Ngā hua rapu kaituhi

1

An expanding role for cell biologists in drug discovery and pharmacology mā Sorger, Peter K., Schoeberl, Birgit

I whakaputaina 2012

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2

Competing Docking Interactions can Bring About Bistability in the MAPK Cascade mā Legewie, Stefan, Schoeberl, Birgit, Blüthgen, Nils, Herzel, Hanspeter

I whakaputaina 2007

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3

Tensor clustering with algebraic constraints gives interpretable groups of crosstalk mechanisms in breast cancer mā Seigal, Anna, Beguerisse-Díaz, Mariano, Schoeberl, Birgit, Niepel, Mario, Harrington, Heather A.

I whakaputaina 2019

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4

Deciphering the mechanism behind Fibroblast Growth Factor (FGF) induced biphasic signal-response profiles mā Kanodia, Jitendra, Chai, Diana, Vollmer, Jannik, Kim, Jaeyeon, Raue, Andreas, Finn, Greg, Schoeberl, Birgit

I whakaputaina 2014

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5

Autocrine signaling is a key regulatory element during osteoclastogenesis mā Kopesky, Paul, Tiedemann, Kerstin, Alkekhia, Dahlia, Zechner, Christoph, Millard, Bjorn, Schoeberl, Birgit, Komarova, Svetlana V.

I whakaputaina 2014

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6

Effects of Insulin-like Growth Factor-1 and Dexamethasone on Cytokine-Challenged Cartilage: Relevance to Post Traumatic Osteoarthritis mā Li, Yang, Wang, Yang, Chubinskaya, Susanna, Schoeberl, Birgit, Florine, Emily, Kopesky, Paul, Grodzinsky, Alan J.

I whakaputaina 2014

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7

Estimation of immune cell content in tumour tissue using single-cell RNA-seq data mā Schelker, Max, Feau, Sonia, Du, Jinyan, Ranu, Nav, Klipp, Edda, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas

I whakaputaina 2017

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8

Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data mā Chen, William W, Schoeberl, Birgit, Jasper, Paul J, Niepel, Mario, Nielsen, Ulrik B, Lauffenburger, Douglas A, Sorger, Peter K

I whakaputaina 2009

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9

Profiles of Basal and Stimulated Receptor Signaling Networks Predict Drug Response in Breast Cancer Lines mā Niepel, Mario, Hafner, Marc, Pace, Emily A., Chung, Mirra, Chai, Diana H., Zhou, Lili, Schoeberl, Birgit, Sorger, Peter K.

I whakaputaina 2013

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10

HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B mā Kirouac, Daniel C., Du, Jinyan, Lahdenranta, Johanna, Onsum, Matthew D., Nielsen, Ulrik B., Schoeberl, Birgit, McDonagh, Charlotte F.

I whakaputaina 2016

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11

Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making mā Kondic, Anna, Bottino, Dean, Harrold, John, Kearns, Jeffrey D., Musante, CJ, Odinecs, Aleksandrs, Ramanujan, Saroja, Selimkhanov, Jangir, Schoeberl, Birgit

I whakaputaina 2022

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12

Analysis of growth factor signaling in genetically diverse breast cancer lines mā Niepel, Mario, Hafner, Marc, Pace, Emily A, Chung, Mirra, Chai, Diana H, Zhou, Lili, Muhlich, Jeremy L, Schoeberl, Birgit, Sorger, Peter K

I whakaputaina 2014

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13

Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies mā Zhou, Yu, Goenaga, Anne-Laure, Harms, Brian D., Zou, Hao, Lou, Jianlong, Conrad, Fraser, Adams, Gregory P., Schoeberl, Birgit, Nielsen, Ulrik B., Marks, James D.

I whakaputaina 2012

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14

Predicting ligand-dependent tumors from multi-dimensional signaling features mā Hass, Helge, Masson, Kristina, Wohlgemuth, Sibylle, Paragas, Violette, Allen, John E., Sevecka, Mark, Pace, Emily, Timmer, Jens, Stelling, Joerg, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas

I whakaputaina 2017

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15

Rapid optimization and prototyping for therapeutic antibody-like molecules mā Xu, Lihui, Kohli, Neeraj, Rennard, Rachel, Jiao, Yang, Razlog, Maja, Zhang, Kathy, Baum, Jason, Johnson, Bryan, Tang, Jian, Schoeberl, Birgit, Fitzgerald, Jonathan, Nielsen, Ulrik, Lugovskoy, Alexey A.

I whakaputaina 2013

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16

Dual targeting of IGF-1R and ErbB3 as a potential therapeutic regimen for ovarian cancer mā Camblin, Adam J., Tan, Gege, Curley, Michael D., Yannatos, Isabel, Iadevaia, Sergio, Rimkunas, Victoria, Mino-Kenudson, Mari, Bloom, Troy, Schoeberl, Birgit, Drummond, Daryl C., Lugovskoy, Alexey A., Louis, Chrystal U., Askoxylakis, Vasileios

I whakaputaina 2019

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17

Ten simple rules to power drug discovery with data science mā Ferrero, Enrico, Brachat, Sophie, Jenkins, Jeremy L., Marc, Philippe, Skewes-Cox, Peter, Altshuler, Robert C., Gubser Keller, Caroline, Kauffmann, Audrey, Sassaman, Erik K., Laramie, Jason M., Schoeberl, Birgit, Borowsky, Mark L., Stiefl, Nikolaus

