نتائج البحث - Segrè, Ayellet V

High-Resolution Mutation Mapping Reveals Parallel Experimental Evolution in Yeast حسب Segrè, Ayellet V, Murray, Andrew W, Leu, Jun-Yi

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Pathways Targeted by Antidiabetes Drugs Are Enriched for Multiple Genes Associated With Type 2 Diabetes Risk حسب Segrè, Ayellet V., Wei, Nancy, Altshuler, David, Florez, Jose C.

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Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits حسب Segrè, Ayellet V., Groop, Leif, Mootha, Vamsi K., Daly, Mark J., Altshuler, David

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ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis حسب Kang, Eun Yong, Park, Yurang, Li, Xiao, Segrè, Ayellet V., Han, Buhm, Eskin, Eleazar

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Interaction of background genetic risk, psychotropic medications, and primary angle closure glaucoma in the UK Biobank حسب Sekimitsu, Sayuri, Wang, Jiali, Elze, Tobias, Segrè, Ayellet V., Wiggs, Janey L., Zebardast, Nazlee

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Characteristics of Gln368Ter Myocilin variant and influence of polygenic risk on glaucoma penetrance in the UK Biobank حسب Zebardast, Nazlee, Sekimitsu, Sayuri, Wang, Jiali, Elze, Tobias, Gharahkhani, Puya, Cole, Brian S., Lin, Michael M., Segrè, Ayellet V., Wiggs, Janey L.

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Heterothallism in Saccharomyces cerevisiae isolates from nature: effect of HO locus on the mode of reproduction حسب EZOV, TAL KATZ, CHANG, SHANG-LIN, FRENKEL, ZE’EV, SEGRÈ, AYELLET V., BAHALUL, MORAN, MURRAY, ANDREW W., LEU, JUN-YI, KOROL, ABRAHAM, KASHI, YECHEZKEL

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Colocalization of GWAS and eQTL Signals Detects Target Genes حسب Hormozdiari, Farhad, van de Bunt, Martijn, Segrè, Ayellet V., Li, Xiao, Joo, Jong Wha J., Bilow, Michael, Sul, Jae Hoon, Sankararaman, Sriram, Pasaniuc, Bogdan, Eskin, Eleazar

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Widespread Allelic Heterogeneity in Complex Traits حسب Hormozdiari, Farhad, Zhu, Anthony, Kichaev, Gleb, Ju, Chelsea J.-T., Segrè, Ayellet V., Joo, Jong Wha J., Won, Hyejung, Sankararaman, Sriram, Pasaniuc, Bogdan, Shifman, Sagiv, Eskin, Eleazar

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Photoreceptor layer thinning is an early biomarker for age-related macular degeneration: Epidemiological and genetic evidence from UK Biobank optical coherence tomography data حسب Zekavat, Seyedeh Maryam, Sekimitsu, Sayuri, Ye, Yixuan, Raghu, Vineet, Zhao, Hongyu, Elze, Tobias, Segrè, Ayellet V., Wiggs, Janey L., Natarajan, Pradeep, Del Priore, Lucian, Zebardast, Nazlee, Wang, Jay C.

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The Lin28/let-7 axis regulates glucose metabolism حسب Zhu, Hao, Shyh-Chang, Ng, Segrè, Ayellet V., Shinoda, Gen, Shah, Samar P., Einhorn, William S., Takeuchi, Ayumu, Engreitz, Jesse M., Hagan, John P., Kharas, Michael G, Urbach, Achia, Thornton, James E., Triboulet, Robinson, Gregory, Richard I., Altshuler, David, Daley, George Q.

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Identification of Novel Type 2 Diabetes Candidate Genes Involved in the Crosstalk between the Mitochondrial and the Insulin Signaling Systems حسب Mercader, Josep M., Puiggros, Montserrat, Segrè, Ayellet V., Planet, Evarist, Sorianello, Eleonora, Sebastian, David, Rodriguez-Cuenca, Sergio, Ribas, Vicent, Bonàs-Guarch, Sílvia, Draghici, Sorin, Yang, Chenjing, Mora, Sílvia, Vidal-Puig, Antoni, Dupuis, Josée, Florez, Jose C., Zorzano, Antonio, Torrents, David

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Genetic Analysis in UK Biobank Links Insulin Resistance and Transendothelial Migration Pathways to Coronary Artery Disease حسب Klarin, Derek, Zhu, Qiuyu Martin, Emdin, Connor A., Chaffin, Mark, Horner, Steven, McMillan, Brian J., Leed, Alison, Weale, Michael E., Spencer, Chris C. A., Aguet, François, Segrè, Ayellet V., Ardlie, Kristin G., Khera, Amit V., Kaushik, Virendar K., Natarajan, Pradeep, Consortium, CARDIoGRAMplusC4D, Kathiresan, Sekar

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Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation حسب Gamazon, Eric R., Segrè, Ayellet V., van de Bunt, Martijn, Wen, Xiaoquan, Xi, Hualin S., Hormozdiari, Farhad, Ongen, Halit, Konkashbaev, Anuar, Derks, Eske M., Aguet, François, Quan, Jie, Nicolae, Dan L., Eskin, Eleazar, Kellis, Manolis, Getz, Gad, McCarthy, Mark I., Dermitzakis, Emmanouil T., Cox, Nancy J., Ardlie, Kristin G.

