yong Joo Park, Senthilkumar S. Karuppagounder, Hyejin Park, Sangjune Kim, Nayeon Oh, Nayoung Alice Kim, Saebom Lee, Saurav Brahmachari, Xiaobo Mao, Jun Hee Lee, Manoj Kumar, Daniel An, Sung-Ung Kang, Yunjong Lee, Kang Choon Lee, Dong Hee Na, Donghoon Kim, Sang Hun Lee, Viktor Roschke, Shane A. Liddelow, Zoltán Mari, Ben A. Barres, Valina L. Dawson, Seulki Lee, Ted M. Dawson, Han Seok Ko
Pubblicazione 2018Artigo
Strumenti per la ricerca:
Soggetti correlati
Medicine
Biology
Disease
Neuroscience
Parkinson's disease
Biochemistry
Dopamine
Chemistry
Dopaminergic
Gene
Internal medicine
Pharmacology
Cell biology
Neurodegeneration
Neuroprotection
Pathology
Receptor
Alpha-synuclein
Central nervous system
Agonist
Antioxidant
Astrocyte
Enzyme
Glucocerebrosidase
Immunology
Inflammation
Knockout mouse
MPTP
Microglia
Psychology