Search Results - Sbrissa, Diego
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Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P(2) but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane di... by Sbrissa, Diego, Naisan, Ghassan, Ikonomov, Ognian C., Shisheva, Assia
Published 2018Text -
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Sac3 Is an Insulin-regulated Phosphatidylinositol 3,5-Bisphosphate Phosphatase: GAIN IN INSULIN RESPONSIVENESS THROUGH Sac3 DOWN-REGULATION IN ADIPOCYTES by Ikonomov, Ognian C., Sbrissa, Diego, Ijuin, Takeshi, Takenawa, Tadaomi, Shisheva, Assia
Published 2009Text -
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ArPIKfyve Regulates Sac3 Protein Abundance and Turnover: DISRUPTION OF THE MECHANISM BY Sac3(I41T) MUTATION CAUSING CHARCOT-MARIE-TOOTH 4J DISORDER by Ikonomov, Ognian C., Sbrissa, Diego, Fligger, Jason, Delvecchio, Khortnal, Shisheva, Assia
Published 2010Text -
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The PIKfyve-ArPIKfyve-Sac3 triad in human breast cancer: functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines by Ikonomov, Ognian C., Filios, Catherine, Sbrissa, Diego, Chen, Xuequn, Shisheva, Assia
Published 2013Text -
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PIKfyve Controls Fluid Phase Endocytosis but Not Recycling/Degradation of Endocytosed Receptors or Sorting of Procathepsin D by Regulating Multivesicular Body Morphogenesis by Ikonomov, Ognian C., Sbrissa, Diego, Foti, Michelangelo, Carpentier, Jean-Louis, Shisheva, Assia
Published 2003Text -
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Unexpected severe consequences of Pikfyve deletion by aP2‐ or Aq‐promoter‐driven Cre expression for glucose homeostasis and mammary gland development by Ikonomov, Ognian C., Sbrissa, Diego, Delvecchio, Khortnal, A. Rillema, James, Shisheva, Assia
Published 2016Text -
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Active vacuolar H(+) ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P(2) loss under PIKfyve or Vps34 deficiency by Compton, Lauren M., Ikonomov, Ognian C., Sbrissa, Diego, Garg, Puneet, Shisheva, Assia
Published 2016Text -
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Class III PI 3-Kinase is the Main Source of PtdIns3P Substrate and Membrane Recruitment Signal for PIKfyve Constitutive Function in Podocyte Endomembrane Homeostasis by Ikonomov, Ognian C., Sbrissa, Diego, Venkatareddy, Madhusudan, Tisdale, Ellen, Garg, Puneet, Shisheva, Assia
Published 2015Text -
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The Phosphoinositide Kinase PIKfyve Is Vital in Early Embryonic Development: PREIMPLANTATION LETHALITY OF PIKfyve(−/−) EMBRYOS BUT NORMALITY OF PIKfyve(+/−) MICE by Ikonomov, Ognian C., Sbrissa, Diego, Delvecchio, Khortnal, Xie, Yufen, Jin, Jian-Ping, Rappolee, Daniel, Shisheva, Assia
Published 2011Text -
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A Mammalian Ortholog of Saccharomyces cerevisiae Vac14 That Associates with and Up-Regulates PIKfyve Phosphoinositide 5-Kinase Activity by Sbrissa, Diego, Ikonomov, Ognian C., Strakova, Jana, Dondapati, Rajeswari, Mlak, Krzysztof, Deeb, Robert, Silver, Robert, Shisheva, Assia
Published 2004Text -
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Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switching by Ikonomov, Ognian C., Sbrissa, Diego, Delvecchio, Khortnal, Feng, Han-Zhong, Cartee, Gregory D., Jin, Jian-Ping, Shisheva, Assia
Published 2013Text -
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cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease by Fant, Xavier, Durieu, Emilie, Chicanne, Gaëtan, Payrastre, Bernard, Sbrissa, Diego, Shisheva, Assia, Limanton, Emmanuelle, Carreaux, François, Bazureau, Jean-Pierre, Meijer, Laurent
Published 2014Text