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The human transcriptome across tissues and individuals حسب Melé, Marta, Ferreira, Pedro G., Reverter, Ferran, DeLuca, David S., Monlong, Jean, Sammeth, Michael, Young, Taylor R., Goldmann, Jakob M, Pervouchine, Dmitri D., Sullivan, Timothy J., Johnson, Rory, Segrè, Ayellet V., Djebali, Sarah, Niarchou, Anastasia, Wright, Fred A., Lappalainen, Tuuli, Calvo, Miquel, Getz, Gad, Dermitzakis, Emmanouil T., Ardlie, Kristin G., Guigó, Roderic

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Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development حسب Lage, Kasper, Greenway, Steven C., Rosenfeld, Jill A., Wakimoto, Hiroko, Gorham, Joshua M., Segrè, Ayellet V., Roberts, Amy E., Smoot, Leslie B., Pu, William T., C. Pereira, Alexandre, Mesquita, Sonia M., Tommerup, Niels, Brunak, Søren, Ballif, Blake C., Shaffer, Lisa G., Donahoe, Patricia K., Daly, Mark J., Seidman, Jonathan G., Seidman, Christine E., Larsen, Lars A.

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Deep Learning of the Retina Enables Phenome- and Genome-Wide Analyses of the Microvasculature حسب Zekavat, Seyedeh Maryam, Raghu, Vineet K., Trinder, Mark, Ye, Yixuan, Koyama, Satoshi, Honigberg, Michael C., Yu, Zhi, Pampana, Akhil, Urbut, Sarah, Haidermota, Sara, O’Regan, Declan P., Zhao, Hongyu, Ellinor, Patrick T., Segrè, Ayellet V., Elze, Tobias, Wiggs, Janey L., Martone, James, Adelman, Ron A., Zebardast, Nazlee, Del Priore, Lucian, Wang, Jay C., Natarajan, Pradeep

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Systems Genetics Analysis of GWAS reveals Novel Associations between Key Biological Processes and Coronary Artery Disease حسب Ghosh, Sujoy, Vivar, Juan, Nelson, Christopher P, Willenborg, Christina, Segrè, Ayellet V, Mäkinen, Ville-Petteri, Nikpay, Majid, Erdmann, Jeannette, Blankenberg, Stefan, O'Donnell, Christopher, März, Winfried, Laaksonen, Reijo, Stewart, Alexandre FR, Epstein, Stephen E, Shah, Svati H, Granger, Christopher B, Hazen, Stanley L, Kathiresan, Sekar, Reilly, Muredach P, Yang, Xia, Quertermous, Thomas, Samani, Nilesh J, Schunkert, Heribert, Assimes, Themistocles L, McPherson, Ruth

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Exploiting the GTEx resources to decipher the mechanisms at GWAS loci حسب Barbeira, Alvaro N., Bonazzola, Rodrigo, Gamazon, Eric R., Liang, Yanyu, Park, YoSon, Kim-Hellmuth, Sarah, Wang, Gao, Jiang, Zhuoxun, Zhou, Dan, Hormozdiari, Farhad, Liu, Boxiang, Rao, Abhiram, Hamel, Andrew R., Pividori, Milton D., Aguet, François, Bastarache, Lisa, Jordan, Daniel M., Verbanck, Marie, Do, Ron, Stephens, Matthew, Ardlie, Kristin, McCarthy, Mark, Montgomery, Stephen B., Segrè, Ayellet V., Brown, Christopher D., Lappalainen, Tuuli, Wen, Xiaoquan, Im, Hae Kyung

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Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease حسب Mäkinen, Ville-Petteri, Civelek, Mete, Meng, Qingying, Zhang, Bin, Zhu, Jun, Levian, Candace, Huan, Tianxiao, Segrè, Ayellet V., Ghosh, Sujoy, Vivar, Juan, Nikpay, Majid, Stewart, Alexandre F. R., Nelson, Christopher P., Willenborg, Christina, Erdmann, Jeanette, Blakenberg, Stefan, O'Donnell, Christopher J., März, Winfried, Laaksonen, Reijo, Epstein, Stephen E., Kathiresan, Sekar, Shah, Svati H., Hazen, Stanley L., Reilly, Muredach P., Lusis, Aldons J., Samani, Nilesh J., Schunkert, Heribert, Quertermous, Thomas, McPherson, Ruth, Yang, Xia, Assimes, Themistocles L.

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