Search Results - Seng‐Lai Tan

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  1. 1
    Emerging and diverse roles of protein kinase C in immune cell signalling

    Emerging and diverse roles of protein kinase C in immune cell signalling by Seng‐Lai Tan, Peter J. Parker

    Published 2003
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  2. 2
    How Hepatitis C Virus Counteracts the Interferon Response: The Jury Is Still out on NS5A

    How Hepatitis C Virus Counteracts the Interferon Response: The Jury Is Still out on NS5A by Seng-Lai Tan, Michael G. Katze

    Published 2001
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  3. 3
    Double-Stranded RNA-Independent Dimerization of Interferon-Induced Protein Kinase PKR and Inhibition of Dimerization by the Cellular P58<sup>IPK</sup> Inhibitor

    Double-Stranded RNA-Independent Dimerization of Interferon-Induced Protein Kinase PKR and Inhibition of Dimerization by the Cellular P58<sup>IPK</sup> Inhibitor by Seng-Lai Tan, Michael Gale, Michael G. Katze

    Published 1998
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  4. 4
    Translational Control of Viral Gene Expression in Eukaryotes

    Translational Control of Viral Gene Expression in Eukaryotes by Michael Gale, Seng‐Lai Tan, Michael G. Katze

    Published 2000
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  5. 5
    Hepatitis C therapeutics: current status and emerging strategies

    Hepatitis C therapeutics: current status and emerging strategies by Seng‐Lai Tan, Arnim Pause, Yuguang Shi, Nahum Sonenberg

    Published 2002
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  6. 6
    When Translation Meets Metabolism: Multiple Links to Diabetes

    When Translation Meets Metabolism: Multiple Links to Diabetes by Yuguang Shi, Simeon I. Taylor, Seng-Lai Tan, Nahum Sonenberg

    Published 2003
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  7. 7
    Interaction of the Interferon-Induced PKR Protein Kinase with Inhibitory Proteins P58<sup>IPK</sup> and Vaccinia Virus K3L Is Mediated by Unique Domains: Implications for Kinase Regulation

    Interaction of the Interferon-Induced PKR Protein Kinase with Inhibitory Proteins P58<sup>IPK</sup> and Vaccinia Virus K3L Is Mediated by Unique Domains: Implications for Kinase Re... by Michael Gale, Seng-Lai Tan, Marlene Wambach, Michael G. Katze

    Published 1996
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  8. 8
    Phosphorylation of hepatitis C virus NS5A nonstructural protein: A new paradigm for phosphorylation-dependent viral RNA replication?

    Phosphorylation of hepatitis C virus NS5A nonstructural protein: A new paradigm for phosphorylation-dependent viral RNA replication? by Ying Huang, Kirk A. Staschke, Raffaele De Francesco, Seng‐Lai Tan

    Published 2007
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  9. 9
    Systems biology and the host response to viral infection

    Systems biology and the host response to viral infection by Seng-Lai Tan, Gopinath Ganji, Bryan Paeper, Sean Proll, Michael G. Katze

    Published 2007
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  10. 10
    The Cellular Inhibitor of the PKR Protein Kinase, P58IPK, Is an Influenza Virus-activated Co-chaperone That Modulates Heat Shock Protein 70 Activity

    The Cellular Inhibitor of the PKR Protein Kinase, P58IPK, Is an Influenza Virus-activated Co-chaperone That Modulates Heat Shock Protein 70 Activity by Mark Melville, Seng-Lai Tan, Marlene Wambach, Jaewhan Song, Richard I. Morimoto, Michael G. Katze

    Published 1999
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  11. 11
    Inhibition of Double-Stranded RNA-Dependent Protein Kinase PKR by Vaccinia Virus E3: Role of Complex Formation and the E3 N-Terminal Domain

