检索结果 - Sean Eckley

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  1. 1
    Conformational-Design-Driven Discovery of EZM0414: A Selective, Potent SETD2 Inhibitor for Clinical Studies

    Conformational-Design-Driven Discovery of EZM0414: A Selective, Potent SETD2 Inhibitor for Clinical Studies 由 Joshua S. Alford, John W. Lampe, Dorothy Brach, Richard Chesworth, Kat Cosmopoulos, Kenneth W. Duncan, Sean Eckley, Jeffrey L. Kutok, Alejandra Raimondi, Thomas V. Riera, Brian C. Shook, Cuyue Tang, Jennifer Totman, Neil A. Farrow

    出版 2022
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  2. 2
    Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery

    Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery 由 Krystyna M. Wozniak, James J. Vornov, Ying Wu, Ying Liu, Valentina Carozzi, Virginia Rodriguez‐Menendez, E Ballarini, Paola Alberti, E Pozzi, Sara Semperboni, Brett M. Cook, Bruce A. Littlefield, K. Nomoto, Krista Condon, Sean Eckley, Christopher DesJardins, Leslie Wilson, Mary Ann Jordan, Stuart C. Feinstein, Guido Cavaletti, Michael Polydefkis, Barbara S. Slusher

    出版 2017
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  3. 3
    Bicyclic azetidines kill the diarrheal pathogen <i>Cryptosporidium</i> in mice by inhibiting parasite phenylalanyl-tRNA synthetase

    Bicyclic azetidines kill the diarrheal pathogen <i>Cryptosporidium</i> in mice by inhibiting parasite phenylalanyl-tRNA synthetase 由 Sumiti Vinayak, Rajiv S. Jumani, Peter G. Miller, Muhammad M. Hasan, Briana I. McLeod, Jayesh Tandel, Erin E. Stebbins, José E. Teixeira, Julien Borrel, Arthur Gonse, Mingliang Zhang, Xianshui Yu, Amy K. Wernimont, Chris Walpole, Sean Eckley, Melissa S. Love, Case W. McNamara, Manmohan Sharma, Amit Sharma, Christina Scherer, Nobutaka Kato, Stuart L. Schreiber, Bruno Melillo, Boris Striepen, Christopher D. Huston, Eamon Comer

    出版 2020
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  4. 4
    H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

    H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers 由 Seiler, Michael, Yoshimi, Akihide, Darman, Rachel, Chan, Betty, Keaney, Gregg, Thomas, Michael, Agrawal, Anant A, Caleb, Benjamin, Csibi, Alfredo, Sean, Eckley, Fekkes, Peter, Karr, Craig, Klimek, Virginia, Lai, George, Lee, Linda, Kumar, Pavan, Chun-Wei Lee, Stanley, Liu, Xiang, Mackenzie, Crystal, Meeske, Carol, Mizui, Yoshiharu, Padron, Eric, Park, Eunice, Pazolli, Ermira, Peng, Shouyong, Prajapati, Sudeep, Taylor, Justin, Teng, Teng, Wang, John, Warmuth, Markus, Yao, Huilan, Yu, Lihua, Zhu, Ping, Abdel-Wahab, Omar, Smith, Peter G, Buonamici, Silvia

    出版 2018
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  5. 5
    Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer

    Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer 由 Xiaoling Puyang, Craig Furman, Guo Zhu Zheng, Zhenhua J. Wu, Deepti Banka, Kiran Aithal, Sergei Agoulnik, David M. Bolduc, Silvia Buonamici, Benjamin Caleb, Subhasree Das, Sean Eckley, Peter Fekkes, Ming‐Hong Hao, Andrew Hart, René Houtman, Sean Irwin, Jaya Julie Joshi, Craig Karr, Amy Kim, Namita Kumar, Pavan Kumar, Galina Kuznetsov, Weidong G. Lai, Nicholas Larsen, Crystal MacKenzie, Lesley‐Ann Martin, Diana Melchers, Alyssa Moriarty, Tuong-Vi Nguyen, John D. Norris, Morgan O’Shea, Sunil Pancholi, Sudeep Prajapati, Sujatha Rajagopalan, Dominic J. Reynolds, Victoria Rimkunas, Nathalie Rioux, Ricardo Ribas, Amy Siu, Sasirekha Sivakumar, Vanitha Subramanian, Michaël Thomas, Frédéric H. Vaillancourt, John Wang, Suzanne E. Wardell, Michael J. Wick, Shihua Yao, Lihua Yu, Markus Warmuth, Peter G. Smith, Ping Zhu, Manav Korpal

    出版 2018
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  6. 6
    Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

    Diversity-oriented synthesis yields novel multistage antimalarial inhibitors 由 Nobutaka Kato, Eamon Comer, Tomoyo Sakata‐Kato, Arvind Sharma, Manmohan Sharma, Micah Maetani, Jessica Bastien, Nicolas M. B. Brancucci, Joshua A. Bittker, Victoria Corey, David C. Clarke, Emily R. Derbyshire, Gillian L. Dornan, Sandra Duffy, Sean Eckley, Maurice A. Itoe, Karin M. J. Koolen, Timothy A. Lewis, Ping S. Lui, Amanda K. Lukens, Emily Lund, Sandra March, Elamaran Meibalan, Bennett C. Meier, Jacob A. McPhail, Branko Mitasev, Eli L. Moss, Morgane Sayes, Yvonne Van Gessel, Mathias J. Wawer, Takashi Yoshinaga, Anne‐Marie Zeeman, Vicky M. Avery, Sangeeta N. Bhatia, John E. Burke, Flaminia Catteruccia, Jon Clardy, Paul A. Clemons, Koen J. Dechering, Jeremy R. Duvall, Michael A. Foley, Fabian Gusovsky, Clemens H. M. Kocken, Matthias Marti, Marshall Morningstar, Benito Muñoz, Daniel E. Neafsey, Amit Sharma, Elizabeth A. Winzeler, Dyann F. Wirth, Christina Scherer, Stuart L. Schreiber

    出版 2016
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