Výsledky vyhledávání - Sean O’Keeffe

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  1. 1
    Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape

    Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape Autor Germano Cecere, Sebastian Hoersch, Sean O’Keeffe, Ravi Sachidanandam, Alla Grishok

    Vydáno 2014
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  2. 2
    PASTAA: identifying transcription factors associated with sets of co-regulated genes

    PASTAA: identifying transcription factors associated with sets of co-regulated genes Autor Helge G. Roider, Thomas Manke, Sean O’Keeffe, Martin Vingron, Stefan A. Haas

    Vydáno 2008
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  3. 3
    Sour Sensing from the Tongue to the Brain

    Sour Sensing from the Tongue to the Brain Autor Jin Zhang, Hao Jin, Wenyi Zhang, Cheng Ding, Sean O’Keeffe, Mingyu Ye, Charles S. Zuker

    Vydáno 2019
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  4. 4
    Combinatorial Binding in Human and Mouse Embryonic Stem Cells Identifies Conserved Enhancers Active in Early Embryonic Development

    Combinatorial Binding in Human and Mouse Embryonic Stem Cells Identifies Conserved Enhancers Active in Early Embryonic Development Autor Jonathan Göke, Marc Jung, Sarah Behrens, Lukas Chávez, Sean O’Keeffe, Bernd Timmermann, Hans Lehrach, James Adjaye, Martin Vingron

    Vydáno 2011
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  5. 5
    Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly

    Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly Autor George Mountoufaris, Weisheng V. Chen, Yusuke Hirabayashi, Sean O’Keeffe, Maxime Chevée, Chiamaka L. Nwakeze, Franck Polleux, Tom Maniatis

    Vydáno 2017
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  6. 6
    The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice

    The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice Autor Valeria Gerbino, Esther Kaunga, Junqiang Ye, Daniele Canzio, Sean O’Keeffe, Noam D. Rudnick, Paolo Guarnieri, Cathleen Lutz, Tom Maniatis

    Vydáno 2020
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  7. 7
    The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns

    The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns Autor Jackie Dolan, Karen Walshe, Samantha Alsbury, Karsten Hokamp, Sean O’Keeffe, Tatsuya Okafuji, Suzanne F. C. Miller, Guy Tear, Kevin J. Mitchell

    Vydáno 2007
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  8. 8
    hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function

    hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function Autor Junqiang Ye, Nadine Beetz, Sean O’Keeffe, Juan Carlos Tapia, Lindsey J. Macpherson, Weisheng V. Chen, Rhonda Bassel‐Duby, Eric N. Olson, Tom Maniatis

    Vydáno 2015
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  9. 9
    A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

    A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model Autor Isaac M. Chiu, Emiko Morimoto, Hani Goodarzi, Jennifer T. Liao, Sean O’Keeffe, Hemali Phatnani, Michael A. Muratet, Michael C. Carroll, Shawn Levy, Saeed Tavazoie, R Myers, Tom Maniatis

    Vydáno 2013
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  10. 10
    Pcdhαc2 is required for axonal tiling and assembly of serotonergic circuitries in mice

    Pcdhαc2 is required for axonal tiling and assembly of serotonergic circuitries in mice Autor Weisheng V. Chen, Chiamaka L. Nwakeze, Christine A. Denny, Sean O’Keeffe, Michael A. Rieger, George Mountoufaris, Amy Kirner, Joseph D. Dougherty, René Hen, Qiang Wu, Tom Maniatis

    Vydáno 2017
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  11. 11
    Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells

    Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells Autor Mackenzie W. Amoroso, Gist F. Croft, Damian J. Williams, Sean O’Keeffe, Mónica A. Carrasco, Anne Davis, Laurent Roybon, Derek H. Oakley, Tom Maniatis, Christopher E. Henderson, Hynek Wichterle

    Vydáno 2013
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  12. 12
    Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice

    Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice Autor Daniele Canzio, Chiamaka L. Nwakeze, Adan Horta, Sandy M. Rajkumar, Eliot L. Coffey, Erin E. Duffy, Rachel Duffié, Kevin D. Monahan, Sean O’Keeffe, Matthew D. Simon, Stavros Lomvardas, Tom Maniatis

    Vydáno 2019
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  13. 13
    Intricate interplay between astrocytes and motor neurons in ALS

    Intricate interplay between astrocytes and motor neurons in ALS Autor Hemali Phatnani, Paolo Guarnieri, Brad A. Friedman, Mónica A. Carrasco, Michael A. Muratet, Sean O’Keeffe, Chiamaka L. Nwakeze, Florencia Pauli, Kimberly M. Newberry, Sarah K. Meadows, Juan Carlos Tapia, R Myers, Tom Maniatis

    Vydáno 2013
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  14. 14
    An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

    An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex Autor Ye Zhang, Kenian Chen, Steven A. Sloan, Mariko L. Bennett, Anja R. Scholze, Sean O’Keeffe, Hemali Phatnani, Paolo Guarnieri, Christine Caneda, Nadine Ruderisch, Shuyun Deng, Shane A. Liddelow, Chaolin Zhang, Richard Daneman, Tom Maniatis, Ben A. Barres, Jia Qian Wu

    Vydáno 2014
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  15. 15
    Common and rare variant associations with clonal haematopoiesis phenotypes

    Common and rare variant associations with clonal haematopoiesis phenotypes Autor Michael D. Kessler, Amy Damask, Sean O’Keeffe, Nilanjana Banerjee, Dadong Li, Kyoko Watanabe, Anthony Marketta, Michael Van Meter, Stefan Semrau, Julie Horowitz, Jing Tang, Jack A. Kosmicki, Veera M. Rajagopal, Yuxin Zou, Yariv Houvras, Arkopravo Ghosh, Christopher E. Gillies, Joelle Mbatchou, Ryan R. White, Niek Verweij, Jonas Bovijn, Neelroop Parikshak, Michelle G. LeBlanc, Marcus B. Jones, David J. Glass, Luca A. Lotta, Michael Cantor, Gurinder S. Atwal, Adam E. Locke, Manuel A. R. Ferreira, Raquel P. Deering, Charles Paulding, Alan R. Shuldiner, Gavin Thurston, Adolfo A. Ferrando, Will Salerno, Jeffrey G. Reid, John D. Overton, Jonathan Marchini, Hyun Min Kang, Aris Baras, Gonçalo R. Abecasis, Eric Jorgenson

    Vydáno 2022
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  16. 16
    Exome sequencing and characterization of 49,960 individuals in the UK Biobank

    Exome sequencing and characterization of 49,960 individuals in the UK Biobank Autor Cristopher V. Van Hout, Ioanna Tachmazidou, Joshua Backman, Joshua Hoffman, Daren Liu, Ashutosh Kumar Pandey, Claudia Gonzaga‐Jauregui, Shareef Khalid, Bin Ye, Nilanjana Banerjee, Alexander Li, Colm O’Dushlaine, Anthony Marcketta, Jeffrey Staples, Claudia Schurmann, Alicia Hawes, Evan K. Maxwell, Leland Barnard, Alexander Lopez, John S. Penn, Lukas Habegger, Andrew Blumenfeld, Xiaodong Bai, Sean O’Keeffe, Ashish Yadav, Kavita Praveen, Marcus B. Jones, William Salerno, Wendy K. Chung, Ida Surakka, Cristen J. Willer, Kristian Hveem, Joseph B. Leader, David J. Carey, David H. Ledbetter, Lon R. Cardon, George D. Yancopoulos, Aris N. Economides, Giovanni Coppola, Alan R. Shuldiner, Suganthi Balasubramanian, Michael Cantor, Matthew R. Nelson, John C. Whittaker, Jeffrey G. Reid, Jonathan Marchini, John D. Overton, Robert A. Scott, Gonçalo R. Abecasis, Laura M. Yerges-Armstrong, Aris Baras

