检索结果 - Saul Jaime‐Figueroa

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  1. 1
    Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties

    Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties 由 Saul Jaime‐Figueroa, Alexandru D. Buhimschi, Momar Toure, John Hines, Craig M. Crews

    出版 2019
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  2. 2
    Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of Structure–Degradation Relationships

    Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of Structure–Degradation Relationships 由 George M. Burslem, Philipp Ottis, Saul Jaime‐Figueroa, Alicia Morgan, Philipp M. Cromm, Momar Toure, Craig M. Crews

    出版 2018
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  3. 3
    Modular PROTAC Design for the Degradation of Oncogenic BCR‐ABL

    Modular PROTAC Design for the Degradation of Oncogenic BCR‐ABL 由 Ashton C. Lai, Momar Toure, Doris Hellerschmied, Jemilat Salami, Saul Jaime‐Figueroa, Eunhwa Ko, John Hines, Craig M. Crews

    出版 2015
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  4. 4
    Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase

    Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase 由 Blake E. Smith, Stephen L. Wang, Saul Jaime‐Figueroa, Alicia Harbin, Jing Wang, Brian D. Hamman, Craig M. Crews

    出版 2019
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  5. 5
    Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs)

    Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs) 由 Po‐Han Chen, Zhenyi Hu, Elvira An, Ifunanya Okeke, Sijin Zheng, Xuanmeng Luo, Angela Gong, Saul Jaime‐Figueroa, Craig M. Crews

    出版 2021
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  6. 6
    Mutant-selective degradation by BRAF-targeting PROTACs

    Mutant-selective degradation by BRAF-targeting PROTACs 由 Shanique Alabi, Saul Jaime‐Figueroa, Zhan Yao, Yijun Gao, John Hines, Kusal T. G. Samarasinghe, Lea Vogt, Neal Rosen, Craig M. Crews

    出版 2021
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  7. 7
    Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras

    Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras 由 Kusal T. G. Samarasinghe, Saul Jaime‐Figueroa, Michael Burgess, Dhanusha A. Nalawansha, Katherine Dai, Zhenyi Hu, Adrian M. Bebenek, Scott A. Holley, Craig M. Crews

    出版 2021
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  8. 8
    Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead

    Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead 由 Daniel P. Bondeson, Blake E. Smith, George M. Burslem, Alexandru D. Buhimschi, John Hines, Saul Jaime‐Figueroa, Jing Wang, Brian D. Hamman, Alexey Ishchenko, Craig M. Crews

    出版 2017
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  9. 9
    The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

    The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study 由 George M. Burslem, Blake E. Smith, Ashton C. Lai, Saul Jaime‐Figueroa, Daniel McQuaid, Daniel P. Bondeson, Momar Toure, Hanqing Dong, Yimin Qian, Jing Wang, Andrew P. Crew, John Hines, Craig M. Crews

    出版 2017
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