    Inhibition of Double-Stranded RNA-Dependent Protein Kinase PKR by Vaccinia Virus E3: Role of Complex Formation and the E3 N-Terminal Domain by Patrick R. Romano, Fan Zhang, Seng-Lai Tan, Minerva T. Garcia-Barrio, Michael G. Katze, Thomas Dever, Alan G. Hinnebusch

    Published 1998
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  12. 12
    Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

    Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase by Yupeng He, Haruhisa Nakao, Seng-Lai Tan, Stephen J. Polyak, Petra Neddermann, Sangeetha Vijaysri, Bertram L. Jacobs, Michael G. Katze

    Published 2002
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  13. 13
    NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling

    NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mit... by Seng‐Lai Tan, Haruhisa Nakao, Yupeng He, Sangeetha Vijaysri, Petra Neddermann, Bertram L. Jacobs, Bruce J. Mayer, Michael G. Katze

    Published 1999
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  14. 14
    Evidence That Hepatitis C Virus Resistance to Interferon Is Mediated through Repression of the PKR Protein Kinase by the Nonstructural 5A Protein

    Evidence That Hepatitis C Virus Resistance to Interferon Is Mediated through Repression of the PKR Protein Kinase by the Nonstructural 5A Protein by Michael Gale, Marcus J. Korth, Norina Tang, Seng-Lai Tan, Deborah Hopkins, Thomas Dever, Stephen J. Polyak, David R. Gretch, Michael G. Katze

    Published 1997
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  15. 15
    Resistance to Experimental Autoimmune Encephalomyelitis and Impaired IL-17 Production in Protein Kinase Cθ-Deficient Mice

    Resistance to Experimental Autoimmune Encephalomyelitis and Impaired IL-17 Production in Protein Kinase Cθ-Deficient Mice by Seng‐Lai Tan, Jingyong Zhao, Bi Chen, Xinyi Cynthia Chen, Deena L. Hepburn, Jian Wang, Jonathon D. Sedgwick, Subba R. Chintalacharuvu, Songqing Na

    Published 2006
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  16. 16
    Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation

    Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation by Michael Gale, Collin M. Blakely, Bart Kwieciszewski, Seng-Lai Tan, Michelle L. Dossett, Norina Tang, Marcus J. Korth, Stephen J. Polyak, David R. Gretch, Michael G. Katze

    Published 1998
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  17. 17
    TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation

    TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation by Yi-Hung Ou, Michael J. Torres, Rosalyn Ram, Étienne Formstecher, Christina L. Roland, Tzuling Cheng, Rolf A. Brekken, Ryan P. Wurz, Andrew S. Tasker, Tony Polverino, Seng-Lai Tan, Michael A. White

    Published 2011
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  18. 18
    Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation

    Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation by S Kamel, Linda W. Horton, Loïc Ysebaert, M Levade, Kate Burbury, Seng‐Lai Tan, M. Cole‐Sinclair, John Reynolds, Robin Filshie, S. Schischka, Amit Khot, Shahneen Sandhu, Michael J. Keating, Harshal Nandurkar, Constantine S. Tam

    Published 2014
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  19. 19
    Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties

    Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties by Sonia Schuepbach‐Mallepell, Dolon Das, Laure Willen, Michele Vigolo, Aubry Tardivel, Luc Lebon, Christine Kowalczyk‐Quintas, Josquin Nys, Cristian R. Smulski, Timothy S. Zheng, K. Maskos, Alfred Lammens, Xuliang Jiang, Henry Hess, Seng‐Lai Tan, Pascal Schneider

    Published 2015
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  20. 20
    Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy

    Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: im... by Cheng Liao, Jonathan Hsu, Yong Kim, Dong‐Qing Hu, Daigen Xu, Jun Zhang, Achal Pashine, John G. Menke, Toni Whittard, Natasha Romero, Theresa Truitt, Michelle Slade, Christine Lukacs, Johannes C. Hermann, Mingyan Zhou, Matthew C. Lucas, Satwant K. Narula, Julie A. DeMartino, Seng‐Lai Tan

    Published 2013
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