Search Results - Saurabh Asthana

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  1. 1
    Transient Sister Chromatid Separation and Elastic Deformation of Chromosomes during Mitosis in Budding Yeast

    Transient Sister Chromatid Separation and Elastic Deformation of Chromosomes during Mitosis in Budding Yeast by Xiangwei He, Saurabh Asthana, Peter K. Sorger

    Published 2000
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  2. 2
    Analysis of Sequence Conservation at Nucleotide Resolution

    Analysis of Sequence Conservation at Nucleotide Resolution by Saurabh Asthana, Mikhail Roytberg, J Stamatoyannopoulos, Shamil Sunyaev

    Published 2007
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  3. 3
    Predicting Protein Complex Membership Using Probabilistic Network Reliability

    Predicting Protein Complex Membership Using Probabilistic Network Reliability by Saurabh Asthana, Oliver D. King, Francis D. Gibbons, Frederick P. Roth

    Published 2004
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  4. 4
    Widely distributed noncoding purifying selection in the human genome

    Widely distributed noncoding purifying selection in the human genome by Saurabh Asthana, William Stafford Noble, Gregory V. Kryukov, Charles E. Grant, Shamil Sunyaev, J Stamatoyannopoulos

    Published 2007
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  5. 5
    Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

    Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity by Matthew T. Chang, Saurabh Asthana, Sizhi Paul Gao, Byron Lee, Jocelyn Chapman, Cyriac Kandoth, Jianjiong Gao, Nicholas D. Socci, David B. Solit, Adam B. Olshen, Nikolaus Schultz, Barry S. Taylor

    Published 2015
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  6. 6
    Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer

    Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer by Luping Lin, Saurabh Asthana, Elton Chan, Sourav Bandyopadhyay, Maria M. Martins, Victor Olivas, Jenny Yan, Luu Pham, Mingxue Michelle Wang, Gideon Bollag, David B. Solit, Eric A. Collisson, Charles M. Rudin, Barry S. Taylor, Trever G. Bivona

    Published 2014
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  7. 7
    Heterogeneous resistance to quizartinib in acute myeloid leukemia revealed by single-cell analysis

    Heterogeneous resistance to quizartinib in acute myeloid leukemia revealed by single-cell analysis by Catherine C. Smith, Amy L. Paguirigan, Grace R. Jeschke, Kimberly C. Lin, Evan Massi, Theodore C. Tarver, Chen-Shan Chin, Saurabh Asthana, Adam B. Olshen, Kevin Travers, Susana Wang, Mark J. Levis, Alexander E. Perl, Jerald P. Radich, Neil P. Shah

    Published 2017
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  8. 8
    NF-κB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer

    NF-κB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer by Collin M. Blakely, Evangelos Pazarentzos, Victor Olivas, Saurabh Asthana, Jenny Yan, Irena Tan, Gorjan Hrustanovic, Elton Chan, Luping Lin, Dana S. Neel, W. H. Newton, Kathryn Bobb, Timothy Fouts, Jeffrey Meshulam, Matthew A. Gubens, David M. Jablons, Jeffrey R. Johnson, Sourav Bandyopadhyay, Nevan J. Krogan, Trever G. Bivona

    Published 2015
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  9. 9
    Inactivation of Capicua drives cancer metastasis

    Inactivation of Capicua drives cancer metastasis by Ross A. Okimoto, Frank Breitenbuecher, Victor Olivas, Wei Wu, Beatrice Gini, Matan Hofree, Saurabh Asthana, Gorjan Hrustanovic, Jennifer C. Flanagan, Asmin Tulpule, Collin M. Blakely, Henry J. Haringsma, Andrew D. Simmons, Kyle Gowen, James Suh, Vincent A. Miller, Siraj M. Ali, Martin Schüler, Trever G. Bivona

    Published 2016
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  10. 10
    Translation control of the immune checkpoint in cancer and its therapeutic targeting