I whakaputaina 2020

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18

An ErbB3 antibody, MM-121, is active in cancers with ligand dependent activation mā Schoeberl, Birgit, Faber, Anthony C., Li, Danan, Liang, Mei-Chih, Crosby, Katherine, Onsum, Matthew, Burenkova, Olga, Pace, Emily, Walton, Zandra, Nie, Lin, Fulgham, Aaron, Song, Youngchul, Nielsen, Ulrik B., Engelman, Jeffrey A., Wong, Kwok-Kin

I whakaputaina 2010

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19

An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells mā Sheng, Qing, Liu, Xinggang, Fleming, Eleanor, Yuan, Karen, Piao, Huiying, Chen, Jinyun, Moustafa, Zeinab, Thomas, Roman K., Greulich, Heidi, Schinzel, Anna, Zaghlul, Sara, Batt, David, Ettenberg, Seth, Meyerson, Matthew, Schoeberl, Birgit, Kung, Andrew L., Hahn, William C., Drapkin, Ronny, Livingston, David M., Liu, Joyce F.

I whakaputaina 2010

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20

MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM mā Casaletto, Jessica B., Geddie, Melissa L., Abu-Yousif, Adnan O., Masson, Kristina, Fulgham, Aaron, Boudot, Antoine, Maiwald, Tim, Kearns, Jeffrey D., Kohli, Neeraj, Su, Stephen, Razlog, Maja, Raue, Andreas, Kalra, Ashish, Håkansson, Maria, Logan, Derek T., Welin, Martin, Chattopadhyay, Shrikanta, Harms, Brian D., Nielsen, Ulrik B., Schoeberl, Birgit, Lugovskoy, Alexey A., MacBeath, Gavin

I whakaputaina 2019

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Ngā hua rapu - Schoeberl, Birgit

An expanding role for cell biologists in drug discovery and pharmacology mā Sorger, Peter K., Schoeberl, Birgit

Competing Docking Interactions can Bring About Bistability in the MAPK Cascade mā Legewie, Stefan, Schoeberl, Birgit, Blüthgen, Nils, Herzel, Hanspeter

Tensor clustering with algebraic constraints gives interpretable groups of crosstalk mechanisms in breast cancer mā Seigal, Anna, Beguerisse-Díaz, Mariano, Schoeberl, Birgit, Niepel, Mario, Harrington, Heather A.

Deciphering the mechanism behind Fibroblast Growth Factor (FGF) induced biphasic signal-response profiles mā Kanodia, Jitendra, Chai, Diana, Vollmer, Jannik, Kim, Jaeyeon, Raue, Andreas, Finn, Greg, Schoeberl, Birgit

Autocrine signaling is a key regulatory element during osteoclastogenesis mā Kopesky, Paul, Tiedemann, Kerstin, Alkekhia, Dahlia, Zechner, Christoph, Millard, Bjorn, Schoeberl, Birgit, Komarova, Svetlana V.

Effects of Insulin-like Growth Factor-1 and Dexamethasone on Cytokine-Challenged Cartilage: Relevance to Post Traumatic Osteoarthritis mā Li, Yang, Wang, Yang, Chubinskaya, Susanna, Schoeberl, Birgit, Florine, Emily, Kopesky, Paul, Grodzinsky, Alan J.

Estimation of immune cell content in tumour tissue using single-cell RNA-seq data mā Schelker, Max, Feau, Sonia, Du, Jinyan, Ranu, Nav, Klipp, Edda, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas

Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data mā Chen, William W, Schoeberl, Birgit, Jasper, Paul J, Niepel, Mario, Nielsen, Ulrik B, Lauffenburger, Douglas A, Sorger, Peter K

Profiles of Basal and Stimulated Receptor Signaling Networks Predict Drug Response in Breast Cancer Lines mā Niepel, Mario, Hafner, Marc, Pace, Emily A., Chung, Mirra, Chai, Diana H., Zhou, Lili, Schoeberl, Birgit, Sorger, Peter K.

HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B mā Kirouac, Daniel C., Du, Jinyan, Lahdenranta, Johanna, Onsum, Matthew D., Nielsen, Ulrik B., Schoeberl, Birgit, McDonagh, Charlotte F.

Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making mā Kondic, Anna, Bottino, Dean, Harrold, John, Kearns, Jeffrey D., Musante, CJ, Odinecs, Aleksandrs, Ramanujan, Saroja, Selimkhanov, Jangir, Schoeberl, Birgit

Analysis of growth factor signaling in genetically diverse breast cancer lines mā Niepel, Mario, Hafner, Marc, Pace, Emily A, Chung, Mirra, Chai, Diana H, Zhou, Lili, Muhlich, Jeremy L, Schoeberl, Birgit, Sorger, Peter K

Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies mā Zhou, Yu, Goenaga, Anne-Laure, Harms, Brian D., Zou, Hao, Lou, Jianlong, Conrad, Fraser, Adams, Gregory P., Schoeberl, Birgit, Nielsen, Ulrik B., Marks, James D.

Predicting ligand-dependent tumors from multi-dimensional signaling features mā Hass, Helge, Masson, Kristina, Wohlgemuth, Sibylle, Paragas, Violette, Allen, John E., Sevecka, Mark, Pace, Emily, Timmer, Jens, Stelling, Joerg, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas

Rapid optimization and prototyping for therapeutic antibody-like molecules mā Xu, Lihui, Kohli, Neeraj, Rennard, Rachel, Jiao, Yang, Razlog, Maja, Zhang, Kathy, Baum, Jason, Johnson, Bryan, Tang, Jian, Schoeberl, Birgit, Fitzgerald, Jonathan, Nielsen, Ulrik, Lugovskoy, Alexey A.

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