    Vydáno 2020
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  17. 17
    Classic Thrombophilias and Thrombotic Risk Among Middle‐Aged and Older Adults: A Population‐Based Cohort Study

    Classic Thrombophilias and Thrombotic Risk Among Middle‐Aged and Older Adults: A Population‐Based Cohort Study Autor Eric Manderstedt, Christina Lind‐Halldén, Christer Halldén, Johan Elf, Peter J. Svensson, Björn Dahlbäck, Gunnar Engström, Olle Melander, Aris Baras, Luca A. Lotta, Bengt Zöller, Gonçalo R. Abecasis, Aris Baras, Michael Cantor, Giovanni Coppola, Aris N. Economides, Luca A. Lotta, John D. Overton, Jeffrey G. Reid, Alan R. Shuldiner, Christina Beechert, Caitlin Forsythe, Erin D. Fuller, Zhenhua Gu, Michael Lattari, Alexander Lopez, John D. Overton, Thomas D. Schleicher, Maria Sotiropoulos Padilla, Louis Widom, Sarah E. Wolf, Manasi Pradhan, Kia Manoochehri, Ricardo H. Ulloa, Xiaodong Bai, Suganthi Balasubramanian, Andrew Blumenfeld, Boris Boutkov, Gisu Eom, Lukas Habegger, Alicia Hawes, Shareef Khalid, Olga Krasheninina, Rouel Lanche, Adam J. Mansfield, Evan K. Maxwell, Mrunali Nafde, Sean O’Keeffe, Max Orelus, Razvan Panea, Tommy Polanco, Ayesha Rasool, Jeffrey G. Reid, William Salerno, Jeffrey Staples, Marcus B. Jones, Jason Mighty, Lyndon J. Mitnaul

    Vydáno 2022
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  18. 18
    Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank

    Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank Autor Sean J. Jurgens, Seung Hoan Choi, Valerie N. Morrill, Mark Chaffin, James P. Pirruccello, Jennifer L. Halford, Lu‐Chen Weng, Victor Nauffal, Carolina Roselli, Amelia Weber Hall, Matthew T. Oetjens, Braxton Lagerman, David P. vanMaanen, Gonçalo R. Abecasis, Xiaodong Bai, Suganthi Balasubramanian, Aris Baras, Christina Beechert, Boris Boutkov, Michael Cantor, Giovanni Coppola, Tanima De, Andrew Deubler, Aris N. Economides, Gisu Eom, Manuel A. R. Ferreira, Caitlin Forsythe, Erin D. Fuller, Zhenhua Gu, Lukas Habegger, Alicia Hawes, Marcus B. Jones, Katia Karalis, Shareef Khalid, Olga Krasheninina, Rouel Lanche, Michael Lattari, Dadong Li, Alexander Lopez, Luca A. Lotta, Kia Manoochehri, Adam J. Mansfield, Evan K. Maxwell, Jason Mighty, Lyndon J. Mitnaul, Mona Nafde, Jonas B. Nielsen, Sean O’Keeffe, Max Orelus, John D. Overton, Maria Sotiropoulos Padilla, Razvan Panea, Tommy Polanco, Manasi Pradhan, Ayesha Rasool, Jeffrey G. Reid, William Salerno, Thomas D. Schleicher, Alan R. Shuldiner, Katherine Siminovitch, Jeffrey Staples, Ricardo H. Ulloa, Niek Verweij, Louis Widom, Sarah E. Wolf, Krishna G. Aragam, Kathryn L. Lunetta, Christopher M. Haggerty, Steven A. Lubitz, Patrick T. Ellinor

    Vydáno 2022
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  19. 19
    Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals

    Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals Autor Jack A. Kosmicki, Julie Horowitz, Nilanjana Banerjee, Rouel Lanche, Anthony Marcketta, Evan K. Maxwell, Xiaodong Bai, Dylan Sun, Joshua Backman, Deepika Sharma, Fabrício S. P. Kury, Hyun Min Kang, Colm O’Dushlaine, Ashish Yadav, Adam J. Mansfield, Alexander Li, Kyoko Watanabe, Lauren Gurski, Shane McCarthy, Adam E. Locke, Shareef Khalid, Sean O’Keeffe, Joelle Mbatchou, Olympe Chazara, Yunfeng Huang, Erika Kvikstad, Amanda O’Neill, Paul Nioi, Meg M. Parker, Slavé Petrovski, Heiko Runz, Joseph D. Szustakowski, Quanli Wang, Emily Wong, Aldo Córdova‐Palomera, Erin N. Smith, Sándor Szalma, Xiuwen Zheng, Sahar Esmaeeli, J. Wade Davis, Yi-Pin Lai, Xing Chen, Anne E. Justice, Joseph B. Leader, Tooraj Mirshahi, David J. Carey, Anurag Verma, Giorgio Sirugo, Marylyn D. Ritchie, Daniel J. Rader, Gundula Povysil, David B. Goldstein, Krzysztof Kiryluk, Erola Pairo‐Castineira, Konrad Rawlik, Dorota Pasko, Susan Walker, Alison Meynert, Athanasios Kousathanas, Loukas Moutsianas, Albert Tenesa, Mark J. Caulfield, Richard H. Scott, James F. Wilson, J. Kenneth Baillie, Guillaume Butler‐Laporte, Tomoko Nakanishi, Mark Lathrop, J. Brent Richards, Marcus B. Jones, Suganthi Balasubramanian, William Salerno, Alan R. Shuldiner, Jonathan Marchini, John D. Overton, Lukas Habegger, Michael Cantor, Jeffrey G. Reid, Aris Baras, Gonçalo R. Abecasis, Manuel A. R. Ferreira

    Vydáno 2021
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  20. 20
    X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes

    X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes Autor Hao Hu, Stefan A. Haas, Jamel Chelly, Hilde Van Esch, Martine Raynaud, Arjan P.M. de Brouwer, Stefanie Weinert, Guy Froyen, Suzanna G.M. Frints, Frédéric Laumonnier, Tomasz Żemojtel, Michael I. Love, Hugues Richard, A-K Emde, Melanie Bienek, Corinna Jensen, M Hambrock, Utz Fischer, Claudia Langnick, Mirjam Feldkamp, W.M. Wissink-Lindhout, Nicolas Lebrun, L. Castelnau, J. Rucci, Rodrick Montjean, Olivier Dorseuil, Pierre Billuart, Till Stuhlmann, M Shaw, Mark Corbett, Alison Gardner, Saffron A.G. Willis‐Owen, Chuan Tan, Kathryn Friend, Stefanie Belet, Kees E. P. van Roozendaal, M Jimenez-Pocquet, M.‐P. Moizard, Nathalie Ronce, Ren Sun, Sean O’Keeffe, R Chenna, Alena van Bömmel, Jonathan Göke, Anna Hackett, Michael Field, Louise Christie, Jackie Boyle, Eric Haan, John W. Nelson, Gillian Turner, Gareth Baynam, Gabriele Gillessen‐Kaesbach, Ulrich Müller, Daniela Steinberger, Bartłomiej Budny, Magdalena Badura‐Stronka, Anna Latos‐Bieleńska, Lilian Bomme Ousager, Peter Wieacker, Germán Rodríguez Criado, M.-L. Bondeson, Göran Annerén, Andreas Dufke, Monika Cohen, Lionel Van Maldergem, C. Vincent‐Delorme, Bernard Échenne, Brigitte Simon‐Bouy, Tjitske Kleefstra, Marjolein H. Willemsen, J-P. Fryns, Koenraad Devriendt, Reinhard Ullmann, Martin Vingron, Klaus Wrogemann, Thomas F. Wienker, Andreas Tzschach, Hans van Bokhoven, Jozef Gécz, Thomas J. Jentsch, W. Chen, H‐H Ropers, Vera M. Kalscheuer

    Vydáno 2015
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