    Translation control of the immune checkpoint in cancer and its therapeutic targeting by Yichen Xu, Mauro Poggio, Hyun Yong Jin, Zhen Shi, Craig M. Forester, Ying Wang, Craig R. Stumpf, Lingru Xue, Emily Devericks, Lomon So, Hao G. Nguyen, Alice Griselin, John D. Gordan, Sarah E. Umetsu, Siegfried Reich, Stephen T. Worland, Saurabh Asthana, Maria Barna, Kevin R. Webster, John T. Cunningham, Davide Ruggero

    Published 2019
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  11. 11
    KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer

    KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer by Michael R. Burgess, Eugene Hwang, Rana Mroue, Craig M. Bielski, Anica M. Wandler, Benjamin J. Huang, Ari Firestone, Amy Young, Jennifer A. Lacap, Lisa Crocker, Saurabh Asthana, Elizabeth M. Davis, Jin Xu, Keiko Akagi, Michelle M. Le Beau, Qing Li, Benjamin Haley, David Stokoe, Deepak Sampath, Barry S. Taylor, Marie Evangelista, Kevin Shannon

    Published 2017
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  12. 12
    A natural killer–dendritic cell axis defines checkpoint therapy–responsive tumor microenvironments

    A natural killer–dendritic cell axis defines checkpoint therapy–responsive tumor microenvironments by Kevin C. Barry, Joy Hsu, Miranda L. Broz, Francisco J. Cueto, Mikhail Binnewies, Alexis J. Combes, Amanda E. Nelson, Kimberly Loo, Raj Kumar, Michael D. Rosenblum, Michael Alvarado, Denise M. Wolf, Dusan Bogunovic, Nina Bhardwaj, Adil Daud, Patrick K. Ha, William R. Ryan, Joshua L. Pollack, Bushra Samad, Saurabh Asthana, Vincent Chan, Matthew F. Krummel

    Published 2018
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  13. 13
    Synthetic Lethality in ATM-Deficient <i>RAD50</i>-Mutant Tumors Underlies Outlier Response to Cancer Therapy

    Synthetic Lethality in ATM-Deficient <i>RAD50</i>-Mutant Tumors Underlies Outlier Response to Cancer Therapy by Hikmat Al‐Ahmadie, Gopa Iyer, Marcel Hohl, Saurabh Asthana, Akiko Inagaki, Nikolaus Schultz, Aphrothiti J. Hanrahan, Sasinya N. Scott, A. Rose Brannon, Gregory McDermott, Mono Pirun, Irina Ostrovnaya, Philip Kim, Nicholas D. Socci, Agnès Viale, Gary K. Schwartz, Victor E. Reuter, Bernard H. Bochner, Jonathan E. Rosenberg, Dean F. Bajorin, Michael F. Berger, John H.J. Petrini, David B. Solit, Barry S. Taylor

    Published 2014
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  14. 14
    Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia

    Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia by Christine M. McMahon, Timothy T. Ferng, Jonathan Canaani, Eunice S. Wang, Jennifer J.D. Morrissette, Dennis J. Eastburn, Maurizio Pellegrino, Robert Durruthy-Durruthy, Christopher D. Watt, Saurabh Asthana, Elisabeth A. Lasater, RosaAnna DeFilippis, Cheryl A.C. Peretz, Lisa H.F. McGary, Safoora Deihimi, Aaron C. Logan, Selina M. Luger, Neil P. Shah, Martin Carroll, Catherine C. Smith, Alexander E. Perl

    Published 2019
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  15. 15
    RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK–positive lung cancer

    RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK–positive lung cancer by Gorjan Hrustanovic, Victor Olivas, Evangelos Pazarentzos, Asmin Tulpule, Saurabh Asthana, Collin M. Blakely, Ross A. Okimoto, Luping Lin, Dana S. Neel, Amit J. Sabnis, Jennifer C. Flanagan, Elton Chan, Marileila Varella‐Garcia, Dara L. Aisner, Aria Vaishnavi, Sai‐Hong Ignatius Ou, Eric A. Collisson, Eiki Ichihara, Philip C. Mack, Christine M. Lovly, Niki Karachaliou, Rafael Rosell, Jonathan W. Riess, Robert C. Doebele, Trever G. Bivona

    Published 2015
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  16. 16
    The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

