檢索結果 - Saunthararajah, Yogen

Targets of opportunity for precision medicine 由 Saunthararajah, Yogen

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Targeting sickle cell disease root-cause pathophysiology with small molecules 由 Saunthararajah, Yogen

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Mysteries of partial dihydroorotate dehydrogenase inhibition and leukemia terminal differentiation 由 Saunthararajah, Yogen

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β-Hemoglobinopathies lead the way 由 Saunthararajah, Yogen

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Epigenetic modifier directed therapeutics to unleash healthy genes in unhealthy cells 由 Jha, Babal K., Saunthararajah, Yogen

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5-aza-2′,2′-Difluroro Deoxycytidine (NUC013): A Novel Nucleoside DNA Methyl Transferase Inhibitor and Ribonucleotide Reductase Inhibitor for the Treatment of Cancer 由 Daifuku, Richard, Hu, Zhenbo, Saunthararajah, Yogen

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Severe pyoderma gangrenosum caused by myelodysplastic syndrome successfully treated with decitabine administered by a noncytotoxic regimen 由 Saleh, Mostafa F. M., Saunthararajah, Yogen

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Fetal Hemoglobin Induction by Epigenetic Drugs 由 Lavelle, Donald, Engel, James Douglas, Saunthararajah, Yogen

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Differentiation therapy and the mechanisms that terminate cancer cell proliferation without harming normal cells 由 Enane, Francis O., Saunthararajah, Yogen, Korc, Murray

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High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects 由 Ebrahem, Quteba, Mahfouz, Reda, Ng, Kwok Peng, Saunthararajah, Yogen

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Decitabine Suspends Human CD34(+) Cell Differentiation and Proliferation during Lentiviral Transduction 由 Uchida, Naoya, Hsieh, Matthew M., Platner, Charlotte, Saunthararajah, Yogen, Tisdale, John F.

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Clinical Trials Assessing Hypomethylating Agents Combined with Other Therapies: Causes for Failure and Potential Solutions 由 Zavras, Phaedon D., Shastri, Aditi, Goldfinger, Mendel, Verma, Amit K., Saunthararajah, Yogen

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A non‐cytotoxic regimen of decitabine to treat refractory T‐cell large granular lymphocytic leukemia 由 Zawit, Misam, Gurnari, Carmelo, Pagliuca, Simona, Awada, Hassan, Maciejewski, Jaroslaw P., Saunthararajah, Yogen

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Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo 由 Alcazar, Oscar, Achberger, Susan, Aldrich, Wayne, Hu, Zhenbo, Negrotto, Soledad, Saunthararajah, Yogen, Triozzi, Pierre

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Subchronic oral toxicity study of Decitabine (DAC) in Combination with Tetrahydrouridine (THU) in CD-1 Mice 由 Terse, Pramod, Engelke, Kory, Chan, Kenneth, Ling, Yonghua, Sharpnack, Douglas, Saunthararajah, Yogen, Covey, Joe

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Tracking Decitabine Incorporation into Malignant Myeloid Cell DNA in vitro and in vivo by LC-MS/MS with Enzymatic Digestion 由 Chilakala, Sujatha, Feng, Ye, Li, Lan, Mahfouz, Reda, Quteba, Ebrahem, Saunthararajah, Yogen, Xu, Yan

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Gender Differences in Cytidine Deaminase Expression/Activity Contributes to Decreased Cytidine Analog Half-life and Likely Contributes to Worse Outcomes with 5-azacytidine or Decit... 由 Mahfouz, Reda, Koh, Lip Seng, Teo, Marissa, Chee, Chit Lai, Toh, Han Chong, Saunthararajah, Yogen

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Association of tumor and plasma microRNA expression with tumor monosomy-3 in patients with uveal melanoma 由 Triozzi, Pierre L., Achberger, Susan, Aldrich, Wayne, Crabb, John W., Saunthararajah, Yogen, Singh, Arun D.

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Molecular profiling of primary uveal melanomas with tumor-infiltrating lymphocytes 由 Triozzi, Pierre L, Schoenfield, Lynn, Plesec, Thomas, Saunthararajah, Yogen, Tubbs, Raymond R, Singh, Arun D

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AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model 由 Wunderlich, Mark, Mizukawa, Benjamin, Chou, Fu-Sheng, Sexton, Christina, Shrestha, Mahesh, Saunthararajah, Yogen, Mulloy, James C.

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