Результаты поиска - Segovia, Jose Carlos

Gene Editing for Inherited Red Blood Cell Diseases по Quintana-Bustamante, Oscar, Fañanas-Baquero, Sara, Dessy-Rodriguez, Mercedes, Ojeda-Pérez, Isabel, Segovia, Jose-Carlos

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Altered Hematopoiesis in Mice Lacking DNA Polymerase μ Is Due to Inefficient Double-Strand Break Repair по Lucas, Daniel, Escudero, Beatriz, Ligos, José Manuel, Segovia, Jose Carlos, Estrada, Juan Camilo, Terrados, Gloria, Blanco, Luis, Samper, Enrique, Bernad, Antonio

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Development and Characterization of a Factor V-Deficient CRISPR Cell Model for the Correction of Mutations по Serrano, Luis Javier, Garcia-Arranz, Mariano, De Pablo-Moreno, Juan A., Segovia, José Carlos, Olivera-Salazar, Rocío, Garcia-Olmo, Damián, Liras, Antonio

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The downregulated membrane expression of CD18 in CD34(+) cells defines a primitive population of human hematopoietic stem cells по Mesa-Núñez, Cristina, Leon-Rico, Diego, Aldea, Montserrat, Damián, Carlos, Sanchez-Baltasar, Raquel, Sanchez, Rebeca, Alberquilla, Omaira, Segovia, José Carlos, Bueren, Juan Antonio, Almarza, Elena

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Highly Efficient Genome Editing of Human Hematopoietic Stem Cells via a Nano-Silicon-Blade Delivery Approach по Ma, Yuan, Han, Xin, Bustamante, Oscar Quintana, de Castro, Ricardo Bessa, Zhang, Kai, Zhang, Pengchao, Li, Ying, Liu, Zongbin, Liu, Xuewu, Ferrari, Mauro, Hu, Zhongbo, Segovia, José Carlos, Qin, Lidong

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Efficient and Fast Generation of Relevant Disease Mouse Models by In Vitro and In Vivo Gene Editing of Zygotes по Sanchez-Baltasar, Raquel, Garcia-Torralba, Aida, Nieto-Romero, Virginia, Page, Angustias, Molinos-Vicente, Andrea, López-Manzaneda, Sergio, Ojeda-Pérez, Isabel, Ramirez, Angel, Navarro, Manuel, Segovia, José Carlos, García-Bravo, María

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Who should be eligible for gene therapy clinical trials in red blood cell pyruvate kinase deficiency (PKD)?: Toward an expanded definition of severe PKD по Schwartz, Jonathan D., Barcellini, Wilma, Grace, Rachel F., Bianchi, Paola, Zanella, Alberto, López Lorenzo, José Luis, Sevilla, Julián, Shah, Ami J., Glader, Bertil, Nicoletti, Eileen, Navarro Ordoñez, Susana, Segovia, José Carlos

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Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation по Comella-Bolla, Andrea, Orlandi, Javier G., Miguez, Andrés, Straccia, Marco, García-Bravo, María, Bombau, Georgina, Galofré, Mireia, Sanders, Phil, Carrere, Jordi, Segovia, José Carlos, Blasi, Joan, Allen, Nicholas D., Alberch, Jordi, Soriano, Jordi, Canals, Josep M.

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In Vitro and In Vivo Genetic Disease Modeling via NHEJ-Precise Deletions Using CRISPR-Cas9 по López-Manzaneda, Sergio, Ojeda-Pérez, Isabel, Zabaleta, Nerea, García-Torralba, Aída, Alberquilla, Omaira, Torres, Raúl, Sánchez-Domínguez, Rebeca, Torella, Laura, Olivier, Emmanuel, Mountford, Joanne, Ramírez, Juan C., Bueren, Juan A., González-Aseguinolaza, Gloria, Segovia, Jose-Carlos

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p73 Plays a Role in Erythroid Differentiation through GATA1 Induction по Marqués-García, Fernando, Ferrandiz, Nuria, Fernández-Alonso, Rosalía, González-Cano, Laura, Herreros-Villanueva, Marta, Rosa-Garrido, Manuel, Fernández-García, Belén, Vaque, José P., Marqués, Margarita M., Alonso, María Eugenia, Segovia, José Carlos, León, Javier, Marín, María C.

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Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia по Casado, José A., Valeri, Antonio, Sanchez-Domínguez, Rebeca, Vela, Paula, López, Andrea, Navarro, Susana, Alberquilla, Omaira, Hanenberg, Helmut, Pujol, Roser, Segovia, José-Carlos, Minguillón, Jordi, Surrallés, Jordi, de Heredia, Cristina Díaz, Sevilla, Julián, Rio, Paula, Bueren, Juan A.

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Natural estrogens enhance the engraftment of human hematopoietic stem and progenitor cells in immunodeficient mice по Fañanas-Baquero, Sara, Orman, Israel, Aparicio, Federico Becerra, de Miguel, Silvia Bermudez, Merino, Jordi Garcia, Yañez, Rosa, Sainz, Yolanda Fernandez, Sánchez, Rebeca, Dessy-Rodríguez, Mercedes, Alberquilla, Omaira, Alfaro, David, Zapata, Agustin, Bueren, Juan A., Segovia, Jose Carlos, Quintana-Bustamante, Oscar

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Gene Correction of iPSCs from a Wiskott-Aldrich Syndrome Patient Normalizes the Lymphoid Developmental and Functional Defects по Laskowski, Tamara J., Van Caeneghem, Yasmine, Pourebrahim, Rasoul, Ma, Chao, Ni, Zhenya, Garate, Zita, Crane, Ana M., Li, Xuan Shirley, Liao, Wei, Gonzalez-Garay, Manuel, Segovia, Jose Carlos, Paschon, David E., Rebar, Edward J., Holmes, Michael C., Kaufman, Dan, Vandekerckhove, Bart, Davis, Brian R.

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Worldwide study of hematopoietic allogeneic stem cell transplantation in pyruvate kinase deficiency по van Straaten, Stephanie, Bierings, Marc, Bianchi, Paola, Akiyoshi, Kensuke, Kanno, Hitoshi, Serra, Isabel Badell, Chen, Jing, Huang, Xiaohang, van Beers, Eduard, Ekwattanakit, Supachai, Güngör, Tayfun, Kors, Wijnanda Adriana, Smiers, Frans, Raymakers, Reinier, Yanez, Lucrecia, Sevilla, Julian, van Solinge, Wouter, Segovia, Jose Carlos, van Wijk, Richard

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Enhanced anti-inflammatory effects of mesenchymal stromal cells mediated by the transient ectopic expression of CXCR4 and IL10 по Hervás-Salcedo, Rosario, Fernández-García, María, Hernando-Rodríguez, Miriam, Quintana-Bustamante, Oscar, Segovia, Jose-Carlos, Alvarez-Silva, Marcio, García-Arranz, Mariano, Minguez, Pablo, del Pozo, Victoria, de Alba, Marta Rodríguez, García-Olmo, Damián, Ayuso, Carmen, Lamana, María Luisa, Bueren, Juan A., Yañez, Rosa María

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Generation of NKX2.5(GFP) Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts по López-Muneta, Leyre, Linares, Javier, Casis, Oscar, Martínez-Ibáñez, Laura, González Miqueo, Arantxa, Bezunartea, Jaione, Sanchez de la Nava, Ana Maria, Gallego, Mónica, Fernández-Santos, María Eugenia, Rodriguez-Madoz, Juan Roberto, Aranguren, Xabier L., Fernández-Avilés, Francisco, Segovia, José Carlos, Prósper, Felipe, Carvajal-Vergara, Xonia

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Clinically relevant gene editing in hematopoietic stem cells for the treatment of pyruvate kinase deficiency по Fañanas-Baquero, Sara, Quintana-Bustamante, Oscar, Dever, Daniel P., Alberquilla, Omaira, Sanchez-Dominguez, Rebeca, Camarena, Joab, Ojeda-Perez, Isabel, Dessy-Rodriguez, Mercedes, Turk, Rolf, Schubert, Mollie S., Lattanzi, Annalisa, Xu, Liwen, Lopez-Lorenzo, Jose L., Bianchi, Paola, Bueren, Juan A., Behlke, Mark A., Porteus, Matthew, Segovia, Jose-Carlos

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Midkine signaling maintains the self-renewal and tumorigenic capacity of glioma initiating cells по López-Valero, Israel, Dávila, David, González-Martínez, José, Salvador-Tormo, Nélida, Lorente, Mar, Saiz-Ladera, Cristina, Torres, Sofía, Gabicagogeascoa, Estibaliz, Hernández-Tiedra, Sonia, García-Taboada, Elena, Mendiburu-Eliçabe, Marina, Rodríguez-Fornés, Fátima, Sánchez-Domínguez, Rebeca, Segovia, José Carlos, Sánchez-Gómez, Pilar, Matheu, Ander, Sepúlveda, Juan M., Velasco, Guillermo

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Addressing the diagnostic gaps in pyruvate kinase deficiency: Consensus recommendations on the diagnosis of pyruvate kinase deficiency по Bianchi, Paola, Fermo, Elisa, Glader, Bertil, Kanno, Hitoshi, Agarwal, Archana, Barcellini, Wilma, Eber, Stefan, Hoyer, James D., Kuter, David J., Maia, Tabita Magalhães, del Mar Mañu-Pereira, Maria, Kalfa, Theodosia A., Pissard, Serge, Segovia, José-Carlos, van Beers, Eduard, Gallagher, Patrick G., Rees, David C., van Wijk, Richard

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Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment по Navarro, Susana, Quintana-Bustamante, Oscar, Sanchez-Dominguez, Rebeca, Lopez-Manzaneda, Sergio, Ojeda-Perez, Isabel, Garcia-Torralba, Aida, Alberquilla, Omaira, Law, Kenneth, Beard, Brian C., Bastone, Antonella, Rothe, Michael, Villanueva, Mariela, Ramirez, Juan C., Fañanas-Baquero, Sara, Nieto-Romero, Virginia, Molinos-Vicente, Andrea, Gutierrez, Sonia, Nicoletti, Eileen, García-Bravo, María, Bueren, Juan A., Schwartz, Jonathan D., Segovia, Jose-Carlos

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