    The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies by Luping Lin, Amit J. Sabnis, Elton Chan, Victor Olivas, Lindsay Cade, Evangelos Pazarentzos, Saurabh Asthana, Dana S. Neel, Jenny Yan, Xinyuan Lu, Luu Pham, Mingxue M Wang, Niki Karachaliou, María González Cao, José Luís Manzano, José Luis Ramírez, J.M. Sanchez Torres, Fiamma Buttitta, Charles M. Rudin, Eric A. Collisson, Alain P. Algazi, Eric M. Robinson, Iman Osman, Eva Muñoz‐Couselo, Javier Cortés, Dennie T. Frederick, Zachary A. Cooper, Martin McMahon, Antonio Marchetti, Rafael Rosell, Keith T. Flaherty, Jennifer A. Wargo, Trever G. Bivona

    Published 2015
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  17. 17
    Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma

    Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma by Brett Johnson, Tali Mazor, Chibo Hong, Michael J. Barnes, Koki Aihara, Cory Y. McLean, Shaun D. Fouse, Shogo Yamamoto, Hiroki Ueda, Kenji Tatsuno, Saurabh Asthana, Llewellyn E. Jalbert, Sarah J. Nelson, Andrew W. Bollen, W. Clay Gustafson, Elise Charron, William A. Weiss, Ivan Smirnov, Jun S. Song, Adam B. Olshen, Soonmee Cha, Yongjun Zhao, Richard A. Moore, Andrew J. Mungall, Steven J.M. Jones, Martin Hirst, Marco A. Marra, Nobuhito Saito, Hiroyuki Aburatani, Akitake Mukasa, Mitchel S. Berger, Susan M. Chang, Barry S. Taylor, J Costello

    Published 2013
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  18. 18
    Discovering dominant tumor immune archetypes in a pan-cancer census

    Discovering dominant tumor immune archetypes in a pan-cancer census by Alexis J. Combes, Bushra Samad, Jessica Tsui, Nayvin W. Chew, Peter Yan, Gabriella C. Reeder, Divyashree Kushnoor, Alan Shen, Brittany Davidson, Andrea J. Barczak, Michael Adkisson, Austin Edwards, Mohammad Naser, Kevin C. Barry, Tristan Courau, Taymour M. Hammoudi, Rafael J. Argüello, Arjun A. Rao, Adam B. Olshen, Cathy Cai, Jenny Zhan, Katelyn C. Davis, Robin Kate Kelley, Jocelyn Chapman, Chloé E. Atreya, Amar Patel, Adil Daud, Patrick K. Ha, Aarón Díaz, Johannes R. Kratz, Eric A. Collisson, Gabriela K. Fragiadakis, David J. Erle, Alexandre Boissonnas, Saurabh Asthana, Vincent Chan, Matthew F. Krummel, Matthew H. Spitzer, Lawrence Fong, Amanda E. Nelson, Raj Kumar, Justin Lee, Arun Burra, Joy Hsu, Caroline G. Hackett, Karen Tolentino, Jasmine Sjarif, Peter Johnson, Evans Shao, Darrell Abrau, Leonard Lupin, Cole Shaw, Zachary Collins, Tasha Lea, Carlos U. Corvera, Eric K. Nakakura, Julia Carnevale, Michael Alvarado, Kimberley Loo, Lawrence Chen, Melissa Chow, Jennifer R. Grandis, Will G. Ryan, Ivan H. El‐Sayed, David M. Jablons, Gavitt A. Woodard, Maxwell W. Meng, Sima P. Porten, Hideho Okada, Margaret A. Tempero, Andrew H. Ko, Kim Kirkwood, Scott Vandenberg, Denise Guevarra, Erica Oropeza, C. St. Cyr, Pat Glenn, Jennifer Bolen, Amanda Morton, Walter L. Eckalbar

    Published 2021
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  19. 19
    Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19

    Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19 by Lucile Neyton, Ravi K. Patel, Aartik Sarma, K. Mark Ansel, Stephanie A. Christenson, Michael Adkisson, Walter L. Eckalbar, Lenka Maliskova, Andrew Schroeder, Raymund Bueno, M. Grace Gordon, George C. Hartoularos, Divya Kushnoor, David S. Lee, Elizabeth McCarthy, Anton Ogorodnikov, Matthew H. Spitzer, Kamir Hiam, Yun S. Song, Yang Sun, Erden Tumurbaatar, Monique G.P. van der Wijst, Alexander Whatley, Chayse Jones, Saharai Caldera, Catherine DeVoe, Paula Hayakawa Serpa, Christina Love, Eran Mick, Maíra Phelps, Alexandra Tsitsiklis, Carolyn Leroux, Sadeed Rashid, Nicklaus Rodriguez, Kevin Tang, Luz Torres Altamirano, Aleksandra Leligdowicz, Michael A. Matthay, Michael R. Wilson, Chun Ye, Suzanna Chak, Rajani Ghale, Alejandra Jáuregui, Deanna Lee, Nguyễn Hoàng Việt, Austin Sigman, Kirsten N. Kangelaris, Saurabh Asthana, Zachary Collins, Ravi K. Patel, Arjun A. Rao, Bushra Samad, Cole Shaw, Tasha Lea, Alyssa Ward, Norman L. Jones, Jeff Milush, Vincent Chan, Nayvin W. Chew, Alexis J. Combes, Tristan Courau, Kenneth H. Hu, Billy Huang, Nitasha Kumar, Salman Mahboob, Priscila Muñoz-Sandoval, Randy Parada, Gabriella C. Reeder, Alan Shen, Jessica Tsui, Beth Shoshana Zha, Wandi S. Zhu, Andrew Willmore, Sidney C. Haller, Kirsten N. Kangelaris, Walter L. Eckalbar, David J. Erle, Matthew F. Krummel, Carolyn M. Hendrickson, Prescott G. Woodruff, Charles Langelier, Carolyn S. Calfee, Gabriela K. Fragiadakis

    Published 2024
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  20. 20
    Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

    Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project by Ewan Birney, J Stamatoyannopoulos, Anindya Dutta, Roderic Guigó, T Gingeras, Elliott H. Margulies, Zhiping Weng, M Snyder, Emmanouil T. Dermitzakis, Robert E. Thurman, Michael S. Kuehn, Christopher M. Taylor, Shane Neph, Christof Koch, Saurabh Asthana, Ankit Malhotra, Ivan Adzhubei, Jason Greenbaum, Robert Andrews, Paul Flicek, Patrick J. Boyle, Hua Cao, N. P. Carter, Gayle K. Clelland, Sean Davis, Nathan Day, Pawandeep Dhami, Shane C. Dillon, Michael O. Dorschner, Heike Fiegler, Paul G. Giresi, Jeff Goldy, Michael Hawrylycz, Andrew Haydock, Richard Humbert, Keith James, Brett Johnson, Ericka M. Johnson, Tristan Frum, Elizabeth Rosenzweig, Neerja Karnani, Kirsten Lee, Grégory Lefebvre, Patrick A. Navas, Fidencio Neri, Stephen C. J. Parker, Peter J. Sabo, Richard Sandstrom, Anthony Shafer, David Vetrie, Molly Weaver, Sarah Wilcox, Man Yu, Francis S. Collins, Job Dekker, Jason D. Lieb, Thomas D. Tullius, Gregory E. Crawford, Shamil Sunyaev, William Stafford Noble, Ian Dunham, Alexandre Reymond, Philipp Kapranov, Joel Rozowsky, Deyou Zheng, Robert Castelo, Adam Frankish, Jennifer Harrow, Srinka Ghosh, Albin Sandelin, Ivo L. Hofacker, Robert Baertsch, Damian Keefe, Sujit Dike, Jill Cheng, Heather A. Hirsch, Edward A. Sekinger, Julien Lagarde, Josep F. Abril, Atif Shahab, Christoph Flamm, Claudia Fried, Jörg Hackermüller, Jana Hertel, Manja Lindemeyer, Kristin Missal, Andrea Tanzer, Stefan Washietl, Jan O. Korbel, Olof Emanuelsson, Jakob Skou Pedersen, Nancy Holroyd, Ruth Taylor, David Swarbreck, Nicholas Matthews, Mark Dickson, Daryl J. Thomas, Matthew T. Weirauch, James Gilbert, Jörg Drenkow

    Published